KEGG   Oreochromis aureus (blue tilapia): 116319019
Entry
116319019         CDS       T07295                                 
Symbol
map2k2b
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 2b
  KO
K04369  mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
Organism
oau  Oreochromis aureus (blue tilapia)
Pathway
oau04010  MAPK signaling pathway
oau04012  ErbB signaling pathway
oau04068  FoxO signaling pathway
oau04140  Autophagy - animal
oau04148  Efferocytosis
oau04150  mTOR signaling pathway
oau04210  Apoptosis
oau04218  Cellular senescence
oau04270  Vascular smooth muscle contraction
oau04370  VEGF signaling pathway
oau04371  Apelin signaling pathway
oau04540  Gap junction
oau04620  Toll-like receptor signaling pathway
oau04810  Regulation of actin cytoskeleton
oau04910  Insulin signaling pathway
oau04912  GnRH signaling pathway
oau04916  Melanogenesis
oau05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:oau00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116319019 (map2k2b)
   04012 ErbB signaling pathway
    116319019 (map2k2b)
   04370 VEGF signaling pathway
    116319019 (map2k2b)
   04371 Apelin signaling pathway
    116319019 (map2k2b)
   04068 FoxO signaling pathway
    116319019 (map2k2b)
   04150 mTOR signaling pathway
    116319019 (map2k2b)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    116319019 (map2k2b)
   04148 Efferocytosis
    116319019 (map2k2b)
  09143 Cell growth and death
   04210 Apoptosis
    116319019 (map2k2b)
   04218 Cellular senescence
    116319019 (map2k2b)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    116319019 (map2k2b)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    116319019 (map2k2b)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    116319019 (map2k2b)
  09152 Endocrine system
   04910 Insulin signaling pathway
    116319019 (map2k2b)
   04912 GnRH signaling pathway
    116319019 (map2k2b)
   04916 Melanogenesis
    116319019 (map2k2b)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    116319019 (map2k2b)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    116319019 (map2k2b)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oau01001]
    116319019 (map2k2b)
Enzymes [BR:oau01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     116319019 (map2k2b)
Protein kinases [BR:oau01001]
 Serine/threonine kinases: STE group
  STE7 family
   116319019 (map2k2b)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like Haspin_kinase Seadorna_VP7 APH
Other DBs
NCBI-GeneID: 116319019
NCBI-ProteinID: XP_031594094
Ensembl: ENSOABG00000000729
UniProt: A0A668RCZ6
LinkDB
Position
LG18:complement(13034884..13041992)
AA seq 395 aa
MAPKKRPVPLNIAPASDGLSTSTNTEITSEANLEALKKILEELDLDEQQKKRLEAFLTQK
AKVGELKDDDFHRICELGAGNGGVVNKECHKPSGIIMARKLIHLEIKPAIRNQIIRELQV
LHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVMKEAKRIPEEILGKVSIAVLRGL
AYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQG
THYSVQSDVWSMGLSLVELSVGRFPIPPPDAKELEAIFGRPILDDAQGETHSTSPRPRPP
GRPVSGHGPVMAIFELLDYIVNEPPPKLPHGVFTPDFQDFVTKCLIKNPADRADLKMLMN
HTFIKRSEAEEVDFAGWLCKTMELNQPSTPTRTTD
NT seq 1188 nt   +upstreamnt  +downstreamnt
atggctcctaaaaagagaccagtgcccttaaacattgctcctgctagtgatggattatcc
acctccaccaatacagagattacatctgaggccaatttagaagcgttgaagaaaatactg
gaggagctggacctggatgaacagcaaaagaaaagattagaagctttccttacccagaag
gccaaggttggggagctgaaagatgatgacttccatcgtatctgcgagctgggtgcaggc
aacggaggagtggtcaacaaggagtgccacaaaccttcaggcataatcatggccagaaaa
ctcatacatttagaaataaaacctgcaataagaaaccagatcatcagagagctccaggta
ctacacgagtgtaattctccctacattgtgggcttctatggagctttttacagcgatgga
gaaatcagcatctgcatggaacacatggatggtggctctctggaccaggtgatgaaagaa
gcaaagcggattcctgaagagattctgggcaaagtcagcattgctgttttgagaggcctt
gcctacctaagagaaaaacatcaaatcatgcatagagatgtgaagccctcaaacatcctg
gtaaactcacgcggggagatcaagctgtgtgactttggtgtgagtgggcagctcatagac
tcgatggccaattcctttgttgggacaagatcctacatgtcgcctgagagattgcagggg
actcattactctgtgcagtctgatgtgtggagtatgggcttgtcccttgtagagctgtca
gttggacgctttcccatcccccctccagatgctaaggagctggaggccatatttggacga
ccgatcttggatgatgcacagggagagacccacagcacatcccctagacccagacctccg
ggtagacctgttagtggccacggtccggtaatggctatctttgaactactagactacatt
gtcaatgagccaccacctaaactaccccatggagtattcacccctgattttcaggatttt
gtgaccaagtgtctcatcaaaaatccagcagacagggctgacttaaaaatgttaatgaac
cacacatttatcaagcggtctgaagcagaggaggtggatttcgctgggtggctttgtaaa
acaatggaactgaaccaacccagcactcccacacgcactacagattga

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