KEGG   Ovis canadensis (bighorn sheep): 138434419
Entry
138434419         CDS       T11679                                 
Symbol
PINK1
Name
(RefSeq) serine/threonine-protein kinase PINK1, mitochondrial
  KO
K05688  PTEN induced putative kinase 1 [EC:2.7.11.1]
Organism
ocan  Ovis canadensis (bighorn sheep)
Pathway
ocan04137  Mitophagy - animal
ocan05012  Parkinson disease
ocan05014  Amyotrophic lateral sclerosis
ocan05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:ocan00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    138434419 (PINK1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    138434419 (PINK1)
   05014 Amyotrophic lateral sclerosis
    138434419 (PINK1)
   05022 Pathways of neurodegeneration - multiple diseases
    138434419 (PINK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocan01001]
    138434419 (PINK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ocan04131]
    138434419 (PINK1)
   03029 Mitochondrial biogenesis [BR:ocan03029]
    138434419 (PINK1)
Enzymes [BR:ocan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     138434419 (PINK1)
Protein kinases [BR:ocan01001]
 Serine/threonine kinases: Other
  NKF2 family
   138434419 (PINK1)
Membrane trafficking [BR:ocan04131]
 Autophagy
  Mitophagy
   PINK1-Parkin associated proteins
    138434419 (PINK1)
Mitochondrial biogenesis [BR:ocan03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    138434419 (PINK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like APH
Other DBs
NCBI-GeneID: 138434419
NCBI-ProteinID: XP_069435190
LinkDB
Position
2:complement(251260980..251278205)
AA seq 587 aa
MAVRQALGRGLQLGRALLLRFTAKPGPAYGWGRPERPGPAAGWGRGERPGPAAGPGTEPC
RLGLGLPGRYRFFRQSVAGLAERLQQQFVVRARGGAGPRGRAVFLAFGLGLGLIEEKQAE
GRRAASACEEIQAVFTQKNKLLPDPLDTRRWQGFRLEEYLIGQSIGKGCSAAVYEAAMPV
LPRNLEEAESLGQLLPGKGPEILPRGEEVLAPRAPAFPLAIKMMWNISAGSSSEAIFSAM
SQELVPASRVAVAGEYGAATPGRPKGGPKQLAPHPNIIRVLRAFTSSVPLLPGALVDYPD
VLPPCLHPAGLGHGRTLFLVMKNYPCTLRQYLRGNTPSPRLATVMTLQLLEAVDHLVQQG
VAHRDLKSDNILVELDADGCPWLVITDFGCCLADERVGLQLPFTSWYVDRGGNGCLMAPE
VSTACPGPRAVIDYSKADAWAVGALAYEIFGLPNPFYGQGRAHLESRSYQEAQLPALPEW
VPWDVRCLVRSLLQREACKRPSARVAANVLHLSLWGEHTLALKNLKPDEMIGWLLQQSAA
TLLANRLTENCVETKMKMLFLANLEYEALSQAALLLDSWRAAPRQLL
NT seq 1764 nt   +upstreamnt  +downstreamnt
atggcggtgcgacaagcgctgggccgaggcctgcagctgggccgagcgctgctcctgcgc
ttcacggccaagcccggcccggcctacggctggggccggccggagcggcccggccccgcg
gcgggctggggtcgcggagagcgcccgggcccggccgcgggacccggcacggagccgtgc
aggctcgggctcgggcttcccggccgctaccgcttcttccgccagtcggtggccgggctg
gcggagcggctccagcagcagttcgtggtgcgagcccggggcggtgcgggccctcgcggc
cgcgctgtctttctggccttcgggcttgggctgggcctcatcgaggagaagcaagcggag
ggccggcgggccgcctcagcctgtgaggagattcaggcagttttcacccagaaaaacaag
ctgctcccggacccactggacacccgacgctggcagggtttccggctggaggagtatctg
atcgggcagtccattggcaagggctgcagcgccgccgtctatgaggccgccatgcctgtg
ttgccccggaacctggaggaggcagagagcctgggccagcttcttccagggaagggccca
gagatccttccacggggagaggaggtgctggccccgcgggccccggccttccccttggcc
atcaagatgatgtggaacatctcggcaggctcatccagcgaagccatctttagcgcaatg
agccaggagctggtcccagccagtcgagtggccgtggccggggagtatggagcggccact
cccggaagacccaagggaggtcccaagcagctggccccgcaccccaacatcatccgggtc
ttgcgagccttcacctcgtcggtgccgctgctgccaggagccctggtcgactacccagat
gtgctgcccccctgtcttcaccccgcaggcctgggccacgggcggactctcttccttgtc
atgaagaactacccctgtaccctgcgccagtaccttcgcgggaacaccccgagcccccgg
ctggccactgtgatgactctgcagctcttggaagcagtggatcacctggtccagcagggc
gtcgcgcacagagacctgaagtccgacaacatccttgtggaactggacgcagacggctgc
ccctggttggtgatcacagactttggctgctgcttggctgatgagcgcgtcggcctgcag
ttgcctttcaccagctggtacgtggaccgcggcggaaatggctgcctgatggctcctgag
gtgtccacggcctgccctggccccagggcagtgatcgactacagcaaggcggatgcctgg
gcggtgggcgcactcgcctatgaaatctttgggctccccaatcccttttacggccagggc
agggcccaccttgaaagccgcagttaccaggaggctcagctgccagcactgcccgagtgg
gtgccgtgggacgtgaggtgcctggtgaggtcgctgctgcagcgggaggcttgcaagagg
ccatccgcccgagtggctgctaacgtgcttcacttaagcctctggggtgaacacacgctc
gccctgaagaacctgaaaccagacgagatgattggctggctcctccaacaatcggccgcc
actctgctggccaacagactgacggagaactgtgtggaaacgaaaatgaagatgctgttt
ctggccaacctggagtatgaagcgctgagccaggcggccctcctcctcgactcctggagg
gcggccccgagacagctgctgtag

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