KEGG   Ovis canadensis (bighorn sheep): 138440479
Entry
138440479         CDS       T11679                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ocan  Ovis canadensis (bighorn sheep)
Pathway
ocan00670  One carbon pool by folate
ocan00790  Folate biosynthesis
ocan01100  Metabolic pathways
ocan01240  Biosynthesis of cofactors
ocan01523  Antifolate resistance
ocan04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:ocan00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    138440479 (DHFR)
   00670 One carbon pool by folate
    138440479 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    138440479 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    138440479 (DHFR)
Enzymes [BR:ocan01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     138440479 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 138440479
NCBI-ProteinID: XP_069446153
LinkDB
Position
5:complement(93305186..93320542)
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKNGNLPWPPLRNEFKYFQRMTTVSSEEGKQNLVIMGRKTWFS
IPEKNRPLKDRINIVLSRELKEPPKGAHFLAKSLDDALELIEDPELTNKVDMVWIVGGSS
VYKEAMNKPGHLRLFVTRIMQEFESDVFFPEIDFEKYKLLPEYPGVPLDVQEEKGIKYKF
EVYEKNN
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtccgctaaactgcatcgtcgctgtgtcccagaacatgggcatcggcaagaac
gggaacctgccctggccaccactcaggaatgaattcaagtatttccaaagaatgactaca
gtctcttcagaagaaggtaaacagaatttggtgattatgggtaggaagacctggttctcc
attccagagaagaatcgacctttaaaggacagaattaatatagttctcagtagagaactc
aaggaacctccaaagggagctcattttcttgccaaaagtctggatgatgccttagaactt
attgaagatccagaattaacaaataaagtagacatggtttggatagtgggaggcagttct
gtttataaggaagccatgaacaagccaggccatcttagactatttgtgacaaggatcatg
caagaatttgaaagtgatgtgtttttcccagaaattgattttgaaaaatataaacttctt
ccagaatatccaggtgttcctttggatgtccaggaggaaaaaggcattaagtacaaattt
gaagtatatgaaaagaacaattaa

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