Ovis canadensis (bighorn sheep): 138444875
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Entry
138444875 CDS
T11679
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
ocan Ovis canadensis (bighorn sheep)
Pathway
ocan01524
Platinum drug resistance
ocan04010
MAPK signaling pathway
ocan04071
Sphingolipid signaling pathway
ocan04141
Protein processing in endoplasmic reticulum
ocan04210
Apoptosis
ocan04530
Tight junction
ocan04668
TNF signaling pathway
ocan04714
Thermogenesis
ocan04722
Neurotrophin signaling pathway
ocan04932
Non-alcoholic fatty liver disease
ocan04936
Alcoholic liver disease
ocan05010
Alzheimer disease
ocan05012
Parkinson disease
ocan05014
Amyotrophic lateral sclerosis
ocan05016
Huntington disease
ocan05017
Spinocerebellar ataxia
ocan05022
Pathways of neurodegeneration - multiple diseases
ocan05208
Chemical carcinogenesis - reactive oxygen species
ocan05417
Lipid and atherosclerosis
ocan05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ocan00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
138444875 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
138444875 (MAP3K5)
04668 TNF signaling pathway
138444875 (MAP3K5)
04071 Sphingolipid signaling pathway
138444875 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
138444875 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
138444875 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
138444875 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
138444875 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
138444875 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
138444875 (MAP3K5)
05012 Parkinson disease
138444875 (MAP3K5)
05014 Amyotrophic lateral sclerosis
138444875 (MAP3K5)
05016 Huntington disease
138444875 (MAP3K5)
05017 Spinocerebellar ataxia
138444875 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
138444875 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
138444875 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
138444875 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
138444875 (MAP3K5)
04932 Non-alcoholic fatty liver disease
138444875 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
138444875 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ocan01001
]
138444875 (MAP3K5)
Enzymes [BR:
ocan01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
138444875 (MAP3K5)
Protein kinases [BR:
ocan01001
]
Serine/threonine kinases: STE group
STE11 family
138444875 (MAP3K5)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
138444875
NCBI-ProteinID:
XP_069454571
LinkDB
All DBs
Position
8:complement(72630600..72861762)
Genome browser
AA seq
1366 aa
AA seq
DB search
MSAEAGEGITFSVPPFAEGGSYRRGGAATAAEGEETQLPPPPPGSFWNVESAAAPGAGCP
SATAGSSATRCRGNSGGGGGRRTTVAYVINEASQGQLVVAESEALQCLREACETVGAALE
TLHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTN
SDSLQSLKEIICQKNTMCTGNYTFIPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGP
ICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEV
LTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDR
AKALDIMIPLVQNEEQVASDMYCLVGRIYKDMFLDSNFMDTESRDHGASWFKKAFESEPT
LQSGINYAVLLLASGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLA
NDHLRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTSEQPVAKQELVDFWMDFLVE
ATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASS
VRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGKNTEEGDCEG
DSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIAL
HKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQIL
EGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAP
EIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMS
AEAKAFILKCFEPDPDKRDCANDLLMDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLP
VPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGEKDVKGIRTLFLGIPDENFEDH
SAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEEPKLKWEHIT
TLVTSLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIK
PHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEGDHDERPSNQTVR
RPHAVLEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELVQKEKELQA
LLHQAIEEKDQEIKHLKLKSQPIDIPGLPACHSSSPGTNTEDSELTDWLRENGADEDTIS
RFLAEDYSLMDVLYYVTRDDLKCLRLRGGMLCTLWKAITDFRDKQA
NT seq
4101 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcggaggcgggcgagggcatcactttctccgtgccgcccttcgccgagggcggc
agctaccggaggggaggagcggcgacggcggccgagggcgaggagacccagctgccaccg
ccgccaccgggcagcttctggaacgtggaaagtgccgccgctcccggcgccgggtgtccc
agtgccaccgctgggagcagcgccacccggtgccggggcaactctgggggcggaggcggc
cgacggaccacggtggcctatgtcatcaacgaggcgagccaggggcagctggtggtggcc
gagagcgaggccctgcagtgcctgcgggaggcgtgcgagacggtgggcgccgccctggag
accctgcattttgggaaactggactttggagaaactgcggtgctggaccgattttacaat
gcagatatcgccgtggtggagatgagcgatgccttccgacaaccatccttattttaccac
ctgggagtgcgagaaagtttcagcatggccaacaacatcatcctctactgtgatactaat
tcagactctctgcagtcactgaaggagatcatttgccagaagaatactatgtgcactggg
aactacacatttattccttacatgataacgccgcataacaaggtctactgctgtgacagc
agcttcatgaagggcttgactgagctcatgcagccgaactttgagctgcttctgggaccc
atctgcttacctcttgtggatcgtttcattcagctcttgaaggtggcacaagcaagttcc
agccagtatttccgggagtctatactcaatgatatcaggaaagctcgtaacttatatact
ggcaaagaactggcagctgaattggcaagaattcgacagcgagtggataatattgaagtc
ttgacagcagatattgtcataaatctgttactttcatatagagatatccaggactatgat
tctattgtgaagctggtagagactttagaaaagcttccaacgtttgatttggcctcccat
caccatgtgaagtttcattatgcatttgcactgaataggagaaacctccctggagataga
gcaaaagctcttgacattatgattcccctggtgcaaaatgaagagcaggttgcttcagat
atgtattgccttgttggtagaatctacaaagatatgtttttggactctaatttcatggac
actgaaagtagagaccatggagcctcttggttcaaaaaggcatttgaatcagagccaaca
ctacagtcaggaattaattatgcggtcctcctcctggcatctgggcaccagtttgaatct
tcctttgagctccgaaaagttggggtgaagctaagtagtcttcttggtaaaaagggaaac
ttggaaaaactccagagctactgggaagttggatttttcctgggggccagtgtcctggcc
aatgaccacttgagagtcattcaagcatctgaaaagctttttaaactgaagacacctgca
tggtacctcaagtctatcgtagagacaattttgatatataagcattttgtgaaactgact
tcggaacagcctgtggccaaacaggaacttgtggacttctggatggatttcctggtcgag
gccacaaagacagatgtcactgtagttaggtttccagtattaatattagaaccaaccaaa
atctatcaaccttcgtatttgtctatcaacaatgaagttgaggaaaagacaatatctatt
tggcacgtgcttcctgatgacaagaaaggtatacatgagtggaattttagtgcttcttct
gtcaggggtgtgagtatttctaaatttgaagaacgatgctgttttctgtatgtgcttcac
aattctgacgatttccaaatctatttctgtacagaacttcactgtaaaaagttttttgaa
atggtgaacaccattactgaagagaaggggaaaaacacagaggaaggagattgtgaaggt
gactccctggagtatgactatgaatacgatgaaaatggtgacagagtcgttttaggaaaa
ggcacttatgggatagtttatgcaggtcgagatctgagcaaccaagtcagaatcgccatt
aaggaaatcccagagagagacagcagatactcccagcccctgcatgaagaaatagccttg
cataagcatctgaagcacaaaaatattgtccagtatctgggctctttcagtgaaaatggt
ttcattaaaatcttcatggagcaggtcccaggaggaagtctttctgctctccttcgttcc
aaatggggcccactgaaagacaatgagcaaacaatcggcttttatacaaagcaaatcctg
gaaggattaaaatacctccatgacaatcagatagttcaccgggatataaagggtgacaat
gtgttgattaatacctatagtggtgttctcaagatttctgatttcggaacatcaaagagg
cttgctggcataaatccatgtactgaaacttttactggtaccctccagtatatggcacca
gaaataatagataaaggaccaagaggctatggaaaggcagcagacatttggtctctgggc
tgcacaatcattgaaatggccactggaaaaccacccttttatgaactgggggaaccacaa
gcagctatgttcaaggtggggatgtttaaagtccacccagagatcccagagtccatgtca
gcagaggccaaggcattcatattgaagtgtttcgaaccagaccctgacaaaagagactgt
gctaacgacttgcttatggatgagttcttaaaagtttcaagcaaaaagaaaaagacacag
cctaagctttcagctctttcagctggatcgaatgagtacctcaggagtatctccttgcca
gtgccagtcctggtggaggacacaagcagcagcagcgagtacggctcagtttcccccgac
acagagttaaaggtggaccccttctctttcaaaacaagagccaagtcctgtggagaaaag
gatgtcaaaggcatacggacgttgtttctgggcatccctgatgaaaattttgaagaccac
agtgctccaccttctccagaagaaaaagattctggattctttatgctgaggaaggacagt
gagagacgggccacgcttcacaggattctgacggaagaccaggacaaagttgtgagaaac
ttaatggaatccttggctcagggggccgaagagcctaaactaaaatgggaacacatcaca
actctcgtcacaagcctcagagaatttgtgaggtccacagaccggaagatcatagccacc
accctgtctaagctgaagctggagctggactttgacagccatgggatcagtcaggtccag
gtggtgctctttggttttcaagatgctgtcaataaagttcttcggaatcataacatcaag
ccacactggatgtttgctttagacagtatcatccgaaaggcggtacagacagctattacc
attctggttccagaactgaggccacatttcagccttgcatctgagagtgatactgctgat
caagaagacttggatgcagaaggtgaccatgatgaacggccttcaaatcaaactgtccga
agacctcatgcagtccttgaagacgcggtggccacctcaggggtgagcacgctcagttct
actgtatcccatgactcccagagtgctcaccgatcactgaatgtacaacttggaaggatg
aaaatagaaacaaatagattactggaagaattggttcagaaagagaaagaattacaagca
ctccttcatcaagctattgaagagaaagaccaagaaattaaacacctgaagcttaagtcc
caaccaatagatattcctgggttgcctgcgtgtcactccagttctcctggcacaaacact
gaagattctgaacttactgactggctgagagaaaacggagccgatgaagacactataagt
cggtttttggctgaggattattcattaatggatgttctctactatgttacacgtgatgat
ttaaaatgcctgagactaaggggcgggatgctgtgcacactgtggaaagccatcactgac
ttccgagacaaacaggcttga
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integrated database retrieval system
