KEGG   Ovis canadensis (bighorn sheep): 138446299
Entry
138446299         CDS       T11679                                 
Name
(RefSeq) cytochrome P450 11B1, mitochondrial-like
  KO
K00497  steroid 11beta-monooxygenase [EC:1.14.15.4]
Organism
ocan  Ovis canadensis (bighorn sheep)
Pathway
ocan00140  Steroid hormone biosynthesis
ocan01100  Metabolic pathways
ocan04927  Cortisol synthesis and secretion
ocan04934  Cushing syndrome
Module
ocan_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:ocan00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    138446299
 09150 Organismal Systems
  09152 Endocrine system
   04927 Cortisol synthesis and secretion
    138446299
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    138446299
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ocan00199]
    138446299
Enzymes [BR:ocan01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.4  steroid 11beta-monooxygenase
     138446299
Cytochrome P450 [BR:ocan00199]
 Cytochrome P450, animal type
  CYP11 family
   138446299
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 138446299
NCBI-ProteinID: XP_069457257
LinkDB
Position
9:complement(24643516..24649277)
AA seq 531 aa
MALWAKVRLRMAGPWLSLHRARPLGTRATAAPKAVLPFEAMPRCPGNKWMRVLQIWKEQG
SENMHLDMHQTFQELGPIFRYDVGGRHMVFVMLPEDVERLQQAESLHPQRMLLEPWLAYR
QARGHKCGVFLLNGPQWRLDRLRLNPDVLSLPALQKYTPLVDGVARDFSQTLKARVLQNA
RGSLTLDIAPSVFRYTIEASTLVLYGERLGLLTQQPNPDSLNFIHALEAMFKSTVQLMFV
PRRLSRWTSSSMWREHFEAWDYIFQYANRAIQRIYQELALGHPWHYSGIVAELLMRADMT
LDTIKANTIDVTAGSVDTTAFPLLMTLFELARNPEVQQTLRQESLVAEAWISENPQRATT
ELPLLRAALKETLRLYPVGITLEWHVSSDLVLQNYHIPAGTLVKVLLYSLGRNPAVFARP
ESYHPQRWLDRQGSGSRFPHLAFGFGVRQRPSSSQVGSIWRNVPSLLGSQAPQWETARVL
QKVSDGTTQGDAQSPWQLCLSSFHRIAKHTLDFRHPRLNTRAGSVSQGHVV
NT seq 1596 nt   +upstreamnt  +downstreamnt
atggcgctgtgggcaaaggtcaggctgcggatggcaggaccctggctgtccctgcacagg
gcacgcccactgggcaccagagccactgcagcccccaaggcggtgctgcccttcgaagcc
atgccccggtgtcctggcaacaagtggatgcgggtgctgcagatctggaaggagcagggc
tctgagaacatgcacttggacatgcatcagaccttccaggagctggggcccattttcagg
tacgacgtgggagggagacacatggtgttcgtgatgctgcccgaggatgtggagaggctg
cagcaggcggagagccttcacccccagcggatgctcctggagccctggctggcctaccga
caggctcgcgggcacaagtgtggcgtgttcttgctcaacgggccccagtggcgtttggac
cgactgcggctgaacccagacgtgctctcgctgccagccctgcagaagtacacgcccttg
gtggatggcgtggccagggacttctcccagaccctgaaggcaagggtgctacagaatgct
cgggggagtctgaccctggacatcgcgcccagcgtcttccgctacaccatcgaagccagc
accttagtcctttacggagagcggcttggccttctgacccagcaaccaaaccctgacagc
ctgaactttatccacgcgctggaggccatgttcaagtccaccgtgcagctcatgtttgtg
ccccggcgcctgtcacggtggacgagcagcagcatgtggagggagcattttgaggcctgg
gactacatcttccagtatgccaacagagccatccagagaatctatcaggagctggccctc
ggccacccgtggcactacagcggcattgtggcagagctgctgatgcgagcagacatgacc
ctggataccatcaaggccaacacaatcgacgtcactgctgggagtgtggacacgacagcc
ttccccttgctgatgactctctttgagctggctcggaacccggaggtacagcagaccctg
cgccaggagagcctggtggctgaggcctggatctcagaaaatccccagagggccaccacg
gagctgcctttgttgcgggcggccctcaaggagaccttgaggctctaccccgtgggtatc
actttggagtggcacgtgagctcggacctggtgctgcagaactaccacatcccggccggg
acgctggtgaaggtcctactctattccctgggtcgaaaccccgccgtgttcgccaggccc
gagagctatcacccccagcgctggctggaccgccagggctctggaagcaggttcccgcac
ctggcctttggctttggagtgcgccagaggccctcatcctcccaagtaggcagcatctgg
agaaacgttccgtcactcttaggaagccaggcgccacagtgggagacggctcgagtcctg
cagaaggtgtctgacggcaccacgcagggcgatgcacagtctccgtggcagctctgcctg
tcctcattccaccgcatcgccaagcacactctcgacttccgccacccccgcctgaacacc
cgtgcaggctcggtgtctcaggggcatgtggtctga

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