KEGG   Oryctolagus cuniculus (rabbit): 100008645
Entry
100008645         CDS       T03373                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein
  KO
K13375  transforming growth factor beta-1
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04010  MAPK signaling pathway
ocu04060  Cytokine-cytokine receptor interaction
ocu04068  FoxO signaling pathway
ocu04110  Cell cycle
ocu04148  Efferocytosis
ocu04218  Cellular senescence
ocu04350  TGF-beta signaling pathway
ocu04380  Osteoclast differentiation
ocu04390  Hippo signaling pathway
ocu04659  Th17 cell differentiation
ocu04672  Intestinal immune network for IgA production
ocu04926  Relaxin signaling pathway
ocu04932  Non-alcoholic fatty liver disease
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu05140  Leishmaniasis
ocu05142  Chagas disease
ocu05144  Malaria
ocu05145  Toxoplasmosis
ocu05146  Amoebiasis
ocu05152  Tuberculosis
ocu05161  Hepatitis B
ocu05166  Human T-cell leukemia virus 1 infection
ocu05200  Pathways in cancer
ocu05205  Proteoglycans in cancer
ocu05210  Colorectal cancer
ocu05211  Renal cell carcinoma
ocu05212  Pancreatic cancer
ocu05220  Chronic myeloid leukemia
ocu05225  Hepatocellular carcinoma
ocu05226  Gastric cancer
ocu05321  Inflammatory bowel disease
ocu05323  Rheumatoid arthritis
ocu05410  Hypertrophic cardiomyopathy
ocu05414  Dilated cardiomyopathy
ocu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100008645 (TGFB1)
   04350 TGF-beta signaling pathway
    100008645 (TGFB1)
   04390 Hippo signaling pathway
    100008645 (TGFB1)
   04068 FoxO signaling pathway
    100008645 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100008645 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100008645 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    100008645 (TGFB1)
   04218 Cellular senescence
    100008645 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    100008645 (TGFB1)
   04672 Intestinal immune network for IgA production
    100008645 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    100008645 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100008645 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100008645 (TGFB1)
   05205 Proteoglycans in cancer
    100008645 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100008645 (TGFB1)
   05212 Pancreatic cancer
    100008645 (TGFB1)
   05225 Hepatocellular carcinoma
    100008645 (TGFB1)
   05226 Gastric cancer
    100008645 (TGFB1)
   05220 Chronic myeloid leukemia
    100008645 (TGFB1)
   05211 Renal cell carcinoma
    100008645 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100008645 (TGFB1)
   05161 Hepatitis B
    100008645 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100008645 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100008645 (TGFB1)
   05144 Malaria
    100008645 (TGFB1)
   05145 Toxoplasmosis
    100008645 (TGFB1)
   05140 Leishmaniasis
    100008645 (TGFB1)
   05142 Chagas disease
    100008645 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    100008645 (TGFB1)
   05321 Inflammatory bowel disease
    100008645 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100008645 (TGFB1)
   05414 Dilated cardiomyopathy
    100008645 (TGFB1)
   05415 Diabetic cardiomyopathy
    100008645 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100008645 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100008645 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:ocu03110]
    100008645 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ocu04052]
    100008645 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:ocu00536]
    100008645 (TGFB1)
Chaperones and folding catalysts [BR:ocu03110]
 Intramolecular chaperones
  Others
   100008645 (TGFB1)
Cytokines and neuropeptides [BR:ocu04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   100008645 (TGFB1)
Glycosaminoglycan binding proteins [BR:ocu00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   100008645 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 100008645
NCBI-ProteinID: XP_051692327
UniProt: G1SV95
LinkDB
Position
Unknown
AA seq 387 aa
MLPSGMRLLLPLLWLLVLSPARPAVGTLSRNNTHMELLRQQHIQAVGALILAKLGLSSPP
SDDEVPTGPVPEDILALYNRTRDQVSGERAKQKPQPDSGFFGKEITSVPMLDSNHEIYQK
YKESRHSVYMFFNTSELRQAVPKPVLLSHAELRLQVLKLQQEQQVELYQKCSNDSWRYHR
RRKLTPSDTDEWLSFTVTWIVRQWLRGGEEIEGFRLSAHCSCDNKDNVLQVDINGISSGR
RGDLATIHSMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYIDFR
KDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEP
LPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1164 nt   +upstreamnt  +downstreamnt
atgctgccctccgggatgcgactgctgctgcctctgctgtggctcctggtgctgtcaccc
gcccgcccagccgtgggaacgctcagccgcaacaacacccacatggagctgctcagacaa
cagcacatccaggccgtcggcgccctgatcctggccaagctggggctctccagcccccca
agtgatgatgaggtgccgacgggtccggtgcccgaggacatactcgccctgtacaacaga
acccgcgatcaggtgtccggggagagagctaaacagaagccccaacccgactcaggcttc
tttggcaaggagatcaccagtgtgccaatgctggacagcaaccacgaaatctaccaaaaa
tacaaagaaagtcggcacagcgtctatatgttcttcaacacgtcagagctccggcaagca
gtgcccaagccggtgttgctgtcccatgcagagctgcgcctgcaagtgctcaagttacag
caggagcagcaggtggagctgtaccagaaatgcagcaacgattcctggcgctaccacagg
aggcgtaagctgacacccagtgacacagatgagtggttgtcatttaccgtcacctggatt
gtgcggcagtggctgagaggtggagaggaaatagagggcttccgcctcagcgcccactgt
tcctgtgacaacaaagataatgtcctccaagtggacatcaacgggatcagttccggccgt
cgaggtgacctggccaccattcacagcatgaaccgacccttcctgctcctcatggccacc
cctctggaacgggctcaacatctacacagttcccggcaccgccgagccctggacaccaac
tactgcttcagctccacagagaagaactgctgtgtgcggcagctgtacattgacttccgc
aaggacctgggctggaagtggatccacgagcccaagggctaccacgccaacttctgcctg
ggaccctgcccctacatctggagcctggacacccagtacagcaaggtcctggccctgtac
aaccagcacaacccgggcgcgtcggcagcgccgtgctgtgtgccacaggcgctggagcca
ctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctgtccaacatgatc
gtgcgctcctgcaagtgcagctga

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