Oryctolagus cuniculus (rabbit): 100009000
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Entry
100009000 CDS
T03373
Symbol
MMP2
Name
(RefSeq) 72 kDa type IV collagenase precursor
KO
K01398
matrix metalloproteinase-2 (gelatinase A) [EC:
3.4.24.24
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu01522
Endocrine resistance
ocu04670
Leukocyte transendothelial migration
ocu04912
GnRH signaling pathway
ocu04915
Estrogen signaling pathway
ocu04926
Relaxin signaling pathway
ocu04933
AGE-RAGE signaling pathway in diabetic complications
ocu05200
Pathways in cancer
ocu05205
Proteoglycans in cancer
ocu05219
Bladder cancer
ocu05415
Diabetic cardiomyopathy
ocu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
100009000 (MMP2)
09152 Endocrine system
04912 GnRH signaling pathway
100009000 (MMP2)
04915 Estrogen signaling pathway
100009000 (MMP2)
04926 Relaxin signaling pathway
100009000 (MMP2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100009000 (MMP2)
05205 Proteoglycans in cancer
100009000 (MMP2)
09162 Cancer: specific types
05219 Bladder cancer
100009000 (MMP2)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100009000 (MMP2)
05415 Diabetic cardiomyopathy
100009000 (MMP2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100009000 (MMP2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100009000 (MMP2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
ocu01002
]
100009000 (MMP2)
Enzymes [BR:
ocu01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.24 gelatinase A
100009000 (MMP2)
Peptidases and inhibitors [BR:
ocu01002
]
Metallo peptidases
Family M10
100009000 (MMP2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M10
fn2
Hemopexin
PG_binding_1
Reprolysin_3
Reprolysin_5
Peptidase_M66
Reprolysin_4
Motif
Other DBs
NCBI-GeneID:
100009000
NCBI-ProteinID:
NP_001075678
Ensembl:
ENSOCUG00000006714
UniProt:
P50757
LinkDB
All DBs
Position
5:11744230..11769594
Genome browser
AA seq
662 aa
AA seq
DB search
MEALGARGALAGFLRALCVLGCLLGRATAPPSPVIKFPGDVAPKTDKELAVQYLNTFYGC
PKDSCNLFVLKDTLKKMQKFFGLPQTGELDQSTIETMRKPRCGNPDVANYNFFPRKPKWD
KNQITYRIIGYTPDLDPETVDDAFARAFQVWSNVTPLRFSRIHDGEADIMINFGRWEHGD
GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFN
GKEYTSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNADGQPCKFPFRFQGT
SYSSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTIGGNSEGAPCVFPFTFLGNKY
ESCTSAGRSDGKMWCATSTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGAL
MAPIYTYTKNFRLSQDDIKGIQELYGASPDAGTDAGTGPTPTLGPVTPEICTQDIVFDGI
AQIRGEIFFFKDRFIWRTVTPGDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGN
EYWVYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKM
DPGFPRLIADAWNAIPDHLDAVVDLQGSGHSYFFKGTYYLKLENQSLKSVKVGSIKTDWL
GC
NT seq
1989 nt
NT seq
+upstream
nt +downstream
nt
atggaggcgctaggggcccggggcgcgctcgccggcttcctgcgggcgctctgcgtcctg
ggctgcctgctgggccgcgccaccgccccgccgtctcccgtcatcaaattccccggcgat
gtcgcccccaaaacggacaaagagctggcggtgcaatacctgaacaccttctacggctgc
cccaaggacagttgcaacctgttcgtgctgaaggacaccctcaagaagatgcagaagttc
ttcgggctgccccagacaggtgaactggaccagagcaccatcgagaccatgcggaagccg
cgctgcggcaacccggatgtggccaactataacttcttcccccgcaagcccaagtgggac
aagaatcagatcacatacaggatcatcggctacacgcctgacctcgacccggaaacagtg
gatgatgccttcgcgcgcgccttccaagtctggagtaacgtgaccccgctgcggttttct
cgaatccacgatggagaagctgacatcatgatcaactttggccgctgggagcatggagac
ggatacccgtttgacggcaaggacgggctcctggctcatgcctttgctccgggcactggt
gttgggggagattcccactttgatgatgatgagctgtggaccctgggagaaggtcaagtg
gtccgtgtgaagtatggcaatgccgatggggagtactgcaagttccccttcctgttcaat
ggcaaggagtacaccagctgcacagacaccggtcgcagcgatggcttcctctggtgctcc
accacctacaactttgagaaggatggcaagtacggcttctgcccccatgaagccctgttc
accatgggtggcaacgccgatgggcagccctgcaagttcccgttccgcttccaaggcaca
tcctacagcagctgcaccacggaaggccgcaccgacggctaccgctggtgcggcaccacc
gaggactacgaccgcgacaagaagtatggcttctgccccgagactgccatgtctactatt
ggcgggaactcggaaggcgccccctgtgtcttccccttcaccttcctgggcaacaagtat
gagagctgtaccagcgccggccgcagtgatggcaagatgtggtgcgcgacctcaaccaac
tacgacgatgaccgcaagtggggcttctgccctgaccaaggttacagcctgttcctcgtg
gcagcccatgagtttggccacgccatggggctggagcactcccaggaccccggggccctg
atggcgcccatttacacctacacgaagaacttccgcctgtcacaggatgacatcaagggc
attcaagagctctacggggcctctcccgacgctggcacggacgctggcaccggccccacg
cctacgctgggacctgtcactcctgagatctgcacacaggacatcgtcttcgatggcatc
gctcagatccgtggggagatcttcttcttcaaggaccggttcatttggcggacggtgaca
ccgggtgacaagcccatgggacccctgctggtggccaccttctggcctgagctcccggag
aagatcgacgctgtgtacgaggccccccaggaggagaaggccgtgttctttgcaggcaat
gaatactgggtgtattcagccagcaccctggagcgagggtaccccaagcctctgaccagc
ctcgggctgccccccgatgtccagcgagtagacgcggccttcaactggagcaagaacaag
aagacgtacatctttgctggagacaagttctggagatacaatgaggtgaagaagaagatg
gaccctggcttccctcggctcatcgcggatgcctggaacgccatccccgatcacctggat
gctgtggtggacctgcagggcagcggtcacagctacttcttcaagggcacttattacctg
aagctcgagaaccaaagtctgaagagcgtgaaggttggaagcatcaagacggactggctg
ggctgctga
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