KEGG   Oryctolagus cuniculus (rabbit): 100009039
Entry
100009039         CDS       T03373                                 
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu01522  Endocrine resistance
ocu04110  Cell cycle
ocu04115  p53 signaling pathway
ocu04151  PI3K-Akt signaling pathway
ocu04218  Cellular senescence
ocu04530  Tight junction
ocu04660  T cell receptor signaling pathway
ocu04933  AGE-RAGE signaling pathway in diabetic complications
ocu04934  Cushing syndrome
ocu05160  Hepatitis C
ocu05162  Measles
ocu05163  Human cytomegalovirus infection
ocu05164  Influenza A
ocu05165  Human papillomavirus infection
ocu05166  Human T-cell leukemia virus 1 infection
ocu05167  Kaposi sarcoma-associated herpesvirus infection
ocu05169  Epstein-Barr virus infection
ocu05200  Pathways in cancer
ocu05203  Viral carcinogenesis
ocu05212  Pancreatic cancer
ocu05214  Glioma
ocu05218  Melanoma
ocu05219  Bladder cancer
ocu05220  Chronic myeloid leukemia
ocu05222  Small cell lung cancer
ocu05223  Non-small cell lung cancer
ocu05224  Breast cancer
ocu05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    100009039
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100009039
   04115 p53 signaling pathway
    100009039
   04218 Cellular senescence
    100009039
  09144 Cellular community - eukaryotes
   04530 Tight junction
    100009039
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    100009039
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100009039
   05203 Viral carcinogenesis
    100009039
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100009039
   05225 Hepatocellular carcinoma
    100009039
   05214 Glioma
    100009039
   05220 Chronic myeloid leukemia
    100009039
   05218 Melanoma
    100009039
   05219 Bladder cancer
    100009039
   05224 Breast cancer
    100009039
   05222 Small cell lung cancer
    100009039
   05223 Non-small cell lung cancer
    100009039
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100009039
   05160 Hepatitis C
    100009039
   05164 Influenza A
    100009039
   05162 Measles
    100009039
   05163 Human cytomegalovirus infection
    100009039
   05167 Kaposi sarcoma-associated herpesvirus infection
    100009039
   05169 Epstein-Barr virus infection
    100009039
   05165 Human papillomavirus infection
    100009039
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100009039
   04934 Cushing syndrome
    100009039
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100009039
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100009039
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     100009039
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: CMGC group
  CDK family
   100009039
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo Haspin_kinase ABC1 Kinase-like
Other DBs
NCBI-GeneID: 100009039
NCBI-ProteinID: XP_002720970
UniProt: G1T3E1
LinkDB
Position
Unknown
AA seq 303 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSSGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSAGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRAAFSPRGPRPVQSVVPELEESGAQLLLEMLTFSPHKRISACRALQHSYLHKEEG
GPE
NT seq 912 nt   +upstreamnt  +downstreamnt
atggctacctctcgctacgagcctgtagctgaaattggtgtcggtgcctacgggacggtg
tacaaggcccgggacccccacagtggccactttgtggccctcaagagcgtgcgagtcccc
aatggaggaggcgctggagggggccttcccatcagcactgttcgcgaggtggctttactc
aggcggctggaggcctttgagcaccccaatgttgtccggctgatggacgtctgtgccacc
tcccgaaccgaccgggaaatcaaggtgaccctggtgtttgagcacgtcgaccaagaccta
aggacgtatctggacaaggcacccccaccaggcctgccggcagagaccatcaaggatctg
atgcgccagtttcttagaggcctggatttccttcatgccaattgcatcgtccaccgagac
ctgaagccagagaatattctggtgacgagcagcgggacggtcaagctggctgacttcggc
ctggctagaatctacagctaccagatggcgcttacacctgtggttgtgacgctctggtac
cgtgctcctgaggttcttctgcagtctacatatgccacgcctgtggacatgtggagcgct
ggctgtatctttgcagaaatgtttcgtcgaaagcctctcttctgtggaaactccgaagcc
gaccagctgggcaaaatctttgacctgatcgggctgcctccggaagacgactggccccga
gatgtgtcgctcccccgagcggccttctccccaagagggccccgcccagtgcagtcggtg
gtgccggagctggaggagtccggagcgcagctgctgctggaaatgctgactttcagccca
cacaagcggatctctgcctgcagagccctgcagcactcttacctccacaaggaagaaggc
ggcccagagtga

KEGG   Oryctolagus cuniculus (rabbit): 100009040
Entry
100009040         CDS       T03373                                 
Name
(RefSeq) cyclin-dependent kinase 6 isoform X1
  KO
K02091  cyclin-dependent kinase 6 [EC:2.7.11.22]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04110  Cell cycle
ocu04115  p53 signaling pathway
ocu04151  PI3K-Akt signaling pathway
ocu04218  Cellular senescence
ocu04934  Cushing syndrome
ocu05160  Hepatitis C
ocu05162  Measles
ocu05163  Human cytomegalovirus infection
ocu05164  Influenza A
ocu05165  Human papillomavirus infection
ocu05167  Kaposi sarcoma-associated herpesvirus infection
ocu05169  Epstein-Barr virus infection
ocu05200  Pathways in cancer
ocu05203  Viral carcinogenesis
ocu05206  MicroRNAs in cancer
ocu05212  Pancreatic cancer
ocu05214  Glioma
ocu05218  Melanoma
ocu05220  Chronic myeloid leukemia
ocu05222  Small cell lung cancer
ocu05223  Non-small cell lung cancer
ocu05224  Breast cancer
ocu05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    100009040
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100009040
   04115 p53 signaling pathway
    100009040
   04218 Cellular senescence
    100009040
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100009040
   05206 MicroRNAs in cancer
    100009040
   05203 Viral carcinogenesis
    100009040
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100009040
   05225 Hepatocellular carcinoma
    100009040
   05214 Glioma
    100009040
   05220 Chronic myeloid leukemia
    100009040
   05218 Melanoma
    100009040
   05224 Breast cancer
    100009040
   05222 Small cell lung cancer
    100009040
   05223 Non-small cell lung cancer
    100009040
  09172 Infectious disease: viral
   05160 Hepatitis C
    100009040
   05164 Influenza A
    100009040
   05162 Measles
    100009040
   05163 Human cytomegalovirus infection
    100009040
   05167 Kaposi sarcoma-associated herpesvirus infection
    100009040
   05169 Epstein-Barr virus infection
    100009040
   05165 Human papillomavirus infection
    100009040
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100009040
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100009040
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     100009040
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: CMGC group
  CDK family
   100009040
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH Haspin_kinase RIO1 Kinase-like FTA2 Uricase
Other DBs
NCBI-GeneID: 100009040
NCBI-ProteinID: XP_002713851
Ensembl: ENSOCUG00000011078
UniProt: G1T0K2
LinkDB
Position
10:32997729..33231767
AA seq 326 aa
MEKDGLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALAHPYF
QDLERGKESLDPHLPPSQSASELNTA
NT seq 981 nt   +upstreamnt  +downstreamnt
atggagaaggacggcctgagccgcgccgaccagcagtacgagtgcgtggcggagatcggg
gagggcgcctacgggaaggtgttcaaggcccgcgacctcaagaacggaggccggttcgtg
gcgctgaagcgcgtgcgggtgcagacgggcgaggaaggcatgccgctctccaccatccgc
gaggtggcggtgctgaggcacctggagaccttcgagcaccccaacgtggtcaggctgttc
gatgtatgcacagtgtcccggacagacagagagacaaagctaacactagtgtttgaacat
gttgatcaagacttgaccacttacctggataaagttccggagcctggagtgcccactgaa
actataaaggatatgatgtttcagctcctgcgaggtctggactttcttcattctcaccga
gtagtgcatcgtgatctaaaaccacagaacattctggtgaccagcagtggacaaataaaa
ctggctgacttcggccttgcgcgcatctacagttttcagatggctcttacttcagtggtc
gtcacgctgtggtaccgagctccagaagtcctgctgcagtccagctacgccacgcccgtg
gatctctggagtgtcggctgcatatttgcagaaatgtttcgtagaaagcctctctttcgt
ggaagttcagatgtggatcagctaggaaaaatcttggacgtcattggactcccaggagaa
gaggactggcccagagatgttgcccttcccaggcaagcgtttcattccaaatctgcccag
ccgattgagaagttcgtaacagatatcgatgaactaggcaaagacctgcttctgaagtgc
ttgaccttcaatccagccaaaagaatatctgcctacagcgccctggcccacccgtacttc
caagacctggagaggggcaaggagagcttggatccccacctaccgcccagccagagcgcc
tcagagctgaacacagcctga

KEGG   Oryctolagus cuniculus (rabbit): 100134865
Entry
100134865         CDS       T03373                                 
Name
(RefSeq) cyclin-dependent kinase 2 isoform X2
  KO
K02206  cyclin-dependent kinase 2 [EC:2.7.11.22]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu04068  FoxO signaling pathway
ocu04110  Cell cycle
ocu04114  Oocyte meiosis
ocu04115  p53 signaling pathway
ocu04151  PI3K-Akt signaling pathway
ocu04218  Cellular senescence
ocu04914  Progesterone-mediated oocyte maturation
ocu04934  Cushing syndrome
ocu05160  Hepatitis C
ocu05161  Hepatitis B
ocu05162  Measles
ocu05165  Human papillomavirus infection
ocu05166  Human T-cell leukemia virus 1 infection
ocu05169  Epstein-Barr virus infection
ocu05200  Pathways in cancer
ocu05203  Viral carcinogenesis
ocu05215  Prostate cancer
ocu05222  Small cell lung cancer
ocu05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    100134865
   04151 PI3K-Akt signaling pathway
    100134865
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100134865
   04114 Oocyte meiosis
    100134865
   04115 p53 signaling pathway
    100134865
   04218 Cellular senescence
    100134865
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    100134865
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100134865
   05203 Viral carcinogenesis
    100134865
  09162 Cancer: specific types
   05226 Gastric cancer
    100134865
   05215 Prostate cancer
    100134865
   05222 Small cell lung cancer
    100134865
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100134865
   05161 Hepatitis B
    100134865
   05160 Hepatitis C
    100134865
   05162 Measles
    100134865
   05169 Epstein-Barr virus infection
    100134865
   05165 Human papillomavirus infection
    100134865
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100134865
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ocu01001]
    100134865
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:ocu03032]
    100134865
   03036 Chromosome and associated proteins [BR:ocu03036]
    100134865
Enzymes [BR:ocu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     100134865
Protein kinases [BR:ocu01001]
 Serine/threonine kinases: CMGC group
  CDK family
   100134865
DNA replication proteins [BR:ocu03032]
 Eukaryotic type
  DNA Replication Initiation Factors
   CDK (cyclin dependent kinase)
    100134865
Chromosome and associated proteins [BR:ocu03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    100134865
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 100134865
NCBI-ProteinID: XP_002711107
Ensembl: ENSOCUG00000000998
UniProt: A0A5F9C2I2
LinkDB
Position
4:47083916..47090109
AA seq 298 aa
MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
NT seq 897 nt   +upstreamnt  +downstreamnt
atggagaacttccaaaaggtggaaaagatcggagagggcacgtacggagtggtgtacaaa
gccaaaaacaagctgacgggagaagtggtggcgctcaagaaaatccgcctggacactgag
actgaaggtgtacccagcactgccatccgggagatctctctgcttaaggagcttaaccac
cccaatattgtcaagctgctggatgtcatccacacggaaaacaaactttacctcgttttt
gaattcctgcaccaagatctcaagaaattcatggatgcctctgctctcactggcattcct
cttcccctcatcaagagctatctgttccagctgctccaaggcctagcgttctgccattct
catcgggtcctgcaccgagatctaaaacctcagaatctacttatcaatgcagagggctcc
atcaagttagccgactttggactagccagagcctttggagtgcctgttcgtacttacacc
cacgaggtggtgaccctgtggtaccgagcccctgagatcctcctgggctgcaaatactac
tccacagccgtggacatctggagcctgggctgcatctttgccgagatggtgacccgccgg
gccctgttccctggtgattctgagattgaccagctcttccggatcttccggactctgggg
accccagatgaggtggtttggccaggagttacttcaatgcccgattacaagccgagtttc
cccaagtgggcccggcaggattttagcaaagtcgtgcctcccctggatgaagatggacgg
agcttgttatcgcaaatgttgcactatgaccccaacaagcggatttcggcaaaggcagct
ctggctcaccccttcttccaggatgtgaccaagccagtaccccatctccgactctaa

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