KEGG   Oryctolagus cuniculus (rabbit): 100337882
Entry
100337882         CDS       T03373                                 
Name
(RefSeq) adenylate cyclase type 8 isoform X1
  KO
K08048  adenylate cyclase 8 [EC:4.6.1.1]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu00230  Purine metabolism
ocu01100  Metabolic pathways
ocu01522  Endocrine resistance
ocu04015  Rap1 signaling pathway
ocu04020  Calcium signaling pathway
ocu04022  cGMP-PKG signaling pathway
ocu04024  cAMP signaling pathway
ocu04062  Chemokine signaling pathway
ocu04072  Phospholipase D signaling pathway
ocu04081  Hormone signaling
ocu04082  Neuroactive ligand signaling
ocu04114  Oocyte meiosis
ocu04211  Longevity regulating pathway
ocu04213  Longevity regulating pathway - multiple species
ocu04261  Adrenergic signaling in cardiomyocytes
ocu04270  Vascular smooth muscle contraction
ocu04371  Apelin signaling pathway
ocu04540  Gap junction
ocu04611  Platelet activation
ocu04713  Circadian entrainment
ocu04714  Thermogenesis
ocu04720  Long-term potentiation
ocu04723  Retrograde endocannabinoid signaling
ocu04724  Glutamatergic synapse
ocu04725  Cholinergic synapse
ocu04727  GABAergic synapse
ocu04742  Taste transduction
ocu04750  Inflammatory mediator regulation of TRP channels
ocu04911  Insulin secretion
ocu04912  GnRH signaling pathway
ocu04913  Ovarian steroidogenesis
ocu04914  Progesterone-mediated oocyte maturation
ocu04915  Estrogen signaling pathway
ocu04916  Melanogenesis
ocu04918  Thyroid hormone synthesis
ocu04921  Oxytocin signaling pathway
ocu04923  Regulation of lipolysis in adipocytes
ocu04925  Aldosterone synthesis and secretion
ocu04926  Relaxin signaling pathway
ocu04927  Cortisol synthesis and secretion
ocu04928  Parathyroid hormone synthesis, secretion and action
ocu04934  Cushing syndrome
ocu04935  Growth hormone synthesis, secretion and action
ocu04970  Salivary secretion
ocu04971  Gastric acid secretion
ocu04972  Pancreatic secretion
ocu04976  Bile secretion
ocu05032  Morphine addiction
ocu05163  Human cytomegalovirus infection
ocu05166  Human T-cell leukemia virus 1 infection
ocu05200  Pathways in cancer
ocu05207  Chemical carcinogenesis - receptor activation
ocu05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    100337882
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    100337882
   04072 Phospholipase D signaling pathway
    100337882
   04024 cAMP signaling pathway
    100337882
   04022 cGMP-PKG signaling pathway
    100337882
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    100337882
   04081 Hormone signaling
    100337882
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100337882
   04062 Chemokine signaling pathway
    100337882
  09152 Endocrine system
   04911 Insulin secretion
    100337882
   04923 Regulation of lipolysis in adipocytes
    100337882
   04913 Ovarian steroidogenesis
    100337882
   04915 Estrogen signaling pathway
    100337882
   04921 Oxytocin signaling pathway
    100337882
   04926 Relaxin signaling pathway
    100337882
   04935 Growth hormone synthesis, secretion and action
    100337882
   04918 Thyroid hormone synthesis
    100337882
   04928 Parathyroid hormone synthesis, secretion and action
    100337882
   04925 Aldosterone synthesis and secretion
    100337882
   04927 Cortisol synthesis and secretion
    100337882
  09154 Digestive system
   04970 Salivary secretion
    100337882
   04971 Gastric acid secretion
    100337882
   04972 Pancreatic secretion
    100337882
   04976 Bile secretion
    100337882
  09156 Nervous system
   04724 Glutamatergic synapse
    100337882
   04727 GABAergic synapse
    100337882
   04725 Cholinergic synapse
    100337882
   04720 Long-term potentiation
    100337882
   04723 Retrograde endocannabinoid signaling
    100337882
  09157 Sensory system
   04742 Taste transduction
    100337882
   04750 Inflammatory mediator regulation of TRP channels
    100337882
  09149 Aging
   04211 Longevity regulating pathway
    100337882
   04213 Longevity regulating pathway - multiple species
    100337882
  09159 Environmental adaptation
   04713 Circadian entrainment
    100337882
   04714 Thermogenesis
    100337882
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100337882
   05207 Chemical carcinogenesis - receptor activation
    100337882
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100337882
   05163 Human cytomegalovirus infection
    100337882
  09165 Substance dependence
   05032 Morphine addiction
    100337882
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    100337882
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    100337882
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100337882
Enzymes [BR:ocu01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     100337882
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom TBK1_ULD
Other DBs
NCBI-GeneID: 100337882
NCBI-ProteinID: XP_002710595
Ensembl: ENSOCUG00000002685
UniProt: G1SI32
LinkDB
Position
3:complement(146186784..146437476)
AA seq 1251 aa
MELSDVRFLSGSEELYTIHPTPPAGDGGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGG
GSGGSGKGSNPAGCGPNHHAPQLSGESALPLYSLGPGERAHSTGGSKVFPERSGSGSASG
SGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRK
SEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHT
YLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTS
LLQVVLQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEAR
LRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADV
KGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAH
CCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKL
ESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPED
IVKESVSPSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHV
QSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAF
IVLLFITTIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINE
NYLARNVIIFASILINFLGAVLNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTG
VLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNLNHSGEDFLGTKEA
SLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVA
RHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDE
LLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKH
SFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLIL
KDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLV
QSLNRQRQKQLLNENNNTGIIKGHYNRRTLLTPTGPEPGAQAEGTDKSDLP
NT seq 3756 nt   +upstreamnt  +downstreamnt
atggagctctccgatgtgcgcttccttagcggcagcgaggaactctacaccatccacccg
acgcccccggccggcgacggcgggagcggctcccggccgcagcggctgctgtggcagacg
gcggtgcggcacatcaccgagcagcgtttcattcatgggcaccggggcggcggcggcggc
gggagcggaggctccgggaaaggctcgaaccctgcgggctgcggccccaaccaccacgca
cctcagctgtccggcgagtccgcgctgccgctctactcgctgggccccggggagcgggcg
cacagcaccggtggctccaaagtcttcccggaacgcagcgggagcggcagcgccagtggc
agcgggggtgggggtgacctgggcttcctgcaccttgactgcgccccgagcaactccgat
ttcttcctcaatgggggctatagctatcgaggggtcattttccccaccttgcgcaactcc
ttcaagtcccgggatctggaacgcctgtaccagcgctatttcctgggccaaaggcgcaag
tcggaggtggtgatgaacgtgctggatgtgctgaccaaactcaccctcctggttctgcac
ttgagcctggcctcagcacccatggacccgctcaaaggcatcctgttgggcttcttcact
ggcatcgaggtggtgatctgtgccctggtggtggtcaggaaggacaccacctcgcacacg
tacctgcagtacagcggcgtggtcacctgggtggccatgaccacccagatcctggcagca
ggtctcggctacgggctcctaggtgatggcataggctacgtgctcttcacgctcttcgcc
acgtacagcatgctgccgctgccgcttacctgggccattctggctggcctgggcacctcg
ctgctgcaggtggtcctccaagtggtcatccctcggctggcagtcatttccatcaaccag
gttgtggcccaggcagtgctattcatgtgtatgaacacggctggaatcttcatcagttac
ctctcagaccgggcccagcgtcaagccttcctggaaacgcggaggtgtgtggaggccagg
ctacgcctggagacagagaatcaaagacaggagcggctcgtgctgtctgtgctaccccga
tttgttgtcctggaaatgatcaacgacatgaccaatgtggaagatgagcacctgcagcac
cagttccatcgaatctacatccatcgttatgagaacgtcagtattctttttgcagatgtt
aaaggatttaccaacctctccacgaccttgtccgctcaggagctggtcaggatgctcaac
gagctctttgccagatttgatcgactggcccatgagcatcactgccttcgtattaaaatc
ctgggagactgctactactgtgtttccggactgcctgagccccgccaggaccatgcccac
tgctgtgttgaaatgggcctcagcatgatcaaaaccatcaggtatgtccggtcgaggaca
aagcatgatgtggatatgaggattggaatccactcgggctccgtgctatgtggtgtgctg
ggcctgaggaagtggcagtttgatgtctggtcttgggatgtggacattgcaaataaactg
gaatctggaggaatccctgggagaattcacatttccaaagccaccctggactgcctcaat
ggtgactataatgtggaagaaggccatggaaaagaacgaaatgagttcttgaggaagcat
aatatagagacctatttaattaagcagcctgaggagagtctgctctccctgccggaagac
atcgtcaaggaatcggtgagcccctctgacaggagaaacagtggggcaacattcactgaa
ggatcctggagccccgaactgccctttgataacattgtggggaagcagaatactctggct
gccctaacaagaaattcaataaatctgcttccaaaccatcttgcacaagctttgcatgtc
cagtctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagtggc
gataaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagcctg
gagcacaagtattctcaaatgagggatgaagtattcaagtcaaacttagtctgtgcattt
attgttcttctatttatcacgacaatacaaagtttgcttccttcttcaagagtgatgcca
atgaccatccagttctccattctgattatgctgcactcagctctggtcctgatcaccaca
gcagaggattataagtgtttgcccctggtcctgaggaaaacttgctgttggattaacgag
aactacttggcccggaacgtcatcatctttgcctccatcttgattaatttcctgggagcc
gtcctaaatatcctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttc
aattcctcagctgtgtttacagatatctgctcctacccagagtactttgtcttcaccgga
gtgttggccatggtgacctgtgcagtgttcctccgacttaactctgtcctgaagctagct
gtgctgctaatcatgatcgccatctatgccctgctgacagagaccatctacgctggcctc
tttctgcgttatgacaacttgaaccacagtggcgaagatttcctggggaccaaagaagca
tcactgttgctaatggccatgttcctccttgctgtattctaccacggacagcagctggag
tacacagcccgcctggacttcctctggcgagtacaggccaaggaggagatcaatgaaatg
aaggagctgagggaacacaatgagaacatgctccggaatatcttacccagccacgtggcc
cgacatttcctggagaaagaccgagacaatgaggaactgtactctcaatcctatgatgcc
gttggggtgatgtttgcctccatcccaggatttgcagacttttactctcagactgaaatg
aataaccagggagtggaatgcctacggttgctgaatgagatcattgctgacttcgatgag
ttgcttggtgaagaccggttccaggacattgaaaagatcaaaaccattggcagcacttac
atggccgtgtcaggcctgtcaccagaaaaacagcaatgtgaagacaagtggggacatttg
tgtgccctggccgacttctctctcgccctcactgaaagcatacaggagatcaacaagcat
tccttcaacaattttgaactccggatcggcatcagccatggctcagtggttgctggtgtg
attggcgctaagaaacctcaatatgacatttggggcaaaaccgtgaacctggccagccga
atggacagcacaggggtgagcggacggatccaagtgccagaggagacctatctcatcctc
aaggaccagggctttgcctttgactaccgaggggagatctacgtgaaaggcatcagtgaa
caggaagggaaaatcaaaacgtactttctcctgggaagagtccaacccaacccattcatc
ttgcccccaagaagactacccgggcagtactccttggctgcagtcgttctgggccttgtc
cagtccctcaaccggcaaaggcagaagcagctactcaatgagaacaacaacacggggatc
atcaaaggccattacaaccgacggactttgctgactcccactgggccggagcctggggcc
caagctgaaggcactgacaaatccgatttgccataa

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