Oryctolagus cuniculus (rabbit): 100340525
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Entry
100340525 CDS
T03373
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12
KO
K00458
arachidonate 12-lipoxygenase [EC:
1.13.11.31
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu00590
Arachidonic acid metabolism
ocu01100
Metabolic pathways
ocu01523
Antifolate resistance
ocu04726
Serotonergic synapse
ocu04750
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
100340525
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
100340525
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100340525
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100340525
Enzymes [BR:
ocu01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.31 arachidonate 12-lipoxygenase
100340525
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Motif
Other DBs
NCBI-GeneID:
100340525
NCBI-ProteinID:
XP_002718866
Ensembl:
ENSOCUG00000021659
UniProt:
G1U492
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Position
19:complement(9650435..9665954)
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AA seq
663 aa
AA seq
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MGRYHICVATGAWIFSGSHNRVQLWLVGARGEAELELQLRPARGEEEEFEHDVPEELGPL
QFVKLRKHHSLVDDAWFCDRITVRGPGAHETATFPCYRWVRGDGVLSLPEGSARLAVDNA
SDIFQKHRDKELEERQQMYRWATWKEGLLLTIAADSKDDLPPNMRFHEDKRLDFEWTLKT
VALEMIFKRVYTLLSSWDRLEDFDQIFWGQKSALAEKVRQHWQDDEFFGYQFLNGANPML
LRRSTCLPSRLMLPSGMEVLRVQLEKELQNGSLFEADFILLDGLPANVIRGEQQYLAAPL
VMLKMQPDGKLLPMVIQIQPPNAGSPTPTLFLPSDPPLAWLLAKSWVRNSDFQLHELQYH
LLNTHLVAEVIAVATMRCLPGLHPVFKLLMPHIRYTMEINTRARSQLISDGGIFDQAVST
GGGGHVQLLRRAVAQLTYHSLCPPHDLAERGLLGIPSALYAHDALRLWEIITRYVEGIVL
LFYQSDDVVRRDSELQAWCREITEVGLRQAQNRGFPISFQSQTQLCHFLTMCVFTCTVQH
GAINQGQLDWYGWVPNAPCTMRMPPPTTKDDVTMATVMGSLPDVRQSSLQMAITWHLGRQ
QPDMVPLGHHKEEYFSDPKAKAALSQFQTDLENFEKEITARNEPLDLPYEYLKPSRIENS
ITI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggccgctaccacatctgcgtagccaccggggcctggatcttctctgggtcgcacaac
cgcgtgcagctgtggctggtcggggcgcgcggggaggcggagctggagctgcagctgcgg
ccagcgcggggcgaggaggaggagttcgagcacgacgtccccgaggagctggggccgctg
cagttcgtgaagttgcgcaaacaccactcactggtggacgacgcgtggttctgcgaccgc
atcacggtgcggggccccggagcccacgagacagcgaccttcccgtgctaccgctgggtg
cgcggcgacggtgtcctgagcctgcctgagggcagcgcccgcctggcagtagacaatgcc
tcggacatcttccagaaacatcgagacaaggaactagaggaaagacagcagatgtaccgg
tgggccacctggaaggaaggcctgctcctgacaatagcagcagactctaaggacgatcta
ccccccaatatgagattccacgaggataagaggctggactttgaatggacgctaaagaca
gtggctctggagatgatcttcaaacgtgtttacactctcctgagctcctgggaccgtcta
gaagacttcgatcagatcttctggggccagaagagtgccctggctgagaaggttcggcag
cactggcaggacgatgagttttttggctaccagttcctcaatggcgccaaccccatgctg
ctgcgacgctccacctgcctgccctctaggctaatgctgccatcggggatggaggtgctt
cgcgtccaactggagaaagaactccagaacggctccctgtttgaggctgactttatcctg
ctggatggactcccagccaatgtgatccgaggagagcagcagtacctggctgcccccctc
gtcatgctgaagatgcaacccgatgggaagctgctccccatggtcatccagattcagcct
cccaacgccggctctcccaccccaacactgttcctgccctcagatcccccacttgcctgg
ctcctggccaagtcctgggtccgaaattcagatttccagctgcatgagctccagtatcac
ttgctgaacacgcatctggtggctgaggtcatcgctgtcgccaccatgaggtgcctcccg
ggactgcatcctgtcttcaagctcctcatgccccatatccgctacaccatggaaatcaac
acccgggcccggagccaactcatctccgatggaggaatatttgatcaggcagtgagcaca
ggtggagggggccatgtgcagctgctacgccgggcagtggctcagctgacctaccactcc
ctgtgccctcctcacgacctggctgagcggggcctgctgggaatcccaagtgccctctac
gcccacgatgctttgcggctctgggagatcatcaccaggtacgtggagggcatcgtcctc
ctcttctaccaaagcgatgacgttgtgaggcgtgactccgagctgcaggcctggtgtcgg
gagatcactgaggtggggctgcgccaggcccagaaccgaggtttccccatctccttccag
tcccagactcaactctgccacttcctgaccatgtgtgtcttcacgtgcacagtccagcat
ggggccatcaaccagggccagctggactggtatggctgggtcccgaatgccccatgcaca
atgcggatgcccccacctaccaccaaggacgatgtgacaatggctacggtcatggggtca
ctgcctgatgtccggcagtcctctcttcagatggccatcacgtggcatctgggtcgccag
cagccagacatggtgcctctggggcatcacaaagaagaatatttctcagatcccaaggcc
aaagctgcgctaagccaattccaaacagatctggaaaactttgaaaaagagatcacagcc
cggaacgagccccttgacctgccctatgaatacctgaagcccagccgcatagagaacagc
atcaccatctga
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