Oryctolagus cuniculus (rabbit): 100348477 Help Entry 100348477         CDS       T03373                                  Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu01524   Platinum drug resistance ocu04115   p53 signaling pathway ocu04210   Apoptosis ocu04215   Apoptosis - multiple species ocu04217   Necroptosis ocu04620   Toll-like receptor signaling pathway ocu04621   NOD-like receptor signaling pathway ocu04622   RIG-I-like receptor signaling pathway ocu04623   Cytosolic DNA-sensing pathway ocu04625   C-type lectin receptor signaling pathway ocu04657   IL-17 signaling pathway ocu04668   TNF signaling pathway ocu04932   Non-alcoholic fatty liver disease ocu04936   Alcoholic liver disease ocu05010   Alzheimer disease ocu05016   Huntington disease ocu05022   Pathways of neurodegeneration - multiple diseases ocu05132   Salmonella infection ocu05134   Legionellosis ocu05142   Chagas disease ocu05145   Toxoplasmosis ocu05152   Tuberculosis ocu05160   Hepatitis C ocu05161   Hepatitis B ocu05162   Measles ocu05163   Human cytomegalovirus infection ocu05164   Influenza A ocu05165   Human papillomavirus infection ocu05167   Kaposi sarcoma-associated herpesvirus infection ocu05168   Herpes simplex virus 1 infection ocu05169   Epstein-Barr virus infection ocu05170   Human immunodeficiency virus 1 infection ocu05200   Pathways in cancer ocu05203   Viral carcinogenesis ocu05416   Viral myocarditis ocu05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ocu00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     100348477  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     100348477    04215 Apoptosis - multiple species     100348477    04217 Necroptosis     100348477    04115 p53 signaling pathway     100348477  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     100348477    04621 NOD-like receptor signaling pathway     100348477    04622 RIG-I-like receptor signaling pathway     100348477    04623 Cytosolic DNA-sensing pathway     100348477    04625 C-type lectin receptor signaling pathway     100348477    04657 IL-17 signaling pathway     100348477  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100348477    05203 Viral carcinogenesis     100348477   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100348477    05161 Hepatitis B     100348477    05160 Hepatitis C     100348477    05164 Influenza A     100348477    05162 Measles     100348477    05168 Herpes simplex virus 1 infection     100348477    05163 Human cytomegalovirus infection     100348477    05167 Kaposi sarcoma-associated herpesvirus infection     100348477    05169 Epstein-Barr virus infection     100348477    05165 Human papillomavirus infection     100348477   09171 Infectious disease: bacterial    05132 Salmonella infection     100348477    05134 Legionellosis     100348477    05152 Tuberculosis     100348477   09174 Infectious disease: parasitic    05145 Toxoplasmosis     100348477    05142 Chagas disease     100348477   09164 Neurodegenerative disease    05010 Alzheimer disease     100348477    05016 Huntington disease     100348477    05022 Pathways of neurodegeneration - multiple diseases     100348477   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100348477    05416 Viral myocarditis     100348477   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100348477    04932 Non-alcoholic fatty liver disease     100348477   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100348477  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ocu01002]     100348477 Enzymes [BR:ocu01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      100348477 Peptidases and inhibitors [BR:ocu01002]  Cysteine peptidases   Family C14: caspase family    100348477 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  100348477 NCBI-ProteinID:  XP_051705254 LinkDB All DBs Position 7:complement(31541496..31602333) Genome browser AA seq 478 aa AA seqDB search MDLSSCLYKIGEQLDSEELASLKFLSLDYIPQRKQEPIQDALMLFQRLQEKRMLEENNLA FLKELLFRIHRLDLLSTLLGTSKEEMVTELQIPGRAHISAYRVMLFQISEDVSQLELKAF KFFLSREISKCKLEDNMSLLDIFIEMEKRALLGDRNLDTLKKICEQINKSLLVKIHDYED CSQGRRMSLGRTPGACSNGEEPYGVLALSDCPGEPASKAQTSEEVYQMKSKPRGYCLIVN NYDFSIARREMPRHRNMKDRKGTEVDAEALSNTFTDLHFEVVHYNDCTAKQICDILQSYQ SMDHKDRDCFVCCILSHGDKGIIYGTDGQEACIYDLTSYFTGSKCPSLAGKPKVFFIQAC QGDKYQQAVPVAIDSEQQETYLEMDSSFPKRYVPDEADFLLGMATVNNCVSYRNLFEGTW YIQSLCQSLRERCPQGEDILSILTKVNYKVSIKEAGEKKKQMPQPTFTLTKRLLFPLD NT seq 1437 nt NT seq  +upstreamnt  +downstreamnt atggatttatccagttgtctttacaaaattggggagcagctggacagcgaggagctggcc tccctgaagttcctgagcctggattacatcccacaaaggaagcaggagcccatccaggat gccttgatgctattccagagactccaggagaagcgcatgctggaggagaacaacctggcc ttcctgaaggagctgctcttccgaatccacagactggatctgctgagcactctgctgggc actagcaaggaggagatggtgacggagctgcagatcccaggcagggcccatatttctgcc tacagggtcatgctcttccagatttcagaagacgtaagccaactggaattgaaggctttt aaattttttttgagcagggagatctccaaatgtaaactggaagataacatgagcttgctg gacatcttcatcgagatggagaagagggccctccttggggatagaaacttggacaccctg aaaaagatctgtgagcaaatcaacaagagcctgctggtgaaaatccacgattatgaagac tgcagccaagggagaagaatgagcctgggaagaactcccggcgcatgttcaaacggggag gagccatatggagtgctggcactgtcagactgtccaggggagccagcgagcaaggcacag acatcagaagaagtttaccaaatgaaaagcaaacctcggggatactgtttgatcgtcaac aactacgattttagcatagcacggagagaaatgcccagacaccgcaacatgaaagacagg aaaggaacagaagttgatgcagaggctttgagcaataccttcactgaccttcactttgaa gtagtccattacaatgactgcacggcaaagcagatctgtgacattctgcaaagctaccaa agcatggaccacaaagacagagactgcttcgtctgctgcatcctgtcccatggagacaag ggcatcatctatggcactgatgggcaggaggcctgcatctatgatctgacctcttatttc actggttcgaagtgcccctctcttgctggaaaacccaaagtctttttcattcaagcttgt caaggggataagtaccagcaagccgttcctgttgcgatagactcagagcagcaagaaacc tatttagaaatggactcatcgtttccaaagagatacgtccccgatgaggctgacttcctg ctggggatggccactgtgaacaactgtgtctcctatcgaaacctctttgaggggacctgg tacatccagtcactttgccagagcctaagagaaagatgtcctcaaggcgaagatatcctc tccatcctgaccaaagtgaactataaagtgagcattaaggaagctggggaaaaaaagaag cagatgccacagcctactttcacactaacaaagagactcctcttccctctggattga

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