Oryctolagus cuniculus (rabbit): 100352056 Help Entry 100352056         CDS       T03373                                  Symbol PAK1 Name (RefSeq) p21 (RAC1) activated kinase 1   KO K04409   p21-activated kinase 1 [EC:2.7.11.1] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu04010   MAPK signaling pathway ocu04012   ErbB signaling pathway ocu04014   Ras signaling pathway ocu04024   cAMP signaling pathway ocu04062   Chemokine signaling pathway ocu04360   Axon guidance ocu04392   Hippo signaling pathway - multiple species ocu04510   Focal adhesion ocu04625   C-type lectin receptor signaling pathway ocu04650   Natural killer cell mediated cytotoxicity ocu04660   T cell receptor signaling pathway ocu04666   Fc gamma R-mediated phagocytosis ocu04810   Regulation of actin cytoskeleton ocu05132   Salmonella infection ocu05170   Human immunodeficiency virus 1 infection ocu05205   Proteoglycans in cancer ocu05211   Renal cell carcinoma Brite KEGG Orthology (KO) [BR:ocu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100352056 (PAK1)    04012 ErbB signaling pathway     100352056 (PAK1)    04014 Ras signaling pathway     100352056 (PAK1)    04392 Hippo signaling pathway - multiple species     100352056 (PAK1)    04024 cAMP signaling pathway     100352056 (PAK1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100352056 (PAK1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100352056 (PAK1)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     100352056 (PAK1)    04650 Natural killer cell mediated cytotoxicity     100352056 (PAK1)    04660 T cell receptor signaling pathway     100352056 (PAK1)    04666 Fc gamma R-mediated phagocytosis     100352056 (PAK1)    04062 Chemokine signaling pathway     100352056 (PAK1)   09158 Development and regeneration    04360 Axon guidance     100352056 (PAK1)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     100352056 (PAK1)   09162 Cancer: specific types    05211 Renal cell carcinoma     100352056 (PAK1)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100352056 (PAK1)   09171 Infectious disease: bacterial    05132 Salmonella infection     100352056 (PAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ocu01001]     100352056 (PAK1)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ocu04131]     100352056 (PAK1)    03036 Chromosome and associated proteins [BR:ocu03036]     100352056 (PAK1) Enzymes [BR:ocu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      100352056 (PAK1) Protein kinases [BR:ocu01001]  Serine/threonine kinases: STE group   STE20 family    100352056 (PAK1) Membrane trafficking [BR:ocu04131]  Exocytosis   Calcium ion-dependent exocytosis    Kinases and associated proteins     100352056 (PAK1)  Endocytosis   Macropinocytosis    Kinases     100352056 (PAK1) Chromosome and associated proteins [BR:ocu03036]  Eukaryotic type   Sister chromatid separation proteins    Aurora kinases     Regulators of Aurora kinases      100352056 (PAK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal DSHCT APH Kdo Motif Other DBs NCBI-GeneID:  100352056 NCBI-ProteinID:  XP_017199968 Ensembl:  ENSOCUG00000010538 UniProt:  G1TLL9 LinkDB All DBs Position 1:139220747..139414205 Genome browser AA seq 544 aa AA seqDB search MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILP GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN PQAVLDVLEFYNSKKTSNSQKYMSFTDKSTEDYNSSNTLNVKTVSETPAVPPVSEDEDDE DDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEK QKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQM NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCM DEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKR STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGT PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT KNNH NT seq 1635 nt NT seq  +upstreamnt  +downstreamnt atgtcaaataacggcctagacattcaagacaaacccccggcccctccgatgagaaacacc agcactatgattggagcaggcagcaaagatgctggaaccctgaaccatggttccaaacct ctacccccaaacccagaggagaagaagaagaaggaccgcttttaccgatccatcttacct ggagataaaacaaataaaaagaaggaaaaggagcggccagaaatttctcttccttcagat tttgagcacacaattcacgttggttttgatgctgtcacaggggagtttacgggaatgcca gagcagtgggcccgcttgcttcagacatcaaatattactaagtcggaacagaagaaaaac ccgcaggctgttctggatgtgttagaattttacaactcaaagaagacctccaacagccag aagtacatgagctttacagataaatctactgaggattataattcttctaacactttgaat gtgaagactgtgtctgagactcctgcagtgccaccagtttcagaagatgaagatgatgaa gatgatgctactccacctccagtgattgctccacgtccagagcacacaaaatctgtatac acacgttctgtgattgaaccactgcctgttaccccaactcgggatgtggctacatctccc atttcacctactgagaataataccactccaccggatgctttgacccggaatactgaaaag cagaagaagaagcctaaaatgtctgatgaggagatcttggagaaattacgaagcatagtg agtgtgggcgatcctaagaagaaatatactcggtttgagaagattggacaaggtgcttca ggcaccgtatacactgcaatggatgtagccacaggacaggaggtggccattaagcagatg aacctgcagcagcagccaaagaaagagctgattattaatgagatcctggtcatgagggaa aacaagaacccaaatattgtgaactacttggacagttatcttgtgggggatgagctgtgg gtcgtcatggaatacttggctggaggctccttgacagatgtggtgacagaaacctgtatg gatgaaggccagattgcagctgtgtgccgtgagtgtttgcaggctctggagtttctgcat tcgaaccaggtcatacacagagacatcaagagtgacaatattctattgggaatggatggc tctgtcaagctaactgattttggattctgtgcacaaataactccagagcagagcaaacgg agcaccatggtgggaaccccatactggatggcaccggaggttgtgacacggaaggcctat gggcccaaggttgacatctggtccctgggcatcatggcgattgaaatgattgaaggggag cctccatacctcaatgaaaaccctctaagagccttgtacctcattgccaccaatggaacc ccagagcttcagaacccagagaagctgtcggctattttccgggactttctgaaccgctgt ctcgagatggatgtggagaagagaggttcagcaaaagagctgctacagcatcaattcctg aagattgccaagcccctctccagcctcactccactgatcgctgcagcaaaggaggcaacc aagaacaatcactaa

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