Oryctolagus cuniculus (rabbit): 100356696
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Entry
100356696 CDS
T03373
Symbol
ITCH
Name
(RefSeq) itchy E3 ubiquitin protein ligase
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu04120
Ubiquitin mediated proteolysis
ocu04144
Endocytosis
ocu04668
TNF signaling pathway
ocu04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100356696 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
100356696 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100356696 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100356696 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ocu04131
]
100356696 (ITCH)
04121 Ubiquitin system [BR:
ocu04121
]
100356696 (ITCH)
Enzymes [BR:
ocu01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
100356696 (ITCH)
Membrane trafficking [BR:
ocu04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
100356696 (ITCH)
Ubiquitin system [BR:
ocu04121
]
Ubiquitin ligases (E3)
HECT type E3
100356696 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
100356696
NCBI-ProteinID:
XP_008254311
Ensembl:
ENSOCUG00000015354
UniProt:
G1T9A1
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All DBs
Position
4:complement(5212181..5339477)
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AA seq
864 aa
AA seq
DB search
MSDSGSQFGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLDSEIVTNGETTCSESASQNDDGSRPKDETRVNTNGS
DDPEDTGSSENRRVSGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPPATSESD
GSSTSSLPPTNTNINTSTSEGATSGLIIPLTISGGSGPRPLNTVTQAPLPPGWEQRVDQH
GRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQ
WQLQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNH
NTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNG
PQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWV
IFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFR
FIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEEC
GLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFE
GFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEI
DNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPP
YKSYEQLKEKLLFAIEETEGFGQE
NT seq
2595 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacaatttggttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatctcagccaaacttaaggaaaataaaaagaattggtttggaccaagt
ccttatgtagaagtcacagttgatgggcagtcaaagaagacagaaaaatgcaataataca
aacagtcccaaatggaagcaaccccttacagttattgttacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacattgaaatctgatgttttattgggaactgctgcatta
gatatttatgaaaccttaaagtcaaacaatatgaaacttgaggaggtggttgtgactttg
cagcttgtaggtgacaaagagccaacagagacaatcggagacttatcagtttgtctggat
gggctgcaattagattctgagattgttactaatggtgaaactacatgttcagaaagtgct
tcacagaatgatgatggctccagacccaaggatgaaacaagagtgaatacaaatggatca
gatgaccctgaggatacagggtccagtgaaaataggagggtcagtgggaataattctcca
tcactctcaaatggcggttttaagccttctaggccaccaagaccttcccgaccacctcca
cccaccccacgtagaccagcatctgtcaatggttctccacctgctacttctgaaagtgat
ggatcaagtacaagctctctgccacccacaaatacaaatataaatacaagtacatctgaa
ggagcaacatctggattaataattcctcttaccatatctggaggctcaggccctaggcca
ttaaatactgtaactcaagctcccctaccacctgggtgggagcagagagtagaccaacat
gggcgagtttactatgtagatcatgtcgaaaaaagaacaacgtgggatagaccagaacct
ctacctcctggctgggaacggcgggttgacaacatgggacgtatttattacgttgaccat
ttcacaagaacaacaacatggcagaggccaacattggaatctgtccggaactatgaacag
tggcagctacaacgtagtcaacttcaaggagcaatgcagcagtttaaccagagattcatc
tatgggaatcaagatttgtttgccacatcacaaaataaagaatttgatccccttggtcct
ttgccacctggttgggagaagagaactgacagcaatggcagagtgtattttgtcaaccat
aacactcgaattacacaatgggaagacccccgaagtcaaggtcaattaaatgaaaagccc
ttacctgaaggttgggaaatgagattcacagtggatggaattccatattttgtggaccat
aatagaagaacaactacctatatagatcctcgcacaggaaaatctgccctagacaatggg
ccacagatagcctatgttcgggacttcaaagcaaaggttcagtatttccggttctggtgt
cagcaactggccatgccacagcacataaagattacagtgaccagaaaaacgttgtttgag
gattcctttcaacagataatgagcttcagtccccaagatctgcgaagacgtttgtgggtg
atttttccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttctt
ttgtcacatgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataac
tactgcttgcagataaaccctgcttcttacatcaatccagatcacctgaaatattttcgc
tttattgggaggtttattgccatggctctatttcatgggaaattcatagacacaggcttc
tctttaccattttataaacgtatcttgaacaaaccagttggacttaaggatttagaatct
attgatccagaattttataattccctcatctgggttaaagaaaacaatattgaggaatgt
ggtttggaaatgtacttttccgttgataaagaaattctaggtgaaattaagagtcatgat
ctgaaaccaaatggtggcaatattcttgtaacagaagaaaataaagaggaatatatcaga
atggtagctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgag
ggctttaatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaattagag
gttcttttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatttac
cgtcattacactcggacaagcaaacagatcatgtggttctggcagtttgttaaagaaata
gataatgagaagagaatgcgacttctgcagtttgttactggaacctgccgattgccagta
ggaggatttgctgacctcatggggagcaatggaccacagaaattctgcattgaaaaagtt
ggaaaggagaattggttacccagaagtcatacttgttttaaccgcctggacctgccaccc
tacaagagctatgagcaactgaaggaaaagctgttgtttgccattgaagaaacagaagga
ttcgggcaagagtaa
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