KEGG   Oryctolagus cuniculus (rabbit): 100359209
Entry
100359209         CDS       T03373                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
ocu  Oryctolagus cuniculus (rabbit)
Pathway
ocu00670  One carbon pool by folate
ocu00790  Folate biosynthesis
ocu01100  Metabolic pathways
ocu01240  Biosynthesis of cofactors
ocu01523  Antifolate resistance
ocu04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:ocu00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100359209 (DHFR)
   00670 One carbon pool by folate
    100359209 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    100359209 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100359209 (DHFR)
Enzymes [BR:ocu01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     100359209 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 100359209
NCBI-ProteinID: XP_051710035
Ensembl: ENSOCUG00000005127
LinkDB
Position
11:88276169..88290329
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINIVLSRELKEPPQGAHFLAKSLADALKLIEEPELADKVDMVWIVGGSS
VYKEAMNQPGHLRLFVTRIMQEFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKF
EVYEKND
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtccgctcaactgcatcgtcgctgtgtcgcagaacatgggcatcggcaagaac
ggggacctgccgtggcccccgctcaggaacgaattcaggtatttccagagaatgaccaca
acgtcgtcagtggaaggtaaacagaacctggtgattatggggaggaagacctggttctcc
attccagagaagaatcggcctttaaaggacagaatcaacatagttctcagtagagaactc
aaggaaccgccacaaggagcacatttcctcgctaagagtctggctgatgccttaaaactt
attgaggaaccagaattggcagataaagtggacatggtctggatagtgggaggcagctct
gtgtataaggaagccatgaatcagccaggccatctcagactgtttgtgacaaggatcatg
caggaatttgaaagtgacacgttttttccagaaatcgatttggagaaatacaaactgctc
ccagagtacccaggcgtcctttctgatgtccaggaggagaaaggcatcaagtacaaattt
gaagtttatgaaaagaacgattaa

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