Oryctolagus cuniculus (rabbit): 103347035 Help Entry 103347035         CDS       T03373                                  Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism ocu  Oryctolagus cuniculus (rabbit) Pathway ocu00230   Purine metabolism ocu01100   Metabolic pathways ocu01522   Endocrine resistance ocu04015   Rap1 signaling pathway ocu04020   Calcium signaling pathway ocu04022   cGMP-PKG signaling pathway ocu04024   cAMP signaling pathway ocu04062   Chemokine signaling pathway ocu04072   Phospholipase D signaling pathway ocu04114   Oocyte meiosis ocu04211   Longevity regulating pathway ocu04213   Longevity regulating pathway - multiple species ocu04261   Adrenergic signaling in cardiomyocytes ocu04270   Vascular smooth muscle contraction ocu04371   Apelin signaling pathway ocu04540   Gap junction ocu04611   Platelet activation ocu04713   Circadian entrainment ocu04714   Thermogenesis ocu04720   Long-term potentiation ocu04723   Retrograde endocannabinoid signaling ocu04724   Glutamatergic synapse ocu04725   Cholinergic synapse ocu04727   GABAergic synapse ocu04750   Inflammatory mediator regulation of TRP channels ocu04911   Insulin secretion ocu04912   GnRH signaling pathway ocu04913   Ovarian steroidogenesis ocu04914   Progesterone-mediated oocyte maturation ocu04915   Estrogen signaling pathway ocu04916   Melanogenesis ocu04918   Thyroid hormone synthesis ocu04921   Oxytocin signaling pathway ocu04923   Regulation of lipolysis in adipocytes ocu04925   Aldosterone synthesis and secretion ocu04926   Relaxin signaling pathway ocu04927   Cortisol synthesis and secretion ocu04928   Parathyroid hormone synthesis, secretion and action ocu04934   Cushing syndrome ocu04935   Growth hormone synthesis, secretion and action ocu04970   Salivary secretion ocu04971   Gastric acid secretion ocu04972   Pancreatic secretion ocu04976   Bile secretion ocu05032   Morphine addiction ocu05142   Chagas disease ocu05146   Amoebiasis ocu05163   Human cytomegalovirus infection ocu05166   Human T-cell leukemia virus 1 infection ocu05200   Pathways in cancer ocu05207   Chemical carcinogenesis - receptor activation ocu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ocu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     103347035  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     103347035    04371 Apelin signaling pathway     103347035    04020 Calcium signaling pathway     103347035    04072 Phospholipase D signaling pathway     103347035    04024 cAMP signaling pathway     103347035    04022 cGMP-PKG signaling pathway     103347035  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103347035   09144 Cellular community - eukaryotes    04540 Gap junction     103347035  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     103347035    04062 Chemokine signaling pathway     103347035   09152 Endocrine system    04911 Insulin secretion     103347035    04923 Regulation of lipolysis in adipocytes     103347035    04912 GnRH signaling pathway     103347035    04913 Ovarian steroidogenesis     103347035    04915 Estrogen signaling pathway     103347035    04914 Progesterone-mediated oocyte maturation     103347035    04921 Oxytocin signaling pathway     103347035    04926 Relaxin signaling pathway     103347035    04935 Growth hormone synthesis, secretion and action     103347035    04918 Thyroid hormone synthesis     103347035    04928 Parathyroid hormone synthesis, secretion and action     103347035    04916 Melanogenesis     103347035    04925 Aldosterone synthesis and secretion     103347035    04927 Cortisol synthesis and secretion     103347035   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     103347035    04270 Vascular smooth muscle contraction     103347035   09154 Digestive system    04970 Salivary secretion     103347035    04971 Gastric acid secretion     103347035    04972 Pancreatic secretion     103347035    04976 Bile secretion     103347035   09156 Nervous system    04724 Glutamatergic synapse     103347035    04727 GABAergic synapse     103347035    04725 Cholinergic synapse     103347035    04720 Long-term potentiation     103347035    04723 Retrograde endocannabinoid signaling     103347035   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     103347035   09149 Aging    04211 Longevity regulating pathway     103347035    04213 Longevity regulating pathway - multiple species     103347035   09159 Environmental adaptation    04713 Circadian entrainment     103347035    04714 Thermogenesis     103347035  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103347035    05207 Chemical carcinogenesis - receptor activation     103347035   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     103347035    05163 Human cytomegalovirus infection     103347035   09174 Infectious disease: parasitic    05146 Amoebiasis     103347035    05142 Chagas disease     103347035   09165 Substance dependence    05032 Morphine addiction     103347035   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     103347035   09167 Endocrine and metabolic disease    04934 Cushing syndrome     103347035   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     103347035 Enzymes [BR:ocu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      103347035 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom Motif Other DBs NCBI-GeneID:  103347035 NCBI-ProteinID:  XP_051684362 LinkDB All DBs Position Unknown AA seq 1108 aa AA seqDB search MYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK PPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR RIKILGDCYYCVSGLTQPKADHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKATLACLNGDYEVEPGHGQERNSF LRAHDIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRRMFKAEIPFS NVMSCEDDDKRRALRTASEKVRNRSSFSTNVVYATPGSRVNRYISRLLEARQTELEMADL NFFTLKYKHVERERKYHQLQDECFTTAVVLALVLAALFGLVYLLIIPQSVAVLLLLVFCI CFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWPAKANS SMVVLAAGGRRTVLPAMPCESAPHALLCCLVGTLPLAVFLRVSSLPKMVLLCGLTASYIL ALELGGYGEAGAGAAPGRSYEPVMAILLFSCTLALHARQVDIKLRLDYLWAAQAEEERDD MERVKVDNKRILFNLLPAHVAQHFLMSNPRNMRQPVPSPGATCCARSLKLWELVSRGCAR AARLSELPWNAPEPQTPGEVWVGFRVLEAAREPSPSLTLPLGCAEPSPVGSDYAYVAELG DEDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKDFYKD LEKIKTIGSTYMAAVGLAPTAGTRYWVIAEFWIIAEYWIIAKYWIKAEYRIIAEYWIIAE YWIIAECQIIAEYWIIAECRIIAEYRIIAEYWIIAEYRIIAKKSISCHLSALADFAIEMF DVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQ VTEDVHRLLRKCPYHFVCRGKVSVKGKGEMLTYFLEGRTDGSGSQPRSLSLGQKMCPYGR GGLQARRPPLGPAAGPLWPCRGQARLAPASALWEIRRTRGEGAEVWLAVTKETQHSSVSI RPERILTPAMSGGLESQKGRLRLHDGPW NT seq 3327 nt NT seq  +upstreamnt  +downstreamnt atgtacggcgtgttcgtgcgcatcctgaccgagcgctcacagcgcaaggccttcctgcag gcacggagctgcattgaggaccggctgcggctggaagacgagaatgagaagcaggagcgg ctcctcatgagcctcctgccccgcaacgtcgccatggagatgaaggaggacttcctgaag ccgccagagaggatcttccacaagatctacatccagagacacgacaacgtgagcatcctg tttgcggacatcgtgggcttcacggggctggcgtcccagtgcacggcccaggagctggtc aaactcctcaacgagctgttcggcaagtttgatgaattagccacggagaaccactgtcgc cgcatcaagatcctgggggactgctactactgcgtgtccggcctcacccagcccaaggcc gaccacgcccactgctgcgtggagatgggactggacatgatcgacaccatcacgtccgtg gccgaggccaccgaggtggacctgaacatgcgcgtggggctgcacacgggccgtgtgctc tgcggcgtgctgggcctgcgcaagtggcagtatgacgtgtggtccaacgacgtgaccctg gccaacgtcatggaggccgctggcctgcccgggaaggttcacatcacaaaggcaaccctg gcctgcttgaacggggactacgaggtggagccgggtcacgggcaggagaggaacagcttc ctgagggcccacgacatcgagacgttctttatcgtgccgtcgcatcgcaggaagatcttc ccaggcctgattctctcagacatcaaaccggccaagcggatgaagttcaagaccgtgtgc tacctgctggtgcagctcatgcactgccggcggatgttcaaggccgagatccccttctcc aacgtcatgagctgtgaggatgacgacaagaggagggcgctgaggacagcctcggagaaa gtccgaaaccgctcgtccttctcgacaaacgtcgtctacgccacgccgggctcgcgcgtc aacaggtacatcagccgcctcctggaagcccgccagacggaactggagatggcggatctc aacttcttcacgctgaagtacaagcacgtggagcgggagcggaagtaccatcagctgcag gacgagtgttttaccactgccgttgtcctcgccctcgtcctggctgccttgttcggcctc gtctaccttctgatcatcccgcagagtgtggccgtcctgctcctgctggtcttctgcatc tgcttcctggtggcctgtgtcctgtacctgcacatcacccgagtccagtgttttccaggg tgcctcaccatccagatccgcaccgtcctgtgcattttcatcgtggtcttgatctactcg gtagcccagggctgcgtggtgggctgcctgccctgggcctggcccgccaaggccaacagc tccatggtggtcctggcagccggcggccggcgcaccgtgctgcctgccatgccctgtgag tctgcgccgcacgccctgctctgctgcctggtgggcaccctgccgctggccgtgttcctg cgcgtgtcctccctgcccaagatggtcctgctgtgcgggctcactgcctcctacatcctg gccctggagctcggcggctacggcgaggccggggccggagccgccccggggcgcagctac gagccggtcatggccatcctgctcttctcctgcacgctggccctgcacgccaggcaggtg gacatcaagctgcggctggactacctctgggcagcgcaggcggaagaggagcgagacgac atggagcgggtgaaggtggacaacaagcggatcctgttcaacctgctgcccgcccacgtg gcccagcacttcctcatgtccaacccacgcaacatgcggcagcctgtgcccagccccggg gcgacgtgctgcgcgcgctccctgaagctctgggagctcgtgtcccgtggctgcgctcgt gcggcaaggctctcagaactgccgtggaacgcgccagagccccagactccaggcgaggtg tgggttgggttccgggtcctggaggcagcccgggagcccagcccgagtctcaccctcccg ctcggctgtgcagagccctcccctgtgggctctgattacgcttacgtggctgagctcggg gacgaggacctctactaccagtcctactcccaggtgggcgtcatgttcgcctccatcccc aacttcaacgacttctacatcgagctggacggcaacaacatgggggtggagtgcctgcgg ctcctcaacgagatcatcgccgacttcgacgagctcatggacaaagacttttacaaggac ctagagaagatcaagaccatcgggagcacctacatggctgcagtggggctggcgcccacg gccggcaccaggtactgggttatagctgagttctggattatagccgagtactggattata gccaagtactggattaaagccgagtaccggattatagccgagtactggattatagccgag tactggattatagccgagtgccagattatagccgagtactggattatagccgagtgccgg attatagctgagtaccggattatagccgagtactggattatagctgagtaccggattata gctaaaaagtccatctcctgccacctcagcgccctggccgactttgccatcgagatgttc gacgtcctggatgagatcaactaccagtcctacaacgacttcgtcctccgcgtgggcatc aatgtgggccccgtggtggccggggtgattggcgctcgccggccgcagtatgacatctgg gggaacacggtcaatgtggccagtcggatggacagcactggcgtccagggccgaatccag gtgacggaggacgtccaccggctgctgagaaagtgcccctaccacttcgtgtgccgaggc aaagtcagcgtgaagggcaagggggagatgctgacctacttcctggaaggcaggaccgac gggagcggctcccagcccaggtccctgagcctggggcagaagatgtgtccttacgggaga ggtggcctccaggccaggcgccccccactgggccctgcggccggccccctgtggccctgc cggggtcaggccaggctggcgccagcgtcagcactttgggagatccgtcggactcggggc gagggcgcggaagtctggctggcggtgaccaaggagacccaacacagctccgtgtccatc cggcccgagcggatcctgactccagccatgagcggcggccttgagagccagaagggaagg ctgcgtctccacgacggcccctggtga

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