Oryctolagus cuniculus (rabbit): 127491144
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Entry
127491144 CDS
T03373
Name
(RefSeq) receptor tyrosine-protein kinase erbB-3-like isoform X1
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
ocu
Oryctolagus cuniculus (rabbit)
Pathway
ocu01521
EGFR tyrosine kinase inhibitor resistance
ocu04010
MAPK signaling pathway
ocu04012
ErbB signaling pathway
ocu04020
Calcium signaling pathway
ocu04151
PI3K-Akt signaling pathway
ocu05205
Proteoglycans in cancer
ocu05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ocu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
127491144
04012 ErbB signaling pathway
127491144
04020 Calcium signaling pathway
127491144
04151 PI3K-Akt signaling pathway
127491144
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
127491144
05205 Proteoglycans in cancer
127491144
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
127491144
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ocu01001
]
127491144
Enzymes [BR:
ocu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
127491144
Protein kinases [BR:
ocu01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
127491144
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
GF_recep_IV
Recep_L_domain
Furin-like
Pkinase
Kinase-like
TM_ErbB1
Motif
Other DBs
NCBI-GeneID:
127491144
NCBI-ProteinID:
XP_051702275
LinkDB
All DBs
Position
4:47204448..47228527
Genome browser
AA seq
1297 aa
AA seq
DB search
MLASEAATKPPVPQGQPWDWDFLVLPSLSLTRSPSQWIREVTGYVLVAMNEFSTLPLPNL
RVVRGTQVYDGKFAIFVMLNYNTNSSHALRQLRFTQLTEILSGGVYIEKNDKLCHMDTID
WRDIVRDPGAEIVVKDNGRSCPPCHEVCKGRCWGPGPEDCQTLTKTICAPQCNGHCFGPD
PNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPLVYNKLTFQLEPNPHTKYQY
GGVCVVSCPHNFVVDQTSCVRACPPDKMEVDKNGLKICEPCGGLCPKACEGTGAGSRFQT
VDSSNIDGFVNCTKILGNLDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSW
PPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGLRSLKEISAGRIYISANRQL
CYHHSLNWTRLLRGPAEERLDIKHNRPRRECVAEGKVCDPLCSPGGCWGPGPGQCLSCRN
YSRGGVCVTHCNFLNGEPREFAHEDECFSCHPECQPMEGTATCNGSGSDACAQCAHFRDG
PHCVSSCPNGVLGAKGPIYKYPDVHNECRPCHENCTQGCKGPELQDCLGQTLVLISKTHL
AMAVTVGLAVIFLILGGTFLYWRGRRIQNKRAMRRYLERGESLEPLDPSEKANKVLARIF
KETELRKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIG
SLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVRQQRESLGPQLLLNWGVQIAKGMYY
LEEHGMVHRNLAARNVLLKSASQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIH
FGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVM
VKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRESGPGVPPGAEPSALTNKELEEVE
LEPELDLDLDLEAEEDTLATTLGSALSLPVGTLTRPRGSQSLLSPSSGYMPMNQSVLGEA
CQESAVCGGSERCPRPVSLHPVPRGRLTSESSEGHVTGSEAELPEKVSVCRSRSRSRSPR
PRGDSAYHSQRHSLLTPVTPLAPPGLEEEDVNGYVMPDTHLKGTPSSREGTLSSVGLSSV
LGTEEEDEDEEYEYMNRRRRPSPSHPPRPGSLEELGYEYMDVGSDLSASLGSTQSCPLNP
VPVISTAGTTPDEDYEYMNRRRGAGGPGGDYTAMGACPAAEQGYEEMRAFQGPGPHAPSV
RYARLKTLRSLEATDSAFDNPDYWHSRLFPKANAQRT
NT seq
3894 nt
NT seq
+upstream
nt +downstream
nt
atgctggcatcagaggcagccactaaaccccctgtgccccaaggtcagccctgggattgg
gattttttggttctgccatccctctcattgacgcgctctccatcacagtggatccgagaa
gtgacgggctacgtcctcgtggccatgaacgagttctctacgctacccttgcccaacctc
cgagtggtgcgcgggactcaggtgtacgatgggaagttcgccatctttgtcatgttgaac
tacaataccaactccagccacgcgctgcgccagctccgcttcactcagctcaccgagatt
ctgtccgggggcgtttatatcgagaagaatgacaagctttgtcacatggacacgatcgac
tggagggacatcgtgagggacccaggagctgagatagtggtgaaggacaatggccggagc
tgtcccccgtgtcacgaggtctgcaaggggagatgctggggtcctggaccagaagactgc
cagacactgaccaagaccatctgtgcccctcagtgtaacggccactgctttgggcccgac
cccaaccagtgctgccatgatgagtgcgccgggggctgctcaggccctcaggacaccgac
tgcttcgcctgccgacacttcaatgacagcggagcctgcgtaccccggtgtccacaacct
ctcgtctacaacaagctgactttccagctagaacccaacccccataccaagtaccagtac
ggaggggtttgtgtggtcagctgtcctcataactttgtggtggatcaaacttcctgcgtc
agggcctgtcctcctgacaagatggaagtggacaaaaatgggctgaagatatgcgagcct
tgtggggggctgtgccccaaagcctgcgaggggacgggcgctgggagtcgcttccagact
gtggactcgagcaacatcgatggatttgtgaactgcaccaagatcctgggcaacctggac
tttcttatcaccggcctcaacggagacccctggcacaagatccctgccctggaccctgag
aagctcaacgtcttccgcacagtccgggagatcacaggctacctgaatatacaatcctgg
cctccccacatgcacaacttcagcgttttttccaacctcacgaccatcgggggcagaagc
ctctacaaccggggcttctctttgttgatcatgaagaacttgaacgtgacgtctctgggc
ctccgatccctgaaagagattagtgctgggcgtatctatataagtgccaaccggcagctg
tgctaccaccattctctgaactggacccggctgctccgggggcctgcggaagagagactg
gacatcaagcataatcggccgcgcagggagtgtgtggcggagggcaaagtgtgtgacccg
ctgtgctcccccgggggatgctggggcccaggcccgggtcagtgcctctcctgtcggaac
tacagccgcggaggtgtctgtgtgacccactgcaactttctgaacggggagcctcgagag
tttgctcatgaggacgaatgtttctcctgccacccggaatgccagcccatggaaggcact
gccacgtgcaatggctcgggctccgatgcttgtgcccagtgtgcccattttcgagatggg
ccccactgtgtgagcagctgccccaatggagttctaggtgccaagggcccgatctacaag
tacccggatgttcacaatgaatgtcggccgtgccacgagaactgcacccaggggtgtaag
ggaccagaactacaagactgtttaggccaaacactggtgctgatcagcaaaacccatctg
gcaatggctgtgacagtaggattggcagtgatcttcctgattctggggggcacatttctc
tactggcgtgggcgccggattcagaataaaagggctatgaggcgctacctggaacgtggt
gagagcttagagcctctggatcccagcgagaaggctaacaaagtcttggccagaatcttc
aaagagacagagctgaggaagcttaaagtgcttggttccggcgtctttggaactgtgcac
aaaggtgtgtggatccccgagggtgaatccatcaagattccagtgtgcattaaagtcatc
gaagacaagagtggacggcaaagttttcaggccgtgacggatcacatgctggccatcggc
agcctggaccacgcccacatcgtacggctgctgggactgtgcccagggtcatcgctgcag
ctcgtcactcaatacctgcctctgggttccctgctggatcatgtgaggcagcagcgggag
tcgctggggccacagctgctgctcaactggggcgtacaaatcgctaagggcatgtactat
cttgaggagcacggtatggtgcacaggaacctggctgcccgcaacgtgctgctgaagtca
gccagtcaggttcaggtggcagattttggtgtggctgacctgctgcccccagatgataag
cagctcctccacagtgaagccaagactccaattaagtggatggctcttgagagtatccac
tttgggaaatacacacaccagagtgacgtctggagctacggtgtgacagtttgggagctg
atgaccttcggtgcagagccctatgcagggctgcgattagcagaagtaccagacctgttg
gagaagggggaacggttggcacagccccagatctgcaccattgatgtctacatggtcatg
gtcaagtgttggatgattgatgagaacattcgcccaacctttaaagaactagccaatgag
ttcaccaggatggcccgagatccaccacggtatctagtcataaagagggagagtgggcct
ggagtacctcctggggcagagccctctgctctgacaaacaaggaactggaggaagtagag
ctggagccagaacttgacctagacctagacttggaggcagaagaggacaccctggcaacc
acactgggctctgctctcagcctaccagttggaactcttactcgaccacgggggagccag
agcctgttaagtccatcatctggatacatgcccatgaaccagagtgttcttggagaggcc
tgccaggagtctgcagtttgtgggggcagtgaacgatgccctcgtccggtctctctgcac
ccagtgccacggggccgcctgacctccgaatcgtcagaaggtcacgtgacaggctctgag
gctgagctcccggagaaggtgtcggtgtgcaggagccgcagccgcagccgcagcccacgg
ccaaggggagatagtgcctaccattcccagcgccatagcctgcttacgcccgtcacccct
cttgccccgccaggattggaagaagaggatgtcaacggttatgtcatgccagatacacac
ctcaaaggtactccttcttcccgagaaggtactctttcctcagtgggtctcagctctgtc
ctgggtactgaagaggaagatgaagatgaggagtatgaatacatgaaccgtcggagaagg
cccagcccatctcatccccctcggcccggctcccttgaggagctgggctatgagtacatg
gacgtggggtcagacctcagtgcctccctgggcagcacgcagagttgtcctctcaaccct
gtgcccgtcatatccactgctggcacgacaccagatgaggactatgagtatatgaatcgg
cgacgcggtgcaggtggcccgggaggggattacacagccatgggggcctgcccagcagct
gagcaagggtatgaagagatgcgagctttccaggggcctggtccgcatgcccctagtgtc
cgctacgcccgcctcaaaaccctccgcagtttagaagccaccgactccgcctttgacaac
cctgattactggcatagcaggcttttccccaaggctaacgcccagagaacatag
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