Ochotona curzoniae (black-lipped pika): 121146116
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Entry
121146116 CDS
T11174
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz01524
Platinum drug resistance
ocz04010
MAPK signaling pathway
ocz04071
Sphingolipid signaling pathway
ocz04141
Protein processing in endoplasmic reticulum
ocz04210
Apoptosis
ocz04530
Tight junction
ocz04668
TNF signaling pathway
ocz04714
Thermogenesis
ocz04722
Neurotrophin signaling pathway
ocz04932
Non-alcoholic fatty liver disease
ocz04936
Alcoholic liver disease
ocz05010
Alzheimer disease
ocz05012
Parkinson disease
ocz05014
Amyotrophic lateral sclerosis
ocz05016
Huntington disease
ocz05017
Spinocerebellar ataxia
ocz05022
Pathways of neurodegeneration - multiple diseases
ocz05208
Chemical carcinogenesis - reactive oxygen species
ocz05417
Lipid and atherosclerosis
ocz05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
121146116 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
121146116 (MAP3K5)
04668 TNF signaling pathway
121146116 (MAP3K5)
04071 Sphingolipid signaling pathway
121146116 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
121146116 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
121146116 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
121146116 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
121146116 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
121146116 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
121146116 (MAP3K5)
05012 Parkinson disease
121146116 (MAP3K5)
05014 Amyotrophic lateral sclerosis
121146116 (MAP3K5)
05016 Huntington disease
121146116 (MAP3K5)
05017 Spinocerebellar ataxia
121146116 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
121146116 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
121146116 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
121146116 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
121146116 (MAP3K5)
04932 Non-alcoholic fatty liver disease
121146116 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
121146116 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ocz01001
]
121146116 (MAP3K5)
Enzymes [BR:
ocz01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
121146116 (MAP3K5)
Protein kinases [BR:
ocz01001
]
Serine/threonine kinases: STE group
STE11 family
121146116 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
121146116
NCBI-ProteinID:
XP_040821347
LinkDB
All DBs
Position
Unknown
AA seq
1375 aa
AA seq
DB search
MSADAGEGITFSVPTFAPSGLCPWPEGGSCRRGATAVAEGEEKQLPAPPPAGSFWNVEST
GVPGTAGPAAGAPGSGAPRCRGSSGSGPGRRTTVAYVINEASQGQLVVAESEALQSLREA
CEAVGATLETLHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMAN
NIILYCDTNADSLQSLKDIICQKNTMCTGNYTFVPYMVTPHNKVYCCDSSLMKGLTELMQ
PNLELFLGPICLPLVDRFIRLLKMAQASSSQYFRESILSDIRKARNLYTGKELAAELARI
RQRIDNIEILTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFAL
NRRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDRGASWF
KKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGSLENLQSYWEVG
FFLGASVLANDHVRVIQASEKLFKLKTPAWYLKSMVETILIYKHFVKLTTEQPVAKQELV
DFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGI
HEWNFSAASVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGR
GTEEGDCEGDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYS
QPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQT
IGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETF
TGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFHELGEPQAAMFKVGMFKV
HPEIPESMSAEAKAFILKCFEPDPDKRACANDLLIDEFLKVSSKKKKTQPKLSALSAGSN
EYLRSISLPVPVLVEDTSSSSEYGSVSPDTELKADPFSFKTRAKSCGEKDGKGIRTLFLG
IPDENFEDHSAPPSPEEKDSGFFLLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEE
PKLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVN
KVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADPEDLDVEDEHE
EQPSNSSVRRAQAVIEDAVATSGVSTLSSTVSHDSQSGHRSLSVQLGRMKIETNRLLEEL
IRKEKELHALLHRAIQEKEQEIKHLKLKSQPIDIPGVPVCHLNSPGTNTEDSELTDWLRE
NGADEDTISRFLAEGYTLVDVLYYVTREDLKCLRLRGGMLCSLWKAIIDFRNTHT
NT seq
4128 nt
NT seq
+upstream
nt +downstream
nt
atgagcgccgacgctggcgagggcatcactttctccgtaccaaccttcgccccctcaggc
ttgtgcccctggcctgagggcggcagctgccggcggggagccacggcggtagccgagggc
gaagagaagcagctaccagcaccgccaccagcgggcagcttctggaacgtggagagcacg
ggcgtcccgggcaccgcaggtcccgccgccggcgcccctgggagcggcgcccctcggtgc
cggggcagctccgggagcgggcccggccgacggaccacagtagcttatgtgatcaacgaa
gcgagccaggggcagctggtggtggctgagagcgaggccctgcagagcctgcgggaggca
tgcgaagcggtgggcgccaccctagagacgctgcattttggcaaactggacttcggggag
acggcggtgctggaccgattttacaacgcagacattgctgtggtggagatgagcgatgcc
ttccggcagccatccttgttctaccaccttggggtgagagagagcttcagcatggccaac
aacatcatcctctactgtgacaccaatgcagactctctgcagtccctcaaggacattatt
tgccagaagaatactatgtgcactgggaactacaccttcgtcccttacatggtgacgccc
cataacaaggtctactgctgtgacagcagcctcatgaagggtttgacagagctcatgcaa
cccaacttggagctgtttcttggacccatctgcctacctcttgtggatcgtttcatccga
ctcttgaagatggcacaagcaagttccagccaatattttcgtgaatctatactcagtgat
atcagaaaagctcgtaatttatacactggtaaagaactggcagctgaattggccagaatt
cggcagcgaatagataatattgaaatcttgacagcagatattgtgatcaatctgttgctg
tcctacagagatatccaggattacgattctattgtgaagctggtggagactttagagaaa
ctgccaacctttgatttggcctcccatcaccatgtgaagtttcattatgcatttgcactg
aataggagaaatctccctggagatagagcaaaagctcttgatattatgatccctatggtg
caaagtgaaggacaggttgcttcagacatgtattgcctcgttggtcgaatctataaagat
atgtttttggattctaatttcacagacactgaaagtagagaccgtggagcttcttggttc
aaaaaggcatttgagtctgagccaacactacagtcgggaattaattatgctgtcctcctc
cttgcagccggccaccagtttgaatcttcctttgagcttcggaaagttggggtgaagcta
agtagccttcttggtaaaaagggaagcttagagaatctccagagctactgggaagttgga
ttttttctgggggctagtgtcttggccaatgaccacgtaagagtcattcaagcatcagaa
aagcttttcaaactgaagacaccagcatggtacctcaagtctatggtagagacaattttg
atctataaacattttgtgaaattgactacagaacagcctgtggccaagcaggaacttgtg
gacttttggatggatttcttggttgaggccacaaaaacagatgttacagtagttaggttt
ccagtattaatattagaaccaaccaaaatctaccaaccttcatatttgtctatcaacaac
gaagtcgaggaaaagacgatatctatttggcacgtgcttcctgacgacaagaaaggcatt
catgagtggaatttcagtgctgcctcagtccggggagtgagtatttctaaatttgaagaa
cgatgctgttttctttatgtgcttcacaattctgatgatttccaaatctatttctgtaca
gaacttcactgtaaaaagttttttgaaatggtgaacaccatcactgaagagaaagggaga
ggcacagaggaaggggactgcgaaggtgactccctggagtatgactacgaatatgatgaa
aatggtgacagagttgttttgggcaaaggcacgtacggaatcgtctacgcaggccgtgac
ctgagcaaccaagtccgaattgcaattaaggaaatcccagaaagggatagcaggtactct
cagcccttgcacgaggaaatagcattgcataagcacctgaagcacaaaaatattgtccag
tatctgggctcgtttagtgaaaatggttttattaaaatctttatggagcaggtcccagga
ggaagtctttctgcactccttcgttccaaatggggccccttaaaagataatgagcaaacg
attggcttttatactaagcaaatactggaaggattaaaatacctccatgacaatcagata
gtccatcgggatataaagggtgacaatgtgttgattaacacctacagcggggtgctcaag
atctctgacttcgggacatccaagaggcttgctggcattaacccatgcactgaaactttt
actggcacccttcaatatatggcaccagaaatcatagataaaggaccacgtggctacggg
aaagcagcagacatctggtctttgggctgtacgatcatcgagatggccacaggaaagccc
ccatttcatgaactgggagaaccacaggcagccatgttcaaggtgggaatgtttaaagtg
caccccgagatcccggagtccatgtctgcagaggcgaaggcattcatactgaaatgtttt
gaaccagaccctgacaagagagcctgtgccaacgacttgcttatcgatgagttcttaaag
gtttcgagcaagaagaaaaagacacaacctaagctttcagctctttcagctggatcaaat
gagtatctcaggagcatctccctgccggtgcccgtcctggtagaagacacaagcagcagc
agcgagtacggttctgtttccccggacaccgagctgaaggcagaccccttctccttcaaa
accagagccaagtcctgcggggaaaaagacggcaaagggatccggacactcttcctgggc
atcccggatgagaactttgaagaccacagtgcacccccatccccggaggagaaggattct
ggtttcttcctgctgaggaaggacagtgagcggcgtgccacactacacaggattctgaca
gaagaccaagacaaggtcgtgaggaacttaatggagtctttagctcagggagccgaagaa
cccaaactcaaatgggagcacatcacaaccctcatcgcaagcctgcgagaatttgtgaga
tccactgaccgaaaaattattgccacgacactatccaagctgaaattagagctggacttc
gacagccatggcatcagccaggtccaggtggtactctttggcttccaggatgctgtcaat
aaagttcttcggaatcataacatcaaacctcactggatgtttgccctggacagcatcatc
cgaaaggcagtgcagacggctattaccattctggttccagaactgaggccacattttagc
cttgcatccgagagtgacaccgctgacccagaagatctggatgtagaggatgagcatgag
gaacagccttctaactcgagtgtccggagagcacaggctgtcatagaagatgccgtggct
acctcaggggtgagcacgctcagctctactgtgtcccacgactcgcagagtggtcaccgg
tcactcagcgtgcagcttggaaggatgaagatagagaccaacagattactggaagaattg
attcggaaagaaaaagaattgcacgcgctccttcatcgagccattcaagaaaaagaacaa
gagattaagcacctgaaacttaaatcccaaccaatagatattcctggggtccctgtctgt
cacctcaattctcctggcacaaatactgaagactctgaacttactgactggctgagagaa
aatggagcagatgaagacactataagtcggtttttggctgagggttatacactggtggat
gttctctactacgttacccgtgaagatttgaaatgcctgagactaaggggcgggatgctg
tgctcactgtggaaggccatcatcgacttccggaacacacacacttga
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integrated database retrieval system
