Ochotona curzoniae (black-lipped pika): 121153373
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Entry
121153373 CDS
T11174
Symbol
HK1
Name
(RefSeq) hexokinase-1 isoform X1
KO
K00844
hexokinase [EC:
2.7.1.1
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz00010
Glycolysis / Gluconeogenesis
ocz00051
Fructose and mannose metabolism
ocz00052
Galactose metabolism
ocz00500
Starch and sucrose metabolism
ocz00520
Amino sugar and nucleotide sugar metabolism
ocz00524
Neomycin, kanamycin and gentamicin biosynthesis
ocz01100
Metabolic pathways
ocz01200
Carbon metabolism
ocz01250
Biosynthesis of nucleotide sugars
ocz04066
HIF-1 signaling pathway
ocz04910
Insulin signaling pathway
ocz04930
Type II diabetes mellitus
ocz04973
Carbohydrate digestion and absorption
ocz05230
Central carbon metabolism in cancer
Module
ocz_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
ocz_M00549
UDP-Glc biosynthesis, Glc => UDP-Glc
ocz_M01015
GDP-Man biosynthesis, Man => GDP-Man
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
121153373 (HK1)
00051 Fructose and mannose metabolism
121153373 (HK1)
00052 Galactose metabolism
121153373 (HK1)
00500 Starch and sucrose metabolism
121153373 (HK1)
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
121153373 (HK1)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
121153373 (HK1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
121153373 (HK1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
121153373 (HK1)
09154 Digestive system
04973 Carbohydrate digestion and absorption
121153373 (HK1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
121153373 (HK1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
121153373 (HK1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ocz04131
]
121153373 (HK1)
Enzymes [BR:
ocz01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.1 hexokinase
121153373 (HK1)
Membrane trafficking [BR:
ocz04131
]
Autophagy
Mitophagy
Other mitophagy associated proteins
121153373 (HK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
UvrD-helicase
Motif
Other DBs
NCBI-GeneID:
121153373
NCBI-ProteinID:
XP_040831810
LinkDB
All DBs
Position
Unknown
AA seq
916 aa
AA seq
DB search
MDSEHSACPVCAGAVAWEPEIDKYLYAMRLSDETLIDIMARFKKEMKNGLSRDSNPTATV
KMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKKQNVHMESEAYETPENIVHG
SGSQLFDHVAECLGDFMEKRNIKDKKLPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVE
GADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEE
LRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMY
MGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGIHNAREILTRLGV
EPSDDDCISVQHVCTIVSFRSANLVAATLGAILSRLRDNKGTPRLRTTVGVDGSLYKTHP
QYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLANFRLTK
EMLLEVKKRMRAEMEAGLSKKTHEKAVVKMLPSFVRSTPDGTEHGDFLALDLGGTNFRVL
LVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFT
FSFPCKQTSLDAGILITWTKGFKATDCVGHDVATLLREAIKRREEFDLDVVAMVNDTVGT
MMTCAYEEPTCEIGLIVGTGCNACYMEEMRNVEMLEGNDGLMCINMEWGAFGDNGCLDDI
RTNYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRGI
FETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAV
VDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGA
ALITAVGVRLRGELGS
NT seq
2751 nt
NT seq
+upstream
nt +downstream
nt
atggactctgagcacagtgcatgcccagtctgtgctggggctgtggcctgggagcctgag
attgacaagtacctctatgccatgcgactctccgacgagaccttgatagatatcatggct
cgcttcaagaaggagatgaagaatggcctctctcgggattctaatccaacagccacagtc
aagatgttgccaacatttgtgaggtccattcctgatggttctgaaaagggggatttcatc
gcactggatcttggtggatcttcctttcggatcctgcgagtgcaagtaaatcacgagaaa
aaacagaacgtccacatggagtctgaggcctatgaaactcctgaaaacatcgtgcacggc
agtgggagccagctttttgatcacgtcgccgagtgcctaggagacttcatggagaaaagg
aacatcaaggacaagaagctgcccgtgggcttcaccttctccttcccttgccgacaatcc
aaaatagacgaggccgtcctgatcacctggacgaagcgatttaaagcgagtggcgtggaa
ggggcagatgtagtcaagctgctgaacaaagccatcaagaagcgaggggactatgatgcc
aacatcgttgccgtggttaacgacacggtggggaccatgatgacatgtggctatgatgac
cagcagtgtgaagtcggcctgatcattggcactggcaccaacgcctgctacatggaggag
ctgaggcacattgacctggtggagggcgacgagggaaggatgtgcatcaacaccgagtgg
ggggcgtttggggatgacggctccctggaagacatccgcactgagtttgacagggagatc
gatcggggctccctcaacccaggaaagcagctgtttgagaagatggtcagtggcatgtac
atgggggaactggtccggctgatcctagtcaagatggccaaggagggcctcctgtttgaa
gggcgaataaccccagagctgctcacccggggcaagtttaacaccagcgatgtgtcggcc
attgagaagaacaaggaaggcatccacaatgccagggagatcctgacccgcctgggcgtg
gagccatccgatgacgactgtatctccgtacagcacgtgtgcaccatcgtctcctttcgc
tcagccaacctggtggctgccacacttggtgccatcttgagccgcttgcgtgataacaag
ggcacgcccaggctgcgcaccacggtcggcgttgatggctctctttacaagacacatcca
cagtattcccggcgtttccacaagaccctgaggcgcctggtgcccgactcggatgtgcgc
ttcctgctgtcggagagtggcagtggcaagggcgctgccatggtgacggctgtggcctac
cgcctggctgagcagcaccggcagatcgaggagaccctggccaacttccgcctcaccaag
gagatgctcctggaggtaaagaagaggatgagggccgagatggaagcggggctaagcaag
aagacacatgaaaaagccgtggtcaagatgctgccctccttcgtccgcagcacccctgat
ggcactgagcacggggacttcctggccctggatcttggaggaacgaatttccgcgtgcta
ctggtaaaaatcaggagtgggaagaaacgcacggtggagatgcacaacaagatatatgcc
attcccatcgagatcatgcagggcacaggcgaggagctctttgaccacatcgtctcctgc
atctccgacttcctggactacatgggcatcaaaggaccccggatgccactgggctttaca
ttctcattcccctgcaagcagacaagcctggatgcgggcatcttgatcacctggaccaaa
ggcttcaaggctacagactgcgtggggcacgatgtggccaccctgctgcgggaagccatc
aaaaggagagaggagtttgatctggacgtggtggccatggtcaacgacacagtgggcacc
atgatgacctgtgcctatgaggagcccacttgcgagatcggacttatcgtcgggacgggc
tgcaatgcctgctacatggaagaaatgcggaacgtcgagatgctggaagggaacgatggg
ctgatgtgcatcaacatggagtggggcgcctttggtgacaacggctgcctggacgacatc
agaaccaactatgatcgactggtggacgaatattccttaaatgccggcaagcagaggtac
gagaagatgatcagcggcatgtacctgggggagattgtccgcaacatcctcatcgacttc
accaagaagggcttcctcttccgggggcagatctccgagccactcaagacacggggcatc
tttgagaccaagttcctctctcagatcgagagtgaccggctcgcgctgctccaggtgcgg
gccatcctccagcagctgggtctgaacagcacctgtgacgacagcatccttgtcaagacc
gtgtgtggggtggtgtcccggagggctgcgcagctgtgcggcgcaggcatggctgccgtg
gtggacaagatccgtgaaaacagggggctggaccgcctcaacgtgactgtgggcgtggat
ggcacactctacaagcttcatccacacttctcccgaatcatgcaccagaccgtgaaggaa
ctgtcgccaaagtgtaacgtgtccttcctcctttcggaagatggcagcggcaaaggggcg
gcgctcatcacggccgtaggcgtgcgactccggggagagctgggcagctaa
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