Ochotona curzoniae (black-lipped pika): 121160667
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Entry
121160667 CDS
T11174
Symbol
BACE2
Name
(RefSeq) beta-secretase 2 isoform X1
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
121160667 (BACE2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
ocz01002
]
121160667 (BACE2)
Enzymes [BR:
ocz01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
121160667 (BACE2)
Peptidases and inhibitors [BR:
ocz01002
]
Aspartic peptidases
Family A1: pepsin family
121160667 (BACE2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
121160667
NCBI-ProteinID:
XP_040842579
LinkDB
All DBs
Position
Unknown
AA seq
514 aa
AA seq
DB search
MGAPARALLLPLLAQWLLRAVPVLAPAPFTLPLRVATATGGGAAPSPRPGTPAAPRADGL
ALALEPAGGAANFLAMVDNLQGDSGRGYYLEMLLGTPPQKLQILVDTGSSNFAVAGAPHP
YVDSYFEADRSSTYRPRGVDVTVRYTQGSWTGSLGEDLVSIPKGFNTSLLVNVATIFESE
NFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVAQARIPDVFSMQMCGAGLPVAGAGT
NGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDS
GTTLLRLPQKVFDAVVEGVARSSLIPEFSDGFWTGSQLACWTNSESPWAYFPKISIYLRD
ENASRSFRLTILPQLYIQPMMGAGLNYECYRFGISASTNALVIGATVMEGFYVVFDRARK
RVGFAASPCAEVAGAPVSEISGPFSTDDLASSCVPAPALPEPTLWLISYALMSVCGAILL
TLIALLLLPLRCRQGARDPEVVNDESSLVRHRWK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgccggcccgggcgctgctgctgccgctgctggcccagtggcttctgcgcgca
gtcccggtgctggcccccgcgcccttcacgttgccgctccgggtggctacggccacgggt
ggcggagctgcgcccagcccccgacccgggactcccgccgcgccccgggccgacggcctg
gcgctcgccctggagcccgcggggggcgccgctaacttcttggccatggtggacaacctg
cagggcgactccggccgcggctactacctggagatgctgctcgggactcccccgcagaag
ctgcagattctcgtggacacgggcagcagtaacttcgccgtggcaggggccccgcatccc
tacgtggattcctactttgaggcggacaggtccagcacttaccgccccaggggcgtggac
gtcaccgtgaggtacacacagggcagctggacgggcagcctcggcgaggaccttgtctcc
atcccgaagggcttcaacacgtccctcctcgtcaacgtcgccacgatttttgagtcggag
aatttttttctgccggggatcaaatggaacggaatactcggtcttgcctacgccacgctg
gccaagccctccagctccctggagacgttcttcgactccctggtggcgcaggcgagaatt
ccagatgtgttctccatgcagatgtgtggggcgggcctgcccgtggctggagccggtacc
aacggaggtagtcttgtcctaggtgggattgaacccagcttgtacaaaggggacatctgg
tataccccgattaaggaggagtggtactaccagattgagatcctgaagctggagatcgga
gggcagagtctgaacctggactgcagggagtacaacgcagacaaggccatcgtggacagt
ggcaccacgctgctgcgcctgccgcagaaggtgttcgacgccgtggtggaaggcgtggcc
cgctcgtctctgatcccggagttctcggacggcttctggactgggtcgcagctggcctgc
tggaccaactcggagagcccgtgggcatacttccctaagatatccatctacctgcgggac
gagaatgccagccgctccttccgcctcaccatcctgccgcagctctacattcagcccatg
atgggggccggcctgaactacgagtgttaccgattcggcatctccgcctccacgaacgcg
ctggtgattggtgccaccgtcatggagggcttctacgtggtcttcgaccgagctcggaag
cgggtgggcttcgcggccagcccctgtgcggaagtcgcaggtgccccggtgtccgagatc
tccgggcctttctcgacggacgacttggccagcagctgcgtcccggccccagccctgccg
gagcccaccctgtggctcatctcgtacgcgctcatgagcgtgtgcggggccatcctgctc
accctcatcgccctgctgctgctgccgctgcgctgtcgccagggggcccgcgatcccgag
gtggtcaacgacgaatcctcgctcgtcaggcatcgctggaaatga
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