Ochotona curzoniae (black-lipped pika): 121163371
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Entry
121163371 CDS
T11174
Symbol
HSD11B1L
Name
(RefSeq) hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz00140
Steroid hormone biosynthesis
ocz00980
Metabolism of xenobiotics by cytochrome P450
ocz01100
Metabolic pathways
ocz05204
Chemical carcinogenesis - DNA adducts
Module
ocz_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
121163371 (HSD11B1L)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
121163371 (HSD11B1L)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
121163371 (HSD11B1L)
Enzymes [BR:
ocz01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
121163371 (HSD11B1L)
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Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Motif
Other DBs
NCBI-GeneID:
121163371
NCBI-ProteinID:
XP_040846845
LinkDB
All DBs
Position
Unknown
AA seq
288 aa
AA seq
DB search
MKLLLLAGLGALFFAYYWDDHFDPASLQGARVLLTGASAGVGEELAYHYARLGSHLVLTA
HTEALLQRVVGNCRKLGALKVFYIAADMASPEAPGHVVQFALDKLGGLDYLVLNHIGGLP
AGTRVRSPKATRWLLQVNFLSYVQLTSLALPSLTDSKGSLVVVSSLLGRVPASFSAPYSA
AKLALDGFFGSLRRELGVQDVNVAITQCVLGLGDRASPSERFRGISRAKAAPGPKAALAV
IRGGATRAAGVFYPWRLHLLCLLRAWWPHPRASWFVRQELNVSAAAAA
NT seq
867 nt
NT seq
+upstream
nt +downstream
nt
atgaagctactactgcttgcagggctgggggccctgttctttgcctactattgggatgac
cacttcgacccagccagcctccagggagctcgggtgctactgaccggggccagcgcgggc
gttggcgaagagttggcttatcactacgcacgcctaggctcccatctggtgctcacggcc
cacaccgaggccttgctgcaaagggtggtcgggaactgccgcaagctgggagcgctcaaa
gttttctacatagcagccgacatggcctcccccgaggccccgggacacgtggtgcagttt
gcactggacaagctaggcgggctggactacctggtgttgaaccacatcggcggtctcccg
gccggaacgcgcgtgcgcagccccaaggcaacccgctggctgctgcaggtgaacttcctg
agctacgtgcagctgacgtcactggcgctgcccagcctgacggacagcaagggctccctg
gtggtggtgtcctcgctgctgggccgcgtgcccgcgtccttctcggccccctactcggcg
gccaagttggccctggacggcttcttcggctccctgcggcgggagctgggcgtgcaggac
gtgaacgtggccatcacccagtgcgtcctgggcctcggcgaccgcgcttcgccctccgag
cgcttcaggggcatctccagagccaaggcggccccgggacccaaggctgccctggccgtg
atccgcggcggcgccacgcgagcggccggggtcttctacccgtggcgcctgcacctgctg
tgcctgctgcgggcctggtggccgcacccgcgggcctcgtggttcgtgcgccaggagctc
aacgtctcggctgcagctgcggcctga
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