Ochotona curzoniae (black-lipped pika): 121165104
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Entry
121165104 CDS
T11174
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz04137
Mitophagy - animal
ocz04140
Autophagy - animal
ocz04141
Protein processing in endoplasmic reticulum
ocz04210
Apoptosis
ocz04932
Non-alcoholic fatty liver disease
ocz05010
Alzheimer disease
ocz05012
Parkinson disease
ocz05014
Amyotrophic lateral sclerosis
ocz05020
Prion disease
ocz05022
Pathways of neurodegeneration - multiple diseases
ocz05160
Hepatitis C
ocz05162
Measles
ocz05168
Herpes simplex virus 1 infection
ocz05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
121165104 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
121165104 (EIF2AK3)
04137 Mitophagy - animal
121165104 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
121165104 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
121165104 (EIF2AK3)
05162 Measles
121165104 (EIF2AK3)
05168 Herpes simplex virus 1 infection
121165104 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
121165104 (EIF2AK3)
05012 Parkinson disease
121165104 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
121165104 (EIF2AK3)
05020 Prion disease
121165104 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
121165104 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
121165104 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
121165104 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ocz01001
]
121165104 (EIF2AK3)
Enzymes [BR:
ocz01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
121165104 (EIF2AK3)
Protein kinases [BR:
ocz01001
]
Serine/threonine kinases: Other
PEK family [OT]
121165104 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Beta-prop_ACSF4
Kdo
ABC1
DUF7670
Motif
Other DBs
NCBI-GeneID:
121165104
NCBI-ProteinID:
XP_040849495
LinkDB
All DBs
Position
Unknown
AA seq
1116 aa
AA seq
DB search
MERAVRPGSLVWALLLPLLLALTVGTGAAGRARDLPAPRTDAAFGLGAAAAPTSAARMPA
AGAVAGAEVTVEDAEALPATAGEPEPRGPDPDDEAELRSPGRSLVIISTLDGRIAALDPE
NHGKKQWDLDVGSGALVSSSLSKPEVFGNKVIIPSLDGDLFQWDRDRESMETVPFTVESL
LESSYKFGDDVVLVGGKSLTTYGLGAYSGKVRYICSALGCRRWDGEDLEEEEDILLLQRT
QKTVRAVGPRSGNEKWNFSVGHFELRYIPDMETRAGFIESTFKPSENKEESNIISDVEEQ
EAGTMDTVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLVKDGKVIPISLFDDTSY
TPNQEVLEEEEDIVEAARGATESSVYLGMYRGQLYMQSSVRISEKFPTSPKALESVNNDN
AIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQYPYDNGYY
LPYYKRDRNKRSTQITVRFLDNPSYSKNIRRKDPVLLLHWWKEILGTILFCIIATTFIVR
RLFHPHPHRQRKESETQCQTENKYDAVSGEASDSSWNDLKTSGYISRYLTDFEPIQCLGR
GGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVRYFNAWLEA
PPEKWQEKMDEIWLKDESTDWPLSSPSPMDAPSVKIRRVDPFSTKEHIEIIAPSPQRSRS
FSVGISCGQTSSSESQFSPLEFSGTEQGDVSVSVGAASNLPDSCLTDCDVEDGTMDGNDE
GHPFELCPSEASPYSRSRERTSSSIVFEDSGCDNASSKEEPRARRLRLGSHCANKLSILQ
HSSSSSSASEPTLSVSPPRPTTLSLDLTKNTTEKLQPSSPKVYLYIQMQLCRKENLKDWM
NRRCTLEERERSTCLHIFLQITEAVDFLHSKGLMHRDLKPSNIFFAMDDVVKVGDFGLVT
AMDQDEEEQAVLTPMPAYATHTGQVGTKLYMSPEQVHGNNYSHKVDIFSLGLILFELLYP
FSTQMERDRTLSDVRNLKFPSLFTQKYPQEHVMVQGMLSPCPTDRPEAANIIENAVFEEL
ELPGKTMLRQRSRSASSSGTKHSRQPSSSQGPLPGT
NT seq
3351 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccgtgcgcccggggtcgctggtgtgggcgctgctgctgcccctgctgctg
gcgctgaccgtgggcaccggggccgcggggcgtgcccgggacctgcccgcgcccagaacg
gacgctgcgttcggcctgggggccgcggccgctcccacgtcggccgcgcgaatgccggcg
gccggagccgtggccggggccgaggtgacggtggaggacgccgaggcgctccctgcgact
gcgggcgagccggagccgcggggaccggatcccgacgacgaggctgagctgcgatcgcca
ggcagatcattagtgattatcagcactttagatggcaggattgctgccttggatcctgag
aatcatggcaaaaagcagtgggatttggatgttggatctggtgccttggtttcatccagc
cttagcaaaccagaggtgtttgggaataaagtaatcattccttccctggacggagacctc
ttccagtgggaccgagaccgggagagcatggaaaccgttcctttcacagttgaatccctt
ctcgaatcttcttacaaatttggagatgatgtggttttggtgggaggaaagtctctcact
acatatggactcggtgcctacagtggaaaggtgaggtacatctgctcagctctgggttgt
cgccgatgggacggcgaggacctggaggaggaggaggacatcctgctgctgcagcggacc
cagaagaccgtgcgcgccgtcgggcctcgcagcggcaacgagaagtggaatttcagtgtt
ggccactttgaacttcggtatattccagacatggaaactagagccggatttattgaaagc
acctttaagcccagtgagaacaaagaagagtctaacattatttcagatgtggaagaacag
gaagctggcacgatggacacggtgataaaggtctcggttgctgactggaaggtcatggcg
ttcagcaagaagggaggacatctggagtgggagtaccagttttgtactccgattgcatcc
gcctggctggtgaaggatgggaaagtcattcccatcagccttttcgacgataccagttac
acacctaaccaggaagtcttggaagaggaggaagacattgtggaagcggcccgaggagcc
acggagagcagtgtttatttggggatgtatagaggccagctgtatatgcagtcatctgtc
agaatttcagaaaagtttcctacaagtcccaaagccttggaatccgtcaataacgacaat
gcaattattcctctgccaacaatcaaatggaagcccttaattcattccccttccaggact
cccgtcttggtgggatctgatgaatttgacaaatgcctcagtaacgataagttttctcac
gaggaatacagcaatggggcactttcgattctacagtatccatatgataacggatactat
ctgccatactacaagagggacaggaacaagcggagcacccagattactgtgagattcctg
gacaaccccagctacagcaagaacatccgccggaaggaccccgtgctcctgctgcactgg
tggaaggagatcctggggaccatcctgttctgtatcatagcaacaaccttcatcgtgcgc
cggctcttccatcctcatccccacagacaaaggaaggagtctgaaactcaatgtcagacc
gaaaataaatacgacgctgtaagtggggaagccagtgacagtagctggaatgatctgaaa
acctctggctacatatcccgatacctaacagactttgaaccaatccagtgcctgggccgt
gggggcttcggggttgtctttgaagccagaaacaaagtagatgactgcaattacgccatc
aagaggatccggctccccaacagggaactggctcgggaaaaggtaatgcgagaagtgaag
gcccttgccaagcttgaacacccgggcatagtcaggtatttcaatgcctggcttgaagcc
cctccagagaaatggcaagaaaaaatggatgagatctggctgaaagatgaaagcacagac
tggccactcagctcccccagcccgatggacgccccctcagttaaaattcgcagagtggat
cctttctctacaaaagaacacattgaaatcatagctccttccccgcaaagaagcaggtcc
ttctccgtcgggatctcctgcggccagacgagttcgtcggagagccagttttccccactg
gagttctccggaacagagcagggagatgtcagtgtgtctgtgggtgcggcctccaacctc
ccggacagttgccttacagactgcgatgtggaagatgggactatggatggcaacgacgag
ggccacccctttgaactctgtccctcggaagcctctccctacagcaggtccagggagagg
acctcctcgtctatagtgtttgaggattctggctgcgacaacgcatccagcaaagaggag
cccagagcccggcggctgcggctcggcagccactgtgctaacaaactgagcatcctccag
cactccagcagcagcagctctgcttcggaacctaccctgtccgtttcccctcccaggccc
accacattaagtctagatctcacaaagaacactactgagaaactgcagcccagttccccc
aaggtgtacctgtacatccagatgcagctgtgccggaaggaaaacctcaaagactggatg
aacaggcgctgcaccctggaggagagggagcggagcacgtgtctgcacatcttcctgcag
atcactgaggccgtggacttcctgcacagtaaaggactcatgcacagggacctcaagcct
tccaacatattctttgcaatggacgacgtggtcaaggttggagactttggattagtgact
gcaatggaccaggacgaggaagagcaggcggttttgactccgatgccagcgtacgccaca
cacacaggacaagtagggaccaaactctatatgagcccagagcaggttcatggcaacaac
tactctcataaagtggacatcttttccttgggcctgattctgtttgagctgctgtacccc
ttcagcactcagatggagagagacaggaccttatctgatgtgagaaatctcaaatttcca
tcactgtttactcagaagtatcctcaagagcacgtgatggtccaaggcatgctgtccccg
tgccccacggaccggcccgaagccgcaaacatcatcgaaaacgccgtgtttgaggagctg
gagttgccagggaaaaccatgctccggcagaggtcacgctccgcgagctcatcgggaaca
aaacactcaaggcagcccagcagctcgcagggccctctgccaggcacctag
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