Ochotona curzoniae (black-lipped pika): 121171948
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Entry
121171948 CDS
T11174
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
ocz Ochotona curzoniae (black-lipped pika)
Pathway
ocz00061
Fatty acid biosynthesis
ocz00620
Pyruvate metabolism
ocz00640
Propanoate metabolism
ocz01100
Metabolic pathways
ocz04152
AMPK signaling pathway
ocz04910
Insulin signaling pathway
ocz04920
Adipocytokine signaling pathway
ocz04922
Glucagon signaling pathway
ocz04931
Insulin resistance
ocz04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
ocz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
121171948 (ACACB)
00640 Propanoate metabolism
121171948 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
121171948 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
121171948 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
121171948 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
121171948 (ACACB)
04922 Glucagon signaling pathway
121171948 (ACACB)
04920 Adipocytokine signaling pathway
121171948 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
121171948 (ACACB)
04931 Insulin resistance
121171948 (ACACB)
Enzymes [BR:
ocz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
121171948 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
121171948 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
121171948 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
121171948
NCBI-ProteinID:
XP_040859614
LinkDB
All DBs
Position
Unknown
AA seq
2448 aa
AA seq
DB search
MVLLLFLSGLIISCLTFSWLKFWGKMTDSQPVTSSSPSGNSNLSQEPLAAAEGSGEPPQV
NGKPKPAPHRGTRDAHAAGRRRNSIPTSRQKLPKPPSSPNNVLPSPETQAGKTGTQQLDV
PDANGLPGPARPQGLAASAPSREDEKQEHIKRQLMTNFILGSFDDNSSDEDSGATAFRIS
SRKGSRASLGILSPEGLPTLGEAETQMRPSMSGLHLVRRGREHKKLDLHRDFTVASPAEF
VTRFGGNRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEY
IKMADQYVPVPGGPNNNNYANVELIMDIAKRIPVQAVWAGWGHASENPKLPELLCKHGIA
FLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVAWEEDGLQQGRVIHVPEDVYD
RGCVKDVEEGLEAAEKIGFPLMIKASEGGGGKGIRKAESAEDFPMLFRQVQSEIPGSPVF
LMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPAVFEFMEQC
AVRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMG
VPLHRLKDIRLLYGESPWGVTPICFDTPANPPLARGHVIAARITSENPDEGFKPSSGTVQ
ELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDF
RTTVEYLINLLETESFQSNDIDTGWLDHLIAEKVQAEKPDVMLGVVCGALNVADAMFRTC
MTDFLHSLERGQVLPADSLLNIVDVELIYGGVKYILKVARQSLTMFVLIMNNCHIEIDAH
RLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLMQYTI
EDGGHVEAGSSYAEMEVMKMIMTLNVQESGRVKYIKRPGAVLEAGCVVARLELDDPSKVR
PAEPFRGELPAQQTLPILGEKLHQVFHNVLENLTNVMSGYCLPEPIFSKKLKEWVQKLMM
TLRHPSLPLLELQEIMTSVAGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQQIATILDC
HAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKTVVLDLLRRYLQVEHHFQQAHYD
KCVIQLREQFKPDMSQVLDCIFSHAHVAQKNQLVTMLIDELCGPDPSLSDELTSILSELT
QLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPDNLKKLILSE
TTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSS
HPNRMALPVSMSNPDLLRHSTELFMDNGFSPLCQRMGAMVAFRRFEDFTRNFDEVISCFA
NMPKDTPLFSKASNSLYPEDDGKSPWEEPIHILNVAIEHADHLDDEALVPIFRTFVQSKK
NILKDCGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDL
AAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLL
EAMDELEVAFNNTTVRTDCNHIFLNFVPTVIMDPLKIEESVRSMVMRYGSRLWKLRVLQA
EVKINIRQSTSGTALPIRLFITNESGYYLDISLYKEVTDPRSGDIMFHSFGNKQGPQHGM
LINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGTPDKYPKDILTYTELVL
DSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRVVVVISNDITFRIGSFGQGEDLLF
TRASELARAEGIPRIYLAANSGARIGLAEEVKHMFQVAWVDPEDPHKGFKYLYLTPQDYT
KISSLNSVHCKHVEEGGESRYVITDIIGKDDGLGVENLRGSGMIAGESSLAYDEIVTISM
VTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMHYNG
VSHVTVPDDFEGVFTILEWLSYVPKDNRSPVPIITPSDPIDREIEFFPSRAPYDPRWMLA
GRPHPTLKGTWQSGFFDQGSFKEIMSPWAQTVVTGRARLGGIPVGVIAVETRTMEVAIPA
DPANLDSEAKVIQQAGQVWFPDSAYKTAQAIKDFNREKLPLMLFANWRGFSGGMKDMYDQ
VLKFGAYIVDGLRQYQQPVLIYIPPYAELRGGSWVVVDPTINPLCIEMYADKESRGGVLE
PEGTVEIKFRKKDLTKAMRRIDPTYRKLMEQLGSAQLSEQDRRDLEGRLKAREELLLPIY
HQVAVQFADLHDTPGRMLEKGVVSDVLEWRTSRTFLYWRLRRLLLEDQVKQEILRASGEL
SHVHIQSMLRRWFVETEGPVKAYLWDNNEVVVRWLEQHWQEEDGLRSTIRENIKYLKRDS
VLKTIRKLVQENSEVAMDCIVHLSQHLSPAERAQLVQLLSTLESPAST
NT seq
7347 nt
NT seq
+upstream
nt +downstream
nt
atggtcttgctgcttttcctgtctggcctgattatttcctgcctgaccttttcctggtta
aagttctgggggaagatgacggactctcagccagtcaccagcagttccccatctgggaac
tccaacctgagccaggagcccttggcagctgcagaaggctcaggggagcccccgcaggtc
aatggcaaacctaagccggccccccatcggggcaccagggatgcccatgctgctggccgc
aggagaaactcaatcccaacctcgcgacagaagctccccaaacccccctcttctcccaac
aacgtattaccctccccagaaacccaggccggcaagacggggactcaacaactggatgtc
ccagatgccaatggactgcctggcccagctcggccccagggcctggcagccagtgcccca
tcccgggaggatgagaagcaagaacacatcaagagacagctgatgaccaacttcatcctg
ggctcctttgacgacaactcctctgatgaagattcgggtgccactgccttccgcatctcg
tccaggaagggcagccgggccagcctggggatcctgtcccctgaggggcttccaacacta
ggagaagctgagacccaaatgaggccaagcatgtccggtctgcacctggtgaggaggggc
cgggagcacaagaagctggacctacatagagacttcactgtggcttccccagctgagttt
gtcacacgctttgggggcaaccgggtcatcgagaaggtactcatcgccaacaacggcatc
gcagctgtgaagtgcatgcgctccatccgcaggtgggcctacgagatgtttcgcaatgag
cgggccatccggtttgtagtcatggtgaccccagaggacctcaaggccaacgcagaatac
atcaagatggcggaccagtacgtccctgtcccaggaggacccaataacaacaactacgcc
aacgtggagctcatcatggacattgccaagaggatccctgtgcaggccgtgtgggctggc
tggggccatgcctccgaaaaccccaagctgccggagctactgtgcaagcatgggattgcc
ttcttaggtccccccagtgaggccatgtgggccttgggagacaagatcgcctccaccatc
gtggcccagaccctgcagattcccacgctgccctggagtggaagtggtttgacggtggcg
tgggaggaggacgggctgcagcaggggcgggtcatccacgtccctgaagacgtctatgac
cgaggctgcgtgaaagatgtggaggagggcttggaggcggctgagaagattggctttcca
ctgatgatcaaggcctctgagggtggcggtggcaagggcatccggaaggccgagagcgca
gaggacttccccatgctcttcagacaggtgcagagtgagatcccaggctcacctgtgttt
ctcatgaagctggcccagcatgcacggcacctagaggtgcagatccttgctgaccagtac
gggaatgccgtgtccctcttcgggcgtgactgctctatccagcggcgacaccagaagatc
atcgaggaggcgccggccaccattgccacgccagctgtgttcgagttcatggaacagtgt
gctgtccgcctggccaagactgtgggctacgtgagtgcggggacggtcgagtatctctac
agccaggacggcagcttccacttcctggagctgaaccctcgtctgcaggtggagcatccc
tgcacagagatgattgccgacgtcaacctgccggctgcccagctgcagatcgccatgggg
gtaccgctgcaccggctgaaggacatccggctcctgtacggagaatcaccttggggggtg
acacccatttgtttcgacacccctgccaaccctcccctcgcccgaggccacgtcatcgca
gccaggatcaccagtgagaaccctgatgaggggtttaagccgagctcagggaccgtgcag
gagctgaacttccgcagcaacaagaatgtatggggctacttcagcgtggcagccgccggg
ggcctgcacgagtttgccgattcccagtttggccactgcttctcctggggagagaaccgg
gaagaggccatttcgaacatggtggtggcgctgaaggagctgtccatccgtggcgacttc
aggaccacagtggagtatctcatcaacctcctggagaccgagagcttccagagtaacgac
atcgacacgggctggctggaccacctcatcgccgagaaagtgcaggctgagaaacccgac
gtcatgctcggggtggtgtgcggggctttgaacgtggccgatgcaatgtttagaacctgt
atgacagacttcttgcactccctggaaaggggccaggtccttcccgccgattccctgctg
aacatcgtggatgtggagttaatttatggaggtgtcaagtacatcctcaaggtggcccgg
cagtctctgaccatgttcgtactcatcatgaacaactgccacatcgagatcgacgcccac
cggctcaacgatggggggctgctgctctcctacaacggcagcagctacaccacctacatg
aaggaggaggtggacagttaccggatcaccattggcaacaagacatgcgtgttcgagaag
gagaacgaccccacggtgctgaggtcgccgtcagcggggaagctgatgcagtatacaata
gaggatgggggccacgtggaggccggcagcagctatgctgagatggaggtgatgaagatg
atcatgacgctgaacgtgcaggaaagcggccgggtgaagtacatcaagcggccaggggcc
gtgctggaagccggctgcgtggtggctcggctggagctcgatgacccttctaaagtgcgc
ccggctgagcccttcagaggagagctccccgcccagcaaactctgcccatccttggggag
aagctgcatcaggttttccacaatgttctagaaaacctgaccaacgtcatgagtggctac
tgtctcccagagcccatattcagcaaaaagctcaaggagtgggtgcagaagctgatgatg
acactccggcacccgtcgctgccgctgctggagctgcaggagatcatgacgagcgtggcg
ggccgcatcccagcacccgtggagaaggcggtccgcagggtgatggcccagtacgccagc
aacatcacctcggtgctgtgccagttccccagccagcagatagccaccatcctggactgc
cacgcggccacactgcagcgcaaggccgaccgtgaggtcttcttcatgaacacacagagc
attgtgcagctggttcagaggtaccgcagcggcacccgcggctacatgaagacagtggtg
ttggacctcctgcgacgttatctgcaagtggagcaccatttccaacaagcccactacgac
aagtgcgtcatccagctcagagagcagttcaagccggacatgtcccaggtgctggactgc
atcttctcacacgcgcacgtggcccagaagaaccagctggtgaccatgctgatcgacgag
ctgtgtggccccgacccctccctgtcggatgagctgacctccatcctcagtgagctcacg
cagctgagcaagagcgagcactgcaaagtggccctcagagcccgacaggtgctgatcgcc
tctcacctgccctcctacgagctgagacacaaccaggtcgagtccatcttcctgtctgcc
attgacatgtacggccaccagttctgcccggacaacctcaagaaactgatcctttcagag
acgaccatcttcgacgtcctgcccaccttcttctaccacgccaacaaggtggtgtgcatg
gcctccctggaggtgtacgtgcgaaggggctatatcgcctacgagctgaacagcctgcaa
caccggcagctgccggatggcacgtgcgtggtggaattccagttcatgctgccctcttcc
cacccgaaccggatggccttgcccgtgagcatgagcaaccccgacctgctgaggcacagc
acggagctcttcatggacaacggcttctccccactgtgccagcggatgggcgccatggtc
gccttcaggcggttcgaggatttcaccaggaactttgatgaggtcatctcctgcttcgcc
aacatgcccaaggacacgccgctcttcagcaaggccagcaactccctctaccctgaggac
gatggcaagagcccctgggaagaacccatccacatcctgaacgtggccatcgagcacgca
gaccacttggatgacgaggcgctggtgcccatcttccgcaccttcgtgcagtccaagaag
aatatcctcaaggattgcggactccgaagaatcacattcctcattgcccaggagaaagaa
ttccccaagttcttcactttcagagcgagagatgagtttgcggaggaccgaatttaccgc
cacttggagcctgccctggccttccagctggagctcagccgcatgcgcaacttcgacctg
gccgccgtaccgtgtgccaaccacaagatgcacctgtacctgggtgccgccaaggtcaag
gaaggggtggaggtgaccgaccacagattcttcatccgcgccatcatcaggcactcggac
ctgatcaccaaggaggcgtcctttgagtacctacagaacgagggcgagcggctgctcctg
gaggccatggacgagctggaggtggccttcaacaacaccactgtgcgcactgactgcaac
cacatcttcctcaacttcgtgcccaccgtcatcatggaccccctgaagatcgaggaatcg
gtgcgctccatggtgatgcgctacggcagccggctgtggaagctccgtgtgctgcaagcc
gaggtcaagatcaacatccgccagagcaccagcggcacagccctgcccatccgcctcttc
atcaccaatgagtctggctactacctggacatcagcctctacaaggaagtgacggacccc
agatctggcgatatcatgtttcactccttcggcaacaagcaagggccgcagcacgggatg
ctgatcaacacgccctatgtcaccaaggacctgctgcaggccaagcgcttccaggcccag
tcgctgggcaccacctacgtgtatgacttcccggaaatgttcagacaggccctctttaag
ctgtggggcactccagacaagtatcccaaagacatcctgacctacacagagctggtgctg
gattcccagggccagctggtagagatgaaccggcttcccggtggcaacgaggtcggcatg
gtggctttcaagatgaggttcaagacccaggaatacccggaagggcgggtcgtggtggtc
atcagcaatgacatcaccttccgcattgggtcctttggccaaggggaggacctgctgttc
acacgggcgtctgagctggccagggccgagggcatccccaggatctacctggcggccaac
agcggggcccgcatcggcctggccgaggaggtcaagcacatgttccaggttgcctgggtg
gaccccgaggacccacacaagggatttaaatacctgtacctgaccccgcaagactacacc
aagatcagctccctcaactctgtgcactgcaagcacgtcgaggaaggaggagaatccagg
tatgtcatcacggacatcatcgggaaggatgacggcctgggcgtggagaacctgcggggc
tcgggcatgatcgcgggggagtcctccctggcttatgatgagatcgtcaccatcagcatg
gtgacctgccgggcccttggcatcggggcatacctggtgaggctgggccagcgcgtgatc
caggtggagaactcccacatcatcctcacaggagccagcgctctcaacaaggtgctgggg
agagaggtctacacatccaacaaccagctgggcggcgtgcaaatcatgcattataacggt
gtctcccacgtcaccgtgccggatgacttcgagggggtctttaccatcctggaatggctg
tcctatgtgccaaaggataaccgcagcccagtcccgatcatcacccccagcgaccccatt
gacagagaaatcgaattcttcccatccagggcaccctacgacccccgctggatgctcgcg
ggaaggccccaccccactctgaagggcacctggcagagtgggttcttcgaccagggcagt
ttcaaggagatcatgtcgccttgggcccagacggtggtgacgggacgagccaggctaggg
ggcatccctgtgggagtgatcgccgtggagacgcggaccatggaggtggccattccggca
gaccctgccaacctggactccgaggccaaggtgatccagcaggccggccaagtgtggttc
ccagactcagcctacaaaaccgcccaggccatcaaggacttcaaccgggagaaactgcca
ctgatgctctttgccaactggaggggtttctccggcggcatgaaagacatgtacgaccag
gtgctcaagttcggcgcctacattgtggacggcctcaggcagtaccagcagcccgtgttg
atctacatcccgccctatgccgagctccgcggcggctcctgggtggtggtggaccccacc
atcaatccgctgtgcatagagatgtacgccgacaaggagagcagagggggtgtcctggag
ccagaaggcacggtggagattaagttccgaaagaaagacctgacaaaggcaatgaggagg
atcgacccgacctataggaagctcatggaacagctgggttcagcccagctctccgagcag
gaccgcagggacctggagggccggctgaaggcccgcgaggagctgctgctccccatctac
caccaagtggcggtgcagttcgcagatctccatgacacgcctggccgcatgctggagaag
ggcgtggtctccgatgtcctggagtggaggacctcgcgtaccttcctgtactggcgccta
cgtcgcctcctcctggaggaccaggtcaagcaggagatcctgcgggccagcggcgagctg
agccatgtgcacatccagtccatgctgcgccgctggttcgtggagaccgagggccctgtg
aaggcctacctatgggacaacaatgaggtggtagtgaggtggctggagcagcactggcag
gaggaggacggcttgcgctccaccatccgtgagaacatcaagtacctgaaacgagactcc
gtcctcaagactatccgaaagcttgttcaagagaactccgaggtagccatggactgcatt
gtgcacctgagccagcatttgagtccagccgagcgcgcccagctggttcagctgctgtcc
accttggagagcccggcctccacttga
DBGET
integrated database retrieval system
