Oryx dammah (scimitar-horned oryx): 120854212 Help Entry 120854212         CDS       T07255                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism oda  Oryx dammah (scimitar-horned oryx) Pathway oda04064   NF-kappa B signaling pathway oda04380   Osteoclast differentiation oda04650   Natural killer cell mediated cytotoxicity oda04658   Th1 and Th2 cell differentiation oda04659   Th17 cell differentiation oda04660   T cell receptor signaling pathway oda05135   Yersinia infection oda05166   Human T-cell leukemia virus 1 infection oda05235   PD-L1 expression and PD-1 checkpoint pathway in cancer oda05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:oda00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     120854212 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     120854212 (LCK)    04660 T cell receptor signaling pathway     120854212 (LCK)    04658 Th1 and Th2 cell differentiation     120854212 (LCK)    04659 Th17 cell differentiation     120854212 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     120854212 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     120854212 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     120854212 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     120854212 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     120854212 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:oda01001]     120854212 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:oda03036]     120854212 (LCK) Enzymes [BR:oda01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      120854212 (LCK) Protein kinases [BR:oda01001]  Non-receptor tyrosine kinases   SRC family    120854212 (LCK) Chromosome and associated proteins [BR:oda03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     120854212 (LCK) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH2_1 Haspin_kinase Kdo SH3_16 Motif Other DBs NCBI-GeneID:  120854212 NCBI-ProteinID:  XP_040083968 LinkDB All DBs Position Unknown AA seq 509 aa AA seqDB search MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKTTLPMRNGSEVRDPLVTYEGSNPPASP LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQNGEWWKAQSLTTGQEGFIPFNFVAKAN SLEPEPWFFKTLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQTQGEVVKH YKIRNLDKGGFYISPRVTFPGLHELVRHYMNTSDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTSEGIKLTINKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSHSLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMMLCWKER PEDRPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtagctgcagctcaaacccagaagatgactggatggaaaacatcgatgtttgt gaaaactgccactaccccatagtcccactggatggcaagaccacgctgcctatgcggaat ggctctgaagtgcgtgatccactggtcacctacgagggatccaaccccccagcttctcca ctgcaagacaacctggttatcgccctgcacagctatgagccttctcacgatggagacctg ggcttcgagaagggtgaacagctccgtatcctggagcagaacggcgagtggtggaaggcg cagtccctgaccaccggccaggaaggtttcatccccttcaactttgtggccaaagcgaac agcctggagcccgaaccctggttcttcaagaccctgagccgcaaggacgcggagaggcag ctcctggcgccggggaacacgcacggctccttcctgatccgggagagcgagagcacggcg ggatcgttttcactgtcggtccgggacttcgaccagacccagggagaagtggtgaaacat tacaagatccggaacctggacaaaggcggcttctacatctcgccccgcgtcactttcccc ggcttgcacgagttggtccgccattacatgaatacttcggacgggctgtgcacacggttg agccgcccctgccagacccagaagccccagaagccgtggtgggaggatgagtgggaggtt cccagggagactctgaagctggtggagcggctgggggctggccagttcggagaggtgtgg atggggtactacaacgggcacacgaaggtggcagtcaagagcctgaagcagggcagcatg tcccccgatgccttcctggccgaggccaacctcatgaagcagctgcaacaccagcggctg gtccggctttacgcggtggtcacccaggagcccatctacatcatcacggaatatatggag aacggaagcctggtggattttctcaagacctccgaaggcatcaagctgactatcaacaaa ctcttggacatggcagcccaaattgcagagggcatggcattcattgaagagcggaattat atccaccgtgacttgagggctgccaacatcctggtgtcccatagcctgagctgcaagatc gcagactttggtctagcacgcctcattgaggacaacgagtacacagccagggagggtgcc aagtttcccattaagtggacagcaccagaagccattaactacgggacattcaccataaag tcggacgtgtggtctttcgggatcctactgacggagattgtcactcatggtcgcatccct tacccagggatgaccaatcctgaggtgattcagaacctggagcgaggctaccgcatggta cggcctgacaactgcccggaggagttgtaccagcttatgatgctgtgctggaaggagcgc ccggaggaccggcccacctttgactacctgcgcagcgtgttggaggacttcttcacggcc acagagggccagtaccaaccccagccctga

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