Oryx dammah (scimitar-horned oryx): 120854621 Help Entry 120854621         CDS       T07255                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism oda  Oryx dammah (scimitar-horned oryx) Pathway oda01524   Platinum drug resistance oda04115   p53 signaling pathway oda04210   Apoptosis oda04215   Apoptosis - multiple species oda04217   Necroptosis oda04620   Toll-like receptor signaling pathway oda04621   NOD-like receptor signaling pathway oda04622   RIG-I-like receptor signaling pathway oda04623   Cytosolic DNA-sensing pathway oda04625   C-type lectin receptor signaling pathway oda04657   IL-17 signaling pathway oda04668   TNF signaling pathway oda04932   Non-alcoholic fatty liver disease oda04936   Alcoholic liver disease oda05010   Alzheimer disease oda05016   Huntington disease oda05022   Pathways of neurodegeneration - multiple diseases oda05132   Salmonella infection oda05134   Legionellosis oda05142   Chagas disease oda05145   Toxoplasmosis oda05152   Tuberculosis oda05160   Hepatitis C oda05161   Hepatitis B oda05162   Measles oda05163   Human cytomegalovirus infection oda05164   Influenza A oda05165   Human papillomavirus infection oda05167   Kaposi sarcoma-associated herpesvirus infection oda05168   Herpes simplex virus 1 infection oda05169   Epstein-Barr virus infection oda05170   Human immunodeficiency virus 1 infection oda05200   Pathways in cancer oda05203   Viral carcinogenesis oda05416   Viral myocarditis oda05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:oda00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     120854621 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     120854621 (CASP8)    04215 Apoptosis - multiple species     120854621 (CASP8)    04217 Necroptosis     120854621 (CASP8)    04115 p53 signaling pathway     120854621 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     120854621 (CASP8)    04621 NOD-like receptor signaling pathway     120854621 (CASP8)    04622 RIG-I-like receptor signaling pathway     120854621 (CASP8)    04623 Cytosolic DNA-sensing pathway     120854621 (CASP8)    04625 C-type lectin receptor signaling pathway     120854621 (CASP8)    04657 IL-17 signaling pathway     120854621 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     120854621 (CASP8)    05203 Viral carcinogenesis     120854621 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     120854621 (CASP8)    05161 Hepatitis B     120854621 (CASP8)    05160 Hepatitis C     120854621 (CASP8)    05164 Influenza A     120854621 (CASP8)    05162 Measles     120854621 (CASP8)    05168 Herpes simplex virus 1 infection     120854621 (CASP8)    05163 Human cytomegalovirus infection     120854621 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     120854621 (CASP8)    05169 Epstein-Barr virus infection     120854621 (CASP8)    05165 Human papillomavirus infection     120854621 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     120854621 (CASP8)    05134 Legionellosis     120854621 (CASP8)    05152 Tuberculosis     120854621 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     120854621 (CASP8)    05142 Chagas disease     120854621 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     120854621 (CASP8)    05016 Huntington disease     120854621 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     120854621 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     120854621 (CASP8)    05416 Viral myocarditis     120854621 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     120854621 (CASP8)    04932 Non-alcoholic fatty liver disease     120854621 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     120854621 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:oda01002]     120854621 (CASP8) Enzymes [BR:oda01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      120854621 (CASP8) Peptidases and inhibitors [BR:oda01002]  Cysteine peptidases   Family C14: caspase family    120854621 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED AIG1 ERM_C PYRIN Motif Other DBs NCBI-GeneID:  120854621 NCBI-ProteinID:  XP_040084736 LinkDB All DBs Position Unknown AA seq 488 aa AA seqDB search MDLTQCLYKIGEQLGSDDLAALKFLSRDHIPYRKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFQVNRLDLLLDYLDTSEEEMKRELQIPGRAQISAYRILLFQISEDVNKVELKDF KFFLSQEIAKCKLDDDMTLLDIFVEMEKRTILGENNLDTLKRICEQVNKSLLKKIYDYEE LRKDSERRMRLERDPDEFSNDMSQSLPEEGSSELLAIADSLAELDSELQTSDTVYRMTSK PRGYCLIFNNYDFSIAREQVPELHSLKDRNGTHLDAEALEKTFSELHFEIVHYRDQTAKG ICEVLKSYQKKDHRTKDCFICCILTHGNKGTIYGSDGQEAPIYELTSYFTGSKCPSLVGK PKIFFIQACQGDKYQRGIAVETDSEQMEAYLEVDSSPHKRYIPDEADFLLGMATVNNCVS YRSILKGTWYIQSLCQNLRERCPRGEDILTILTKVNFEVSKKDDKQNMGKQMPQPTFTLR KKLFFPLN NT seq 1467 nt NT seq  +upstreamnt  +downstreamnt atggatctcacccagtgtctctataaaattggggagcagctgggcagtgacgacctggct gccctcaagttcctaagccgggaccacatcccatataggaagcaggaacccattaaggat gccctgatgctattccagaggctccaagaaaagagaatgttggaggaaagcaatctgtcc ttcttgaaggagctgcttttccaagtgaatagactggatctgctgcttgactacttggac accagtgaggaggagatgaagagggagcttcagatacctggcagggcccagatctctgcc tacaggatcctgcttttccagatttcagaagatgtgaacaaagtggaattgaaggacttt aagttttttttgagccaggagattgccaaatgtaagctggatgatgacatgactttgctt gatatttttgtggagatggagaagaggaccatcctaggggaaaataacttggacaccctg aaaagaatctgcgagcaggtcaacaagagcttgctgaagaaaatctatgattatgaagaa ttaagaaaagattcagagagaagaatgagacttgaaagagatccagatgaattttcaaat gatatgtcacaatcgcttccagaggagggctcctctgagctgctggccatagcagactct ctagcagaactggacagtgagttgcagacatccgacacagtttaccgaatgacaagcaaa cctcggggatactgtttgatctttaacaattatgattttagcatagcacgggagcaggtg cccgaacttcacagccttaaggataggaatggaacacacttggatgcagaggctttggaa aagacctttagtgaacttcattttgagatagtgcactacagagaccaaacagcaaaggga atctgtgaggttctgaaatcttaccagaagaaggaccacagaaccaaagactgcttcatc tgctgcatcctcacccatggaaacaagggcaccatctatggctccgatgggcaagaagcc cccatctatgagctgacctcctacttcactggatcaaaatgcccttcccttgttggcaaa cccaaaatcttttttattcaggcttgtcaaggggataagtaccagagaggtatagctgtt gagaccgactcagaacagatggaagcctatttagaagtggattcatcaccccacaagaga tatattccagatgaggctgactttctgctggggatggccactgtgaataactgtgtttcc taccgaagcatcttgaaggggacctggtatatccaatcactttgccagaacctgagagaa agatgtcctaggggtgaagatattctgaccatcctaaccaaggtgaacttcgaagtaagc aaaaaggatgacaagcaaaatatgggcaaacagatgccacaacctactttcacactgcga aaaaaactcttctttcctcttaattga

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