Otolemur garnettii (small-eared galago): 100951299
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Entry
100951299 CDS
T07855
Symbol
IRS2
Name
(RefSeq) LOW QUALITY PROTEIN: insulin receptor substrate 2
KO
K07187
insulin receptor substrate 2
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga04022
cGMP-PKG signaling pathway
oga04068
FoxO signaling pathway
oga04081
Hormone signaling
oga04140
Autophagy - animal
oga04152
AMPK signaling pathway
oga04211
Longevity regulating pathway
oga04213
Longevity regulating pathway - multiple species
oga04910
Insulin signaling pathway
oga04920
Adipocytokine signaling pathway
oga04923
Regulation of lipolysis in adipocytes
oga04930
Type II diabetes mellitus
oga04931
Insulin resistance
oga04932
Non-alcoholic fatty liver disease
oga04935
Growth hormone synthesis, secretion and action
oga05010
Alzheimer disease
oga05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
100951299 (IRS2)
04022 cGMP-PKG signaling pathway
100951299 (IRS2)
04152 AMPK signaling pathway
100951299 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
100951299 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100951299 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100951299 (IRS2)
04923 Regulation of lipolysis in adipocytes
100951299 (IRS2)
04920 Adipocytokine signaling pathway
100951299 (IRS2)
04935 Growth hormone synthesis, secretion and action
100951299 (IRS2)
09149 Aging
04211 Longevity regulating pathway
100951299 (IRS2)
04213 Longevity regulating pathway - multiple species
100951299 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
100951299 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
100951299 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100951299 (IRS2)
04932 Non-alcoholic fatty liver disease
100951299 (IRS2)
04931 Insulin resistance
100951299 (IRS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Motif
Other DBs
NCBI-GeneID:
100951299
NCBI-ProteinID:
XP_023374960
LinkDB
All DBs
Position
Unknown
AA seq
1496 aa
AA seq
DB search
MASPPLHGLPGPASGDGPNLNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGSDEAT
ATAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKD
EYFAVAAENEQEQEGWYRALTDLVSEGRASAGDAPPASSATSGSCSASLPGALGGSAGAA
GADDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSV
TLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELF
EFRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSS
CRVRTASEGDGGAAVGTGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXAHSPPAATSPGSLSSSSGHGSGSYPLPPGAHPHLPHPL
HHPTSQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSDTPESIAETPPARDG
SGGALCGYMTMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSAS
LDEYTLMRATFSGSSGRLCPSCPASSPKVTYHPYPEDYGDIEIGSHRSSSSNLGADDGYM
PMTPGVALMGSGGGSCKSDDYMPMSPTSVSAPKQILQPRAATAALPPSGAVVPAPTSAAN
RTFPGNGVSYKTSSPAESSPEDSGYMRMWCGSKLSVENADSKLLPNGDYLNMSPSDAGTA
GTPPDFFSAALHGGADTLKGVPGYCYSSLPRSYKAPYACGGGSDQYVLMSAPVGRILEEE
RVEPQATPGTAQAAGTFGASGSGHTQPHHPVVPSTVRPSGSGRPDGFLSQRCRAVRPTRL
SLEGLQTLPSMHEYPLPSEPKSPGEYINIDFGEAGARLSPPAPPLLTSAASSCSLLSASS
PASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGTQSADPVGSLDALLSPEASSP
YPPLPPRPAASPSSLQQPPPPPPPGELYRLPATSAAATAQGPRAASSSSSETGDNGDYTE
MAFGVAATPPQPIAAPPKLEGTRVTSPTSGLKRLSLMDQVSGVEAFLQAGQPPDPHRGAK
VIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGSGGVLG
GGPGGGDEPPTSPRQLQPSVQPPSLPPQARPWAPGQPGGLVGCPGGSGSPMRRETSTGFQ
NGLNYIAIDVRDESGLAQPQPGDKSSWGRTRSLGGLISTVSGGGGCGGPGPGGLPSTGTY
ASIDFLPHHLTEATVVKDIHDLSRKVPFPSCAEEASLPPAPPSAHGAASHPENSSAPAPC
RLLRWPGQLEKGDPTWLGSSVSPAHQAEVGVLQSEDGSGRVPLTSHIPDVIKGRGSAFFS
LKLLTVAFGCERFPCCETSVGRCQTWSRRAGRPPPRSFCAASALCCLRLFCSVLFF
NT seq
4491 nt
NT seq
+upstream
nt +downstream
nt
atggccagcccgccgctgcacgggctccccgggccggcgagcggagacggccccaatctc
aacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcagaag
cacggccacaagcgcttcttcgttctgcgcgggcccggcgcgggcagcgacgaggcgaca
gcgacggcgggcggggggtcggcgccgcagccgccgcggctcgagtactacgagagcgag
aagaagtggcggagcaaggcgggcgccccgaagcgggtgatcgcgctagactgctgcctg
aacatcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaaggac
gagtacttcgcggtggcagcagagaacgagcaggagcaggagggctggtaccgcgcgctc
accgacttggtcagcgagggccgcgccagcgccggcgacgcgccccccgcctcctcggcc
acctctgggtcctgcagcgcctccctgccgggcgccctgggcggctcggccggcgccgct
ggggccgatgacagctacgggctagtggcgcccgccacggccgcctaccgcgaggtgtgg
caggtgaacctgaagcccaagggtctgggccagagcaagaacctgacgggcgtgtaccgc
ctgtgcctgtccgcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtg
acgctgcagctcatgaacatccgccgctgcggccactcggacagcttctttttcatcgag
gtgggccgctcggctgtcaccggccccggagagctgtggatgcaggcggacgactcggtg
gtggcgcagaacatccacgagaccatcctggaggccatgaaggcgctcaaggagctcttc
gagttccggccgcgcagtaagagccagtcgtcggggtcgtcggccacgcacccgataagt
gtccccggcgcgcgccgccaccaccacctggtcaacctaccccccagtcagacaggcctg
gtacgccgctcgcgcaccgacagtctggccgccacccccccggccgccaagtgcagctca
tgccgagtgcgcacagccagcgagggcgacggcggcgcggcggtggggaccggggnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnggcgcactcgccgccagccgccaccagccccggcagcctgtcttccagcagcggg
cacggctcgggctcctaccctctgcctccgggcgcccacccgcacctgccgcaccccttg
caccaccccacgagccagcggccctccagcggcagcgcctcagcctctggctcccccagc
gacccgggcttcatgtccctggacgagtacggctccagccctggcgacctaagagccttc
tgtagccacaggagcgacacgcctgagtccatcgcggagacgcctccggcccgggacggc
agcgggggcgcgctgtgcggctacatgaccatggacaggcccctgagccactgtggccgt
ccctaccgcagagtctctggcgacggggcccaggacttggacagagggctgaggaaaagg
acttactccctgaccacacctgcccggcagcggccggtgccccagccctcctcagcctcc
ctggacgaatacaccctgatgcgggccaccttctcgggcagctccggccgcctgtgcccg
tcgtgcccagcgtcttctcccaaagtgacttaccacccctacccggaggattacggggac
attgagattgggtcccacaggagctccagcagtaatctgggggcagacgacggttacatg
cccatgacccccggcgtggccctcatgggcagtggcgggggcagctgcaagagtgacgat
tacatgcccatgagccccaccagcgtgtccgcccccaagcagatccttcagcctagggcg
gccacggctgccttgcccccctcaggagccgtggtgccagcgcccacctctgccgccaac
aggacctttccagggaatggggtcagttacaagaccagctcccccgcggagagctccccc
gaggacagtgggtacatgcggatgtggtgtggctccaaactgtccgtcgaaaatgctgac
agcaagctgcttcccaatggggactacctcaacatgtcccccagcgacgcgggcactgcc
ggtaccccacccgacttcttctctgcagccttgcacggcggggcggacacgctcaaaggc
gtgcccggctactgctacagctccctgccgcgctcctacaaggccccttacgcctgcgga
gggggcagcgaccagtatgtgctcatgagcgcccctgtggggcggatcttggaagaggag
agggtggagccacaggccaccccagggacggctcaggcggcgggcaccttcggggccagt
gggagtggccacactcagccgcatcaccccgtagtgccttccaccgtgaggcccagtggc
agcggccgccccgacggcttcctgagccagcgctgtcgggccgtgcggcccacgaggctg
tccctggagggtctgcagacgctgcccagcatgcacgaataccctctgccgtcagagccc
aagagcccaggcgagtacatcaacattgactttggcgaggcgggagcccgcctgtcgccg
cctgcccctccgctgctgacgtcggcagcctcatcctgctcgctgttgtccgccagcagc
ccggcctcgtccctgggctcgggcacgccgggcaccagcagtgacagccggcagcgctct
ccgctctccgactatatgaacctcgacttcagctcacctaagtcgcccaagccgggcacc
cagagcgcagaccccgtgggctctttggacgccctcctctcccccgaggcctcctcacct
tacccaccgctgcccccacgccctgcagcatcgccatcctcactgcagcagccgccaccc
ccgccgcccccaggggagctgtaccgcctgcccgcaacttcggccgcggccactgcccag
ggcccccgagctgcgtcgtcgtcgtcctctgagactggggacaatggtgactacaccgag
atggcctttggtgtggctgccaccccaccacaacccattgcagcgcccccaaagctggaa
ggtacccgagtgaccagcccgacatctggcctcaagagactgagtcttatggatcaagtg
tcgggggtcgaggccttcctgcaggccggccagcctccagacccacaccggggcgccaag
gtcatccgcgcggacccacagggcggtcgccgccgccacagctcggagaccttctcctcg
actacaaccgtcaccccagtgtctccatcctttgcccacaaccccaagcgccacaactcg
gcctctgtggaaaacgtgtctctcaggaaaagcagtgaaggcagtggtggcgtccttggt
gggggcccaggtgggggcgacgagccgcccacatcccccagacagctgcagccttccgtc
cagccgccctccctcccacctcaggcccggccttgggccccaggccagcctgggggcttg
gtgggctgccctgggggcagtggttctccaatgcgcagagagacctctaccggcttccag
aatggtctcaactacatcgccattgacgtgagggacgagtcgggactggcccagccacag
cctggagacaagagttcctggggccggacccgtagccttgggggtctcatcagcaccgtg
agcggtggcggcgggtgtgggggcccgggtcctggcggcctgccctctaccggcacctac
gccagcattgatttcttgccccatcacttgacggaggccaccgtggtgaaagacatccat
gacctatccaggaaagtccccttcccttcctgtgcagaggaggcttccctgccaccagca
ccccccagtgctcacggtgctgcctcccaccctgagaacagctctgctcctgccccctgc
cggctgctgcggtggccagggcagttggagaagggagatcccacttggctgggcagctct
gtgtcaccagcccatcaggctgaggtgggagtcttgcagagtgaagatgggtcgggccgc
gtccccctgacgtcacacatcccagatgtcattaaaggaagaggctcagcgtttttttca
ctgaagctgctcacggttgcttttggatgtgagcgattcccgtgttgtgagacctccgtg
ggccgttgtcagacatggagccgccgggcaggccgcccgcctccccgctccttctgtgcg
gcctccgcattgtgctgtttgcgtttgttctgttctgttttgtttttctaa
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