Otolemur garnettii (small-eared galago): 100955860
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Entry
100955860 CDS
T07855
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X2
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga04014
Ras signaling pathway
oga04072
Phospholipase D signaling pathway
oga04148
Efferocytosis
oga04360
Axon guidance
oga04625
C-type lectin receptor signaling pathway
oga04630
JAK-STAT signaling pathway
oga04650
Natural killer cell mediated cytotoxicity
oga04660
T cell receptor signaling pathway
oga04670
Leukocyte transendothelial migration
oga04722
Neurotrophin signaling pathway
oga04920
Adipocytokine signaling pathway
oga04931
Insulin resistance
oga05168
Herpes simplex virus 1 infection
oga05205
Proteoglycans in cancer
oga05208
Chemical carcinogenesis - reactive oxygen species
oga05211
Renal cell carcinoma
oga05220
Chronic myeloid leukemia
oga05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100955860 (PTPN11)
04630 JAK-STAT signaling pathway
100955860 (PTPN11)
04072 Phospholipase D signaling pathway
100955860 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100955860 (PTPN11)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100955860 (PTPN11)
04660 T cell receptor signaling pathway
100955860 (PTPN11)
04670 Leukocyte transendothelial migration
100955860 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
100955860 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
100955860 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100955860 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
100955860 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100955860 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
100955860 (PTPN11)
05211 Renal cell carcinoma
100955860 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100955860 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
oga01009
]
100955860 (PTPN11)
Enzymes [BR:
oga01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
100955860 (PTPN11)
Protein phosphatases and associated proteins [BR:
oga01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
100955860 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
PTPlike_phytase
Y_phosphatase3
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
100955860
NCBI-ProteinID:
XP_003790014
Ensembl:
ENSOGAG00000000348
LinkDB
All DBs
Position
Unknown
AA seq
593 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF
RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR
EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH
EYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDNARVYENVGLMQQQKSFR
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaatatcactggcgtggaggcagaaaacctactg
ttgacaagaggagttgatggcagttttttggcaaggcccagtaaaagtaaccctggagac
tttacactttctgttagaagaaatggagctgtcactcacatcaagatccagaacactggt
gattactatgacctgtatggtggggagaagtttgccaccttggctgagttggtccagtat
tacatggaacatcatgggcaattaaaagagaagaatggagatgttattgagctcaaatat
cctctgaattgtgcagatcctacctctgaaaggtggtttcatggacacctctctgggaaa
gaagcagagaaattactaactgaaaaaggaaagcatggtagctttcttgtacgagagagc
cagagtcaccccggagattttgttctctctgtgcgcactggtgatgacaaaggggagagc
aatgacggcaaatctaaagtgacccatgtcatgattcgctgtcaggaactaaaatacgat
gttggtggaggagagcggttcgattctttaacagatcttgtggaacattacaagaagaat
cctatggtagaaactttgggtacagtactgcaactcaagcagcccctcaacacaactcgt
attaatgctgctgaaatagaaagcagggttcgagaactaagcaaattggctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagacactacaacaacaggagtgtaaa
cttctctacagccgtaaagaaggtcaaaggcaagaaaataaaaacaaaaatagatataaa
aacattctgccctttgatcataccagagttgtcctccatgacggtgatcccaatgagcct
gtttcagattacatcaacgcaaatattatcatgcccgaatttgaaaccaagtgcaacaat
tcaaagcccaaaaagagttatatcgccacacaaggctgcctgcaaaacacggtgaatgac
ttttggcggatggtattccaagagaattcccgagtgattgtcatgacaacaaaagaagtg
gagaggggaaagagtaaatgtgtcaaatactggcctgatgaatatgccctaaaggaatat
ggggtcatgcgcgttaggaatgtcaaagaaagtgctgctcatgactatacattaagagaa
cttaaactttcgaaggttggacaagggaatacggagagaacggtctggcaataccacttt
cggacctggccggaccatggagtgcccagtgaccctggcggtgtgctggacttcttggag
gaggtccaccacaagcaggagagcatcatggacgcagggccggtggtggtgcactgcagt
gctggaattggccggactgggactttcatcgtgattgatatccttattgacatcatcaga
gagaaaggtgttgactgtgacattgacgttccaaaaaccatccagatggtgcgatctcaa
aggtcaggaatggtccagacagaagcacagtaccgatttatctatatggccgtccagcat
tatattgaaacactacagcgcaggattgaagaagagcagaaaagcaagaggaaagggcac
gaatatacaaatattaagtattctctagcggatcagaccagtggagatcagagccccctc
ccgccttgtaccccaacgccgccctgtgcagaaatgagggaagataatgctagagtctat
gaaaacgtgggcctgatgcagcagcagaaaagcttcagatga
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