Otolemur garnettii (small-eared galago): 100956072
Help
Entry
100956072 CDS
T07855
Symbol
MAP2K2
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 2 isoform X2
KO
K04369
mitogen-activated protein kinase kinase 2 [EC:
2.7.12.2
]
Organism
oga
Otolemur garnettii (small-eared galago)
Pathway
oga01521
EGFR tyrosine kinase inhibitor resistance
oga01522
Endocrine resistance
oga04010
MAPK signaling pathway
oga04012
ErbB signaling pathway
oga04014
Ras signaling pathway
oga04015
Rap1 signaling pathway
oga04022
cGMP-PKG signaling pathway
oga04024
cAMP signaling pathway
oga04066
HIF-1 signaling pathway
oga04068
FoxO signaling pathway
oga04071
Sphingolipid signaling pathway
oga04072
Phospholipase D signaling pathway
oga04140
Autophagy - animal
oga04148
Efferocytosis
oga04150
mTOR signaling pathway
oga04151
PI3K-Akt signaling pathway
oga04210
Apoptosis
oga04218
Cellular senescence
oga04270
Vascular smooth muscle contraction
oga04370
VEGF signaling pathway
oga04371
Apelin signaling pathway
oga04540
Gap junction
oga04550
Signaling pathways regulating pluripotency of stem cells
oga04613
Neutrophil extracellular trap formation
oga04620
Toll-like receptor signaling pathway
oga04650
Natural killer cell mediated cytotoxicity
oga04660
T cell receptor signaling pathway
oga04662
B cell receptor signaling pathway
oga04664
Fc epsilon RI signaling pathway
oga04720
Long-term potentiation
oga04722
Neurotrophin signaling pathway
oga04730
Long-term depression
oga04810
Regulation of actin cytoskeleton
oga04910
Insulin signaling pathway
oga04912
GnRH signaling pathway
oga04915
Estrogen signaling pathway
oga04916
Melanogenesis
oga04917
Prolactin signaling pathway
oga04919
Thyroid hormone signaling pathway
oga04921
Oxytocin signaling pathway
oga04926
Relaxin signaling pathway
oga04929
GnRH secretion
oga04934
Cushing syndrome
oga04935
Growth hormone synthesis, secretion and action
oga05010
Alzheimer disease
oga05022
Pathways of neurodegeneration - multiple diseases
oga05132
Salmonella infection
oga05135
Yersinia infection
oga05160
Hepatitis C
oga05161
Hepatitis B
oga05163
Human cytomegalovirus infection
oga05164
Influenza A
oga05165
Human papillomavirus infection
oga05166
Human T-cell leukemia virus 1 infection
oga05167
Kaposi sarcoma-associated herpesvirus infection
oga05170
Human immunodeficiency virus 1 infection
oga05200
Pathways in cancer
oga05205
Proteoglycans in cancer
oga05206
MicroRNAs in cancer
oga05207
Chemical carcinogenesis - receptor activation
oga05208
Chemical carcinogenesis - reactive oxygen species
oga05210
Colorectal cancer
oga05211
Renal cell carcinoma
oga05213
Endometrial cancer
oga05214
Glioma
oga05215
Prostate cancer
oga05216
Thyroid cancer
oga05218
Melanoma
oga05219
Bladder cancer
oga05220
Chronic myeloid leukemia
oga05221
Acute myeloid leukemia
oga05223
Non-small cell lung cancer
oga05224
Breast cancer
oga05225
Hepatocellular carcinoma
oga05226
Gastric cancer
oga05230
Central carbon metabolism in cancer
oga05231
Choline metabolism in cancer
oga05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
oga00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100956072 (MAP2K2)
04012 ErbB signaling pathway
100956072 (MAP2K2)
04014 Ras signaling pathway
100956072 (MAP2K2)
04015 Rap1 signaling pathway
100956072 (MAP2K2)
04370 VEGF signaling pathway
100956072 (MAP2K2)
04371 Apelin signaling pathway
100956072 (MAP2K2)
04066 HIF-1 signaling pathway
100956072 (MAP2K2)
04068 FoxO signaling pathway
100956072 (MAP2K2)
04072 Phospholipase D signaling pathway
100956072 (MAP2K2)
04071 Sphingolipid signaling pathway
100956072 (MAP2K2)
04024 cAMP signaling pathway
100956072 (MAP2K2)
04022 cGMP-PKG signaling pathway
100956072 (MAP2K2)
04151 PI3K-Akt signaling pathway
100956072 (MAP2K2)
04150 mTOR signaling pathway
100956072 (MAP2K2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100956072 (MAP2K2)
04148 Efferocytosis
100956072 (MAP2K2)
09143 Cell growth and death
04210 Apoptosis
100956072 (MAP2K2)
04218 Cellular senescence
100956072 (MAP2K2)
09144 Cellular community - eukaryotes
04540 Gap junction
100956072 (MAP2K2)
04550 Signaling pathways regulating pluripotency of stem cells
100956072 (MAP2K2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100956072 (MAP2K2)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
100956072 (MAP2K2)
04620 Toll-like receptor signaling pathway
100956072 (MAP2K2)
04650 Natural killer cell mediated cytotoxicity
100956072 (MAP2K2)
04660 T cell receptor signaling pathway
100956072 (MAP2K2)
04662 B cell receptor signaling pathway
100956072 (MAP2K2)
04664 Fc epsilon RI signaling pathway
100956072 (MAP2K2)
09152 Endocrine system
04910 Insulin signaling pathway
100956072 (MAP2K2)
04929 GnRH secretion
100956072 (MAP2K2)
04912 GnRH signaling pathway
100956072 (MAP2K2)
04915 Estrogen signaling pathway
100956072 (MAP2K2)
04917 Prolactin signaling pathway
100956072 (MAP2K2)
04921 Oxytocin signaling pathway
100956072 (MAP2K2)
04926 Relaxin signaling pathway
100956072 (MAP2K2)
04935 Growth hormone synthesis, secretion and action
100956072 (MAP2K2)
04919 Thyroid hormone signaling pathway
100956072 (MAP2K2)
04916 Melanogenesis
100956072 (MAP2K2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100956072 (MAP2K2)
09156 Nervous system
04720 Long-term potentiation
100956072 (MAP2K2)
04730 Long-term depression
100956072 (MAP2K2)
04722 Neurotrophin signaling pathway
100956072 (MAP2K2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100956072 (MAP2K2)
05206 MicroRNAs in cancer
100956072 (MAP2K2)
05205 Proteoglycans in cancer
100956072 (MAP2K2)
05207 Chemical carcinogenesis - receptor activation
100956072 (MAP2K2)
05208 Chemical carcinogenesis - reactive oxygen species
100956072 (MAP2K2)
05230 Central carbon metabolism in cancer
100956072 (MAP2K2)
05231 Choline metabolism in cancer
100956072 (MAP2K2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100956072 (MAP2K2)
09162 Cancer: specific types
05210 Colorectal cancer
100956072 (MAP2K2)
05225 Hepatocellular carcinoma
100956072 (MAP2K2)
05226 Gastric cancer
100956072 (MAP2K2)
05214 Glioma
100956072 (MAP2K2)
05216 Thyroid cancer
100956072 (MAP2K2)
05221 Acute myeloid leukemia
100956072 (MAP2K2)
05220 Chronic myeloid leukemia
100956072 (MAP2K2)
05218 Melanoma
100956072 (MAP2K2)
05211 Renal cell carcinoma
100956072 (MAP2K2)
05219 Bladder cancer
100956072 (MAP2K2)
05215 Prostate cancer
100956072 (MAP2K2)
05213 Endometrial cancer
100956072 (MAP2K2)
05224 Breast cancer
100956072 (MAP2K2)
05223 Non-small cell lung cancer
100956072 (MAP2K2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100956072 (MAP2K2)
05170 Human immunodeficiency virus 1 infection
100956072 (MAP2K2)
05161 Hepatitis B
100956072 (MAP2K2)
05160 Hepatitis C
100956072 (MAP2K2)
05164 Influenza A
100956072 (MAP2K2)
05163 Human cytomegalovirus infection
100956072 (MAP2K2)
05167 Kaposi sarcoma-associated herpesvirus infection
100956072 (MAP2K2)
05165 Human papillomavirus infection
100956072 (MAP2K2)
09171 Infectious disease: bacterial
05132 Salmonella infection
100956072 (MAP2K2)
05135 Yersinia infection
100956072 (MAP2K2)
09164 Neurodegenerative disease
05010 Alzheimer disease
100956072 (MAP2K2)
05022 Pathways of neurodegeneration - multiple diseases
100956072 (MAP2K2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100956072 (MAP2K2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100956072 (MAP2K2)
01522 Endocrine resistance
100956072 (MAP2K2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oga01001
]
100956072 (MAP2K2)
Enzymes [BR:
oga01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.2 mitogen-activated protein kinase kinase
100956072 (MAP2K2)
Protein kinases [BR:
oga01001
]
Serine/threonine kinases: STE group
STE7 family
100956072 (MAP2K2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
Haspin_kinase
CAMSAP_CC1
Seadorna_VP7
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
100956072
NCBI-ProteinID:
XP_003788798
Ensembl:
ENSOGAG00000001658
UniProt:
H0WJ32
LinkDB
All DBs
Position
Unknown
AA seq
400 aa
AA seq
DB search
MLARRKPVLPALTINPAIAEGPSPTSEGASETNLVDLQKKLEELELDEQQKKRLEAFLTQ
KAKVGELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQ
VLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRG
LAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQ
GTHYSVQSDIWSMGLSLVELSIGRYPIPPPDAKELEALFGRAVADGLEGEAHSISPRPRP
PGRPISGPGLDSRPAMAIFELLDYIVNEPPPKLPNSVFTPDFQEFVNKCLIKNPAERADL
KILMNHAFIKRSEVEEVDFAGWLCKTLRLNQPSTPTRTAV
NT seq
1203 nt
NT seq
+upstream
nt +downstream
nt
atgctggcccggaggaagccggtgctgccggcgcttaccatcaaccccgccatagccgag
ggcccgtctcccaccagcgagggcgcctccgaaacaaatctagtggacctccaaaagaag
ctcgaggagctagaactcgacgagcaacaaaagaagcgactagaagccttcctcacccag
aaggccaaggttggcgagctcaaggatgatgactttgaaaggatctcagagctgggtgcg
ggcaatggtggggtggtcaccaaagtccagcacagaccttcaggcctcatcatggccaga
aagctgatccacctggagatcaagccagccatccggaaccaaatcattcgagagctgcag
gttctgcacgagtgcaattcaccatacatcgtcggcttctacggggccttctacagtgat
ggggagatcagcatctgcatggagcacatggatggtggctccctggaccaggtgctgaaa
gaagccaagaggattcctgaggagatcctggggaaagtcagcattgcagtcctccggggc
ttggcgtacctacgagaaaagcaccagatcatgcacagagatgtgaaaccctccaacatc
ctcgtcaactccagaggggagataaagctgtgtgatttcggggtgagcgggcagctcatc
gactccatggccaactcctttgtaggaactcgatcctacatgtctccagagcggttgcaa
ggcacacactactcggtgcagtctgacatctggagcatgggcctgtcgctggtggagctg
tccattggaaggtaccccatccccccacccgacgccaaggagctggaggccctatttggc
cgggccgtggccgatgggctggaaggagaggcccacagcatctcgcctcggccgagacca
cctgggcgccctatcagtggtcctgggctggacagtcggccagctatggccatcttcgag
ctactggattacattgtgaatgagcctcctcccaagctgcccaacagcgtgttcacccca
gacttccaggagtttgtaaataaatgcctcatcaagaaccctgcagagcgcgcagacctg
aagatactcatgaaccacgccttcatcaaacggtccgaggtggaagaggtggattttgct
ggctggttgtgtaaaacgctgcggttgaaccagcccagtacacccacacgcacagctgtg
tga
DBGET
integrated database retrieval system
