KEGG   Otolemur garnettii (small-eared galago): 100960589
Entry
100960589         CDS       T07855                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
oga  Otolemur garnettii (small-eared galago)
Pathway
oga01522  Endocrine resistance
oga04110  Cell cycle
oga04115  p53 signaling pathway
oga04151  PI3K-Akt signaling pathway
oga04218  Cellular senescence
oga04530  Tight junction
oga04660  T cell receptor signaling pathway
oga04933  AGE-RAGE signaling pathway in diabetic complications
oga04934  Cushing syndrome
oga05160  Hepatitis C
oga05162  Measles
oga05163  Human cytomegalovirus infection
oga05164  Influenza A
oga05165  Human papillomavirus infection
oga05166  Human T-cell leukemia virus 1 infection
oga05167  Kaposi sarcoma-associated herpesvirus infection
oga05169  Epstein-Barr virus infection
oga05200  Pathways in cancer
oga05203  Viral carcinogenesis
oga05212  Pancreatic cancer
oga05214  Glioma
oga05218  Melanoma
oga05219  Bladder cancer
oga05220  Chronic myeloid leukemia
oga05222  Small cell lung cancer
oga05223  Non-small cell lung cancer
oga05224  Breast cancer
oga05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:oga00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    100960589 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    100960589 (CDK4)
   04115 p53 signaling pathway
    100960589 (CDK4)
   04218 Cellular senescence
    100960589 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    100960589 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    100960589 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100960589 (CDK4)
   05203 Viral carcinogenesis
    100960589 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    100960589 (CDK4)
   05225 Hepatocellular carcinoma
    100960589 (CDK4)
   05214 Glioma
    100960589 (CDK4)
   05220 Chronic myeloid leukemia
    100960589 (CDK4)
   05218 Melanoma
    100960589 (CDK4)
   05219 Bladder cancer
    100960589 (CDK4)
   05224 Breast cancer
    100960589 (CDK4)
   05222 Small cell lung cancer
    100960589 (CDK4)
   05223 Non-small cell lung cancer
    100960589 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100960589 (CDK4)
   05160 Hepatitis C
    100960589 (CDK4)
   05164 Influenza A
    100960589 (CDK4)
   05162 Measles
    100960589 (CDK4)
   05163 Human cytomegalovirus infection
    100960589 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100960589 (CDK4)
   05169 Epstein-Barr virus infection
    100960589 (CDK4)
   05165 Human papillomavirus infection
    100960589 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100960589 (CDK4)
   04934 Cushing syndrome
    100960589 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100960589 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oga01001]
    100960589 (CDK4)
Enzymes [BR:oga01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     100960589 (CDK4)
Protein kinases [BR:oga01001]
 Serine/threonine kinases: CMGC group
  CDK family
   100960589 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 100960589
NCBI-ProteinID: XP_003790635
Ensembl: ENSOGAG00000014371
LinkDB
Position
Unknown
AA seq 305 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFPPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLQKDEG
NPSEQ
NT seq 918 nt   +upstreamnt  +downstreamnt
atggctacctctcggtatgagccagtggctgaaattggtgtcggtgcctatgggacagtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtaagagtgccc
aatggaggaggagctggagggggccttcccatcagcacagttcgagaggtggccttacta
aggcggctggaggcttttgagcaccccaatgttgttcggctcatggacgtctgtgccaca
tcccgaactgaccgggagattaaagtcaccctggtgtttgagcatgtagaccaagaccta
agaacttatctggacaaggcacccccaccaggcttgccagctgagaccatcaaggatctg
atgcgacaatttctaagaggccttgatttcctgcatgctaattgcattgttcatcgagat
ctgaagccagagaatattctggtgacaagtggtgggacagtcaagctggctgactttggc
ctggctagaatctacagctaccagatggcacttacacctgtggttgttaccctctggtac
cgagctccagaagttctcttgcagtctacatatgcaacacctgtggacatgtggagcgtt
ggctgtatttttgcagagatgtttcgtcgaaagcctctcttctgtggaaactctgaagct
gaccagttgggcaaaatctttgacctgatagggctgcctccagaggatgactggcccagg
gatgtctctctaccccgaggagcctttcctccaagagggccccgcccagtgcagtcagtg
gtgcctgagctggaggagtctggagcacagctgctgctggaaatgctgacttttaaccca
cacaagcgaatttctgccttccgagctctgcagcattcttatcttcagaaggatgaaggt
aatccaagtgagcaatag

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