KEGG   Otolemur garnettii (small-eared galago): 111727809
Entry
111727809         CDS       T07855                                 
Name
(RefSeq) E3 ubiquitin-protein ligase Mdm2
  KO
K06643  E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
Organism
oga  Otolemur garnettii (small-eared galago)
Pathway
oga01522  Endocrine resistance
oga01524  Platinum drug resistance
oga04068  FoxO signaling pathway
oga04110  Cell cycle
oga04115  p53 signaling pathway
oga04120  Ubiquitin mediated proteolysis
oga04144  Endocytosis
oga04151  PI3K-Akt signaling pathway
oga04218  Cellular senescence
oga04625  C-type lectin receptor signaling pathway
oga04919  Thyroid hormone signaling pathway
oga05163  Human cytomegalovirus infection
oga05165  Human papillomavirus infection
oga05169  Epstein-Barr virus infection
oga05200  Pathways in cancer
oga05202  Transcriptional misregulation in cancer
oga05203  Viral carcinogenesis
oga05205  Proteoglycans in cancer
oga05206  MicroRNAs in cancer
oga05214  Glioma
oga05215  Prostate cancer
oga05218  Melanoma
oga05219  Bladder cancer
oga05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:oga00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    111727809
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    111727809
   04151 PI3K-Akt signaling pathway
    111727809
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    111727809
  09143 Cell growth and death
   04110 Cell cycle
    111727809
   04115 p53 signaling pathway
    111727809
   04218 Cellular senescence
    111727809
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    111727809
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    111727809
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    111727809
   05202 Transcriptional misregulation in cancer
    111727809
   05206 MicroRNAs in cancer
    111727809
   05205 Proteoglycans in cancer
    111727809
   05203 Viral carcinogenesis
    111727809
  09162 Cancer: specific types
   05214 Glioma
    111727809
   05220 Chronic myeloid leukemia
    111727809
   05218 Melanoma
    111727809
   05219 Bladder cancer
    111727809
   05215 Prostate cancer
    111727809
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    111727809
   05169 Epstein-Barr virus infection
    111727809
   05165 Human papillomavirus infection
    111727809
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    111727809
   01522 Endocrine resistance
    111727809
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oga04131]
    111727809
   04121 Ubiquitin system [BR:oga04121]
    111727809
Enzymes [BR:oga01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     111727809
Membrane trafficking [BR:oga04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    111727809
Ubiquitin system [BR:oga04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   MDM2/MDM4 proteins
    111727809
SSDB
Motif
Pfam: zf-C3HC4_3 Zn_ribbon_RanBP zf-RING_2 zf-FPG_IleRS
Other DBs
NCBI-GeneID: 111727809
NCBI-ProteinID: XP_023373698
LinkDB
Position
Unknown
AA seq 279 aa
ILTQCFFFLQDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDED
DEVYRVTVYQAEESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWTLRENWLPE
DKGKDRRDISEKAKLENSAQAEEGFDVPDCKKTTGSDSKESSVEVNDDKITQASQSQDSE
DYSQPSTSNSIIYSSQEDVKEFEREETQDKEESLESSFPLSAIEPCVICQGRPKNGCIVH
GKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
NT seq 840 nt   +upstreamnt  +downstreamnt
atattgacacagtgttttttctttcttcaggatcttgatgctggtgtaagtgaacattca
ggtgactggttggatcaggattcagtttcagatcagtttagtgtagaatttgaagttgaa
tctcttgattcggaagattatagtcttagtgaagaaggacaagaactctcagatgaagat
gatgaggtgtatcgagttactgtgtatcaagcagaggagagtgatacagattcatttgaa
gaagatcctgaaatttctctagctgactattggaaatgtacttcatgcaatgaaatgaat
cctcctcttccatcacattgcaacagatgttggacccttcgtgagaattggcttcctgaa
gataaaggaaaagacagaagggatatctctgagaaagccaaactagaaaactcagcacaa
gccgaagagggctttgatgttccggattgtaaaaaaactacagggagtgattccaaagag
tcatctgtggaggtaaatgatgataaaatcactcaggcctcccagtcacaagacagtgag
gactattctcagccatcaacttccaatagcattatttacagcagccaagaagatgtcaaa
gagtttgagagggaggaaacccaagacaaagaagagagtttggagtccagctttcccctt
agtgccattgaaccttgtgtgatttgccaaggtcgacctaaaaatggttgcattgtccat
ggcaaaacaggacatcttatggcatgcttcacgtgtgcaaagaagctgaagaagaggaat
aagccctgcccagtgtgcagacagccaatccagatgatcgtgctaacgtacttcccctag

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