KEGG   Oreochromis niloticus (Nile tilapia): 100711065
Entry
100711065         CDS       T06104                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
  KO
K01116  phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
onl  Oreochromis niloticus (Nile tilapia)
Pathway
onl00562  Inositol phosphate metabolism
onl01100  Metabolic pathways
onl04012  ErbB signaling pathway
onl04020  Calcium signaling pathway
onl04070  Phosphatidylinositol signaling system
onl04370  VEGF signaling pathway
Module
onl_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:onl00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100711065
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100711065
   04370 VEGF signaling pathway
    100711065
   04020 Calcium signaling pathway
    100711065
   04070 Phosphatidylinositol signaling system
    100711065
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:onl04131]
    100711065
Enzymes [BR:onl01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100711065
Membrane trafficking [BR:onl04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    100711065
 Endocytosis
  Macropinocytosis
   Phospholipase C
    100711065
SSDB
Motif
Pfam: PI-PLC-X SH2 PI-PLC-Y EF-hand_PLCG2 C2 PH SH3_1 EF-hand_PLCG1 SH3_9 PH_12 SH2_1 SH3_2 EF-hand_6 EF-hand_9 GDPD EF-hand_7
Other DBs
NCBI-GeneID: 100711065
NCBI-ProteinID: XP_005468317
Ensembl: ENSONIG00000019477
LinkDB
Position
LG17:25475460..25516957
AA seq 1312 aa
MCAARFSGCLNGCADEAPSSVAGAAGSVMVSRMLDWSEAGARILHSLEMGTVMTIFYQKK
SQRPERRTFQIRQDTRQIVWSRNPDKIEGEIDIREIRELRLGKGSRDFERYPEEARKLDS
THCFIVLYGLEFRLRTLSVAAFSEEEVNMWITGLNWLMMDTQRAPAPQQIDRWLRKQFEV
MDRSHEGSITVKDVKALLPQVNYRVPNMRFLKDKLQEVEARSDLSYPNFAQLYRTLMFDA
QRSITEQLELSFPLRNVDRPELCQISLYDFQKFLQMDQKESWASDLGRVREFLMGYMRGA
PQPEPMLQLDEFLTFLYSKENSVCDPRLSPVVPDDMKRPLSQYWISSSHNTYLTGDQFSS
ESSLEAYARCLRMGCRCIELDCWDGPDDLPIIYHGHTLTSKIKFLDVLHTIKEHAFVTSE
YPVILSIEDHCSVVQQRNMATHFKKVFGDLLLTKPVDNNAEELPSPYQLRRKILIKHKKL
VEGTLYEEVTSASYSENDISNSLKNGILYLEDPIDHTWTPHYFVLTSNKIYYSEETSHYQ
TADEEEDDEGKEECNNNEQHCAERWFHGKLGGGRDGRQVAEKLLQEYCEGGAKDGTFLVR
ESETFVGDYTLSFWRSGRVQHCRIHSRQESGSTRFYLTDNLVFDSLYRLICHYRDTPLRC
NEFEMRLGNPVPQPNAHESREWYHSNLSRVQAEHMLMRVPRDGAFLVRKRSEHNSYAISF
RAEGKIKHCRIQQEGRLFMLGSSAEFESLVDLVSYYEKHPLYRKMRLRYPINEDTLDRMG
TTELDYGALYEVRTPHFYVEANKMPTARCTVKALYDYRAQREDELCFPKQALILNVDKQE
GGWWRGDYGGKKQLWFPANYVEEVPSSPTREMDEASTENSPLGTFLKGFIDVPTCHVVVH
KDGKNSRAFVFTIHSQHLSSHPVQTLDVAADSLEDLTGWVSKIREAAQNADARMQEEKQM
ERRKKIAVELSDLVVYCRPVPFNEDKIGTERACYRDMSSFPETKAEKFATRGRGKRFLQY
NRRQLSRIYPRGQRLDSSNYDPLPMWLCGSQLVALNFQTPDKPMQLNQALFMLGGGSGYV
PQPDIMRDDTFDPFDKDTLHVEPITIQLQVLGARHLPKNGRSIVCPFVELEICGADYDSY
KCKTDVVADNGLNPVWVQKQFVFDIHNPTFAFLRFTVYEEDMFSDPNFLAQATYPVRLLK
TGYRSVPLKNSYSEELELASLLVHIEIVNAKEEDDENLYTSIQRLRDRTSELSNQVSLLE
RSGSADLSYQQSLEELRATQDQLSELVEARNRRLMEKKRREKLRQQVIAKRS
NT seq 3939 nt   +upstreamnt  +downstreamnt
atgtgtgcagccagattcagtggctgcctcaatggctgtgctgacgaggcccccagtagt
gttgcaggggctgctggttcagtcatggtctccaggatgctggactggtctgaggcaggt
gcccgcatcctccacagcctggaaatgggcacagtgatgaccatcttctatcagaaaaag
tctcagcgccctgagaggagaacgttccagataaggcaggacacgaggcagatagtgtgg
agcagaaacccagacaaaatagaaggagagatcgacatacgggagatccgggagctgcgg
ttggggaagggctcccgtgattttgagcgctacccagaggaggctcgtaagctggactcc
acccactgctttatagtgctgtacggcctggagtttcgcctccggaccctcagtgtagct
gccttcagtgaggaggaagtcaacatgtggatcactggactcaactggctaatgatggac
acgcagagggcaccggcaccacaacagattgacaggtggctgaggaaacagtttgaagtc
atggacaggagccatgagggcagcattacagtgaaggatgtgaaagctctgctgcctcag
gtcaactaccgagtgcccaacatgcgctttctcaaagacaagctacaggaggtggaggcc
aggagcgacctgtcataccccaactttgcacagctctacagaacactgatgtttgatgca
cagaggagtattactgagcagctggagctctccttccctctgcgaaatgttgacagacca
gagctttgtcaaatctccctctatgactttcaaaagtttttacagatggaccagaaggag
tcctgggcatcagatctgggtcgtgtcagggagtttcttatgggctacatgaggggggca
ccacagcctgagccgatgctacaactggatgagttcctgaccttcctgtactctaaagag
aattctgtgtgtgaccctcgtctttcacccgtagttcctgatgacatgaaaaggccattg
tctcagtactggatctcatcttcgcacaacacgtacctgacaggtgaccagttttccagt
gaatcatctctagaagcctacgctcgctgtctgaggatgggctgccgctgcattgaactg
gactgctgggatggacctgatgacctgccaatcatctaccacggccacaccttaacttcc
aagatcaaattcctggatgtgctgcataccatcaaagaacatgcctttgttacatctgag
tatcctgtgatcttatccatcgaggaccactgcagtgtggtccagcagaggaacatggcc
acgcacttcaagaaagtttttggagatctgctgctcaccaaaccggttgacaataacgca
gaggagcttccttcgccctaccagctccgcaggaagatcctcatcaaacacaagaagctg
gtggaaggaaccctgtatgaagaggtgacgtcagccagctactctgaaaacgacatcagt
aactccctaaagaacggcatcctttacctcgaagaccccattgaccatacatggacgcca
cattattttgtcctgaccagtaataagatttactactctgaggagacatctcattatcag
acagctgatgaagaggaggatgatgaaggaaaggaggagtgcaacaacaatgagcagcac
tgtgcagagcgctggtttcatgggaagctgggtggaggacgcgatggccgtcaggtggct
gagaaactcctgcaggagtactgcgagggcggggccaaagacggcaccttcctggtccgg
gagagtgagacgtttgttggagactacaccctctccttctggcgctctggtcgggtccag
cactgcaggatccattcacgtcaggagtctggctccacccgcttctacctgactgataac
ctggtgtttgacagcctctaccggctcatctgccactatagagacacgccgctccgctgc
aacgagtttgagatgaggctgggaaaccctgtacctcagccgaatgcacacgaaagcaga
gagtggtaccactccaacctgtcccgtgttcaggctgaacacatgctgatgcgtgtgccc
agagacggagctttcctggttcgaaaacgtagcgaacacaactcctacgccatctccttc
agggcagagggtaagatcaaacactgccgtatccagcaagaaggccgtctcttcatgttg
ggtagctcggcagagtttgagagtctggtggatctggtgagctactatgagaaacatcct
ctgtatcgtaaaatgaggctccgctaccccatcaatgaagatactctagaccggatgggc
accacggagcttgactatggcgcactgtatgaggttcgcactcctcatttctatgtggag
gctaataagatgcccacagcacggtgtacggtcaaagctctgtatgactatcgagctcag
agagaagacgagctatgtttccccaaacaagcactcatcctgaatgtggataagcaggag
ggcggctggtggagaggtgactatggaggaaagaagcagctgtggttccctgcaaactat
gtagaggaggtccctagttcccccaccagagaaatggatgaagcatccacagagaacagt
cctctgggaactttcctcaaaggcttcatagatgtaccaacctgccacgtggtggtgcat
aaagacggaaagaattcccgggcctttgtgttcactatccactcccaacacctctcttct
catccggtccagactctggacgtagcagctgacagtctggaagatctcaccggctgggtc
agcaagattagagaggctgcacagaatgctgatgcacgaatgcaggaggagaaacagatg
gagaggaggaagaagattgcagtggagctgtcggacctcgtggtctactgcagacctgtc
cccttcaatgaggacaagattgggacggagcgagcatgttaccgggatatgtcctccttc
ccggagacgaaggcagagaagtttgcgacccgtggccgagggaaacgctttctgcagtac
aaccgtcgtcagctttccaggatttatcccagaggacagaggctggactcctccaactat
gaccctctacctatgtggctctgtggctcccagctggttgcactcaatttccagacccca
gataaacccatgcagctgaaccaagctttgttcatgctcggaggtggcagcggctatgtt
ccccagcctgacatcatgagggatgacacgtttgaccctttcgacaaggacacattgcac
gtggagccaatcaccatccaattacaggtgctgggtgctcgccatctgcctaagaatggc
cggagcattgtctgtccctttgtagagttggaaatctgtggagccgactatgacagctac
aagtgcaagacagatgttgtagctgataatggtctgaaccctgtgtgggtgcagaagcag
tttgtgttcgatatccacaaccccaccttcgcctttctgcgcttcaccgtctacgaggag
gacatgttcagcgatcccaacttcctggcacaggcaacctacccagtccgtctgctcaaa
acaggctacaggagtgtacctctaaaaaacagctacagtgaggagctcgagctagcgtcc
cttctggttcacatagaaatcgtcaatgcaaaggaggaagacgatgagaacttgtacacg
tccatccagcggttgcgagatcgaaccagcgagctgtccaaccaggtttctctcctggag
aggtcgggctcagcagacctgagctatcagcaaagtctggaggagctccgagccactcag
gaccagctgagtgagctggtggaggctcgcaaccgcaggctgatggagaagaagagaagg
gagaagctgagacaacaggtgatagcaaagcgcagctaa

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