Orcinus orca (killer whale): 101269506
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Entry
101269506 CDS
T05247
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein isoform X9
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor01524
Platinum drug resistance
oor03440
Homologous recombination
oor03460
Fanconi anemia pathway
oor04120
Ubiquitin mediated proteolysis
oor04151
PI3K-Akt signaling pathway
oor05206
MicroRNAs in cancer
oor05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101269506 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
101269506 (BRCA1)
03460 Fanconi anemia pathway
101269506 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
101269506 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101269506 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
101269506 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101269506 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
oor01009
]
101269506 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
oor04121
]
101269506 (BRCA1)
03036 Chromosome and associated proteins [BR:
oor03036
]
101269506 (BRCA1)
03400 DNA repair and recombination proteins [BR:
oor03400
]
101269506 (BRCA1)
Enzymes [BR:
oor01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
101269506 (BRCA1)
Protein phosphatases and associated proteins [BR:
oor01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
101269506 (BRCA1)
Ubiquitin system [BR:
oor04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
101269506 (BRCA1)
Multi subunit type E3
BRCC complex
101269506 (BRCA1)
Chromosome and associated proteins [BR:
oor03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
101269506 (BRCA1)
DNA repair and recombination proteins [BR:
oor03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
101269506 (BRCA1)
BRCA1-A complex
101269506 (BRCA1)
BRCA1-B complex
101269506 (BRCA1)
BRCA1-C complex
101269506 (BRCA1)
BRCA complex
101269506 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
101269506 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-RING_2
zf-C3HC4_3
zf-RING_5
BRCT_2
RING_XB3-XBAT31
zf-RING_6
zf-Nse
zf-RING_10
zf-ANAPC11
zf-rbx1
Prok-RING_4
RTT107_BRCT_5
zf-RING_4
Motif
Other DBs
NCBI-GeneID:
101269506
NCBI-ProteinID:
XP_004282903
LinkDB
All DBs
Position
19:40210862..40274151
Genome browser
AA seq
765 aa
AA seq
DB search
MDFSANHVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
CPLCKNHITKRSLQESTRFSQLVEELLKIIHAFELDTGLQVANSYNFSKKENNSSEHLKE
EVSIIQSMGYRNRAKKLQQSEPENPTLQETSLSVQLSNLGIVRSLRTKQQIQPQNKSVYI
ELGSDSSEDTVNKASYFSVGDHELLEITPQGAKAEASLNRAKKAACEFSEKDITKAEHHQ
FSNKDLTTTEKHETEKHPEKYQGEAASEYESETSLSEDCLGLSSQSDILTTQQRDTMQDN
LLKIQQEMAELEAVLEQHGSQPSHSSPSLIADSCASEDLLNLEQNTSEKVLTSEKSSEYP
ISQNPESLSADKFQVSPDTSTSKNKEPGMERSSPSKSQLSDNSWYMHSHSRSLQSRNCPP
QKELEVVDVEEQQMTESEAQDLMEQSSLPRQDLEGTPYLESGISLFSDDPESDPSEDRAP
EPAHVCSMPPSASALKLPQFQAEESARSPAAAHTTNTAGYNVREESVSREKPELIPSTQR
GNKRISMVASGLTPKEFVLVHKFARKHHITLTNLITEETTHVIMKTDAEFVCERTLKYFL
GIAGGKWVVSYFWVTQSIKERKMLDEHDFEVRGDVVNGRNHQGPKRARESQDRKIFKGLE
ICCYGPFTNMPTDQLEWMVHLCGASVVKEPSSFTLSQGTQPVVVVQPDAWTEGGGFHVIG
QMCEAPVVTREWVLDSVALYQCQELDTYLIPQVPRAAADSSLPCI
NT seq
2298 nt
NT seq
+upstream
nt +downstream
nt
atggatttttctgcgaatcacgttgaagaagtacaaaatgtccttaatgctatgcagaaa
atcttagagtgtccaatctgtctggagttgatcaaagagcctgtttccacaaagtgtgat
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacag
tgtcctttgtgtaagaatcatataaccaaaagaagcctacaagaaagtacaagatttagt
cagcttgttgaagagctattgaagatcattcatgcttttgagcttgacacaggattgcag
gttgcaaacagttataacttttcaaaaaaggaaaataactcttctgagcatctaaaggag
gaagtttctatcattcaaagtatgggctaccgaaaccgggccaaaaaacttcaacagagt
gaacctgaaaatcctaccttgcaggaaaccagtcttagtgtccagctctctaaccttgga
attgtgagatctctgaggacaaagcagcagatacaacctcagaataagtccgtctacatt
gaattgggatctgattcttctgaagatacagttaataaggccagttatttcagtgtagga
gaccatgaattgttagaaatcacccctcaaggagccaaggctgaagccagtttgaatcgt
gcaaaaaaggctgcttgtgagttttctgagaaggacataacaaaggctgaacatcatcaa
ttcagtaataaagatttgaccaccactgagaagcatgaaactgagaagcatccagaaaag
tatcagggtgaagcagcatctgagtatgagagtgaaacaagcctctctgaagactgtttg
gggctgtcctctcagagcgatatcttaaccactcagcagagggataccatgcaagataac
ctgctaaagatccagcaggaaatggccgaactggaagctgtgttagagcagcacgggagc
cagccttctcacagctccccttccctcatagccgattcttgtgcctctgaggacctgcta
aatctggaacaaaacacatcagaaaaagtattaacttcagagaaaagtagtgaatatcct
ataagccagaatccagaaagcctttctgctgacaagtttcaagtatctccggatacttcc
accagtaaaaataaagaaccaggaatggaaaggtcttccccttctaaatcgcagttgtca
gataatagttggtatatgcacagccactcaaggagtcttcagagcagaaactgcccacct
caaaaggagcttgaggttgttgatgtggaggagcaacagatgacggagtctgaggcccag
gatttaatggagcagtcttctttgccaagacaagatctagagggaaccccttacctagaa
tctggaatcagcctcttctctgatgaccctgagtctgatccctctgaagacagagcccca
gagccagctcatgtctgcagcatgccaccctcagcctctgcactgaaattaccccaattt
caagcagaagaatctgccaggagtccggctgcagctcatactactaatactgcagggtat
aatgtgagggaagaaagtgtgagcagggagaagccagagttgataccttcaacacaaaga
ggcaacaaaagaatttctatggtggcatcaggcttgaccccaaaagaatttgtgcttgtg
cacaagtttgccagaaaacatcacatcactttaactaatctaattactgaagagactact
catgtcattatgaaaacagatgctgagtttgtgtgtgaacggacactgaaatattttctg
ggaattgcaggaggaaaatgggtagttagctatttctgggtgacccagtctattaaagaa
agaaagatgctggatgagcatgattttgaagtcagaggcgatgttgtcaatggaagaaac
catcaaggcccaaagcgagcaagagaatcccaggacaggaagatcttcaagggcttagaa
atctgttgctatggaccgtttaccaatatgcccacagatcaactagagtggatggtgcat
ctgtgtggggcttctgtggtgaaggagccctcatcattcaccctcagccagggtactcaa
ccagttgtggtcgtgcagccagatgcctggacagagggcggtggcttccatgtcatcggg
cagatgtgtgaagcacctgtggtgacccgagagtgggtattggacagcgtagccctctac
cagtgccaggagctggacacctacctgataccccaggtccccagagctgctgctgattcc
agcctgccatgtatatag
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