Orcinus orca (killer whale): 101271458 Help Entry 101271458         CDS       T05247                                  Symbol HK1 Name (RefSeq) hexokinase-1 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism oor  Orcinus orca (killer whale) Pathway oor00010   Glycolysis / Gluconeogenesis oor00051   Fructose and mannose metabolism oor00052   Galactose metabolism oor00500   Starch and sucrose metabolism oor00520   Amino sugar and nucleotide sugar metabolism oor00524   Neomycin, kanamycin and gentamicin biosynthesis oor01100   Metabolic pathways oor01200   Carbon metabolism oor01250   Biosynthesis of nucleotide sugars oor04066   HIF-1 signaling pathway oor04910   Insulin signaling pathway oor04930   Type II diabetes mellitus oor04973   Carbohydrate digestion and absorption oor05230   Central carbon metabolism in cancer Module oor_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate oor_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc oor_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:oor00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     101271458 (HK1)    00051 Fructose and mannose metabolism     101271458 (HK1)    00052 Galactose metabolism     101271458 (HK1)    00500 Starch and sucrose metabolism     101271458 (HK1)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     101271458 (HK1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     101271458 (HK1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     101271458 (HK1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101271458 (HK1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     101271458 (HK1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     101271458 (HK1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     101271458 (HK1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:oor04131]     101271458 (HK1) Enzymes [BR:oor01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      101271458 (HK1) Membrane trafficking [BR:oor04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     101271458 (HK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 FGGY_N UvrD-helicase Motif Other DBs NCBI-GeneID:  101271458 NCBI-ProteinID:  XP_004280841 LinkDB All DBs Position 14:27803576..27887239 Genome browser AA seq 993 aa AA seqDB search MGAEEVGRLEAVTLAGTGARRLGAREPPPRPRSWGRSGRRRRRRSRGAAARGPLLTQAAE DRRPPQACRPASPTASMIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLLDIMARFK KEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILLVQVNHEQKQT VHMESEVYDTPESIMHGSGSQLFGHVAECLGDFMEKKKIKDKKLPVGFTFSFPCRQSKID EAILITWTKRFKASGVEGTDVVKLLEKAIKKHGDYDANVVAVVNDTVGTMMTCGYDDQQC EVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDREIDRG SLNPGKQLFEKMVSGMYMGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEK NKEGLHNAREILTRLGVEPSDDDCISVQHVCTIVSFRSANLVAATLGAILNRLRDNKSTP RLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDCDVRFLLSESGSGKGAAMVTAVAYRLA EQHRQIEETLAHFSLTKDTLLEVKRRMRAEMELGLGKQTHDKAVVKMLPSFVRSTPDGTE HGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPTEIMQGTGEELFDHIVSCISD FLDYMGIKGPRMPLGFTFSFPCKQTSLDAGILITWTKGFKATDCVGQDVATLLRDAVKRR EEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVETLEGNEGQMC INMEWGAFGDNGCLDDIRTIYDKLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKR GFLFRGQISEPLKTRGIFQTKYLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCG VVSKRAAQLCGAGMAAVVDKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSP KCNVSFLLSEDGSGKGAALITAVGVRLRQETSS NT seq 2982 nt NT seq  +upstreamnt  +downstreamnt atgggcgccgaggaggtgggccggctggaggctgtcaccctcgcggggacgggagcgcgg agactgggagcgcgcgagccgccgccgcgccccaggtcgtgggggaggagcggccggagg aggaggaggaggagccgcggagctgcagcccggggaccactgctcacccaggctgcggag gacagacgcccgccccaagcctgccgccccgcgtccccgaccgccagcatgatcgccgcg cagctcctggcttattacttcaccgaactgaaggatgaccaagtcaaaaagatcgacaaa tatctctatgccatgcggctctctgatgaaactctgttagatatcatggctcgtttcaaa aaggagatgaagaatggcctctcccgggattttaatccgacagccacagtcaagatgttg ccaacatttgtaaggtccattcctgatggttcagaaaagggagatttcattgccctggat cttggcgggtcttcctttcgaattctgctggtgcaagtgaatcatgagcaaaaacagacc gttcatatggagtctgaggtttacgacaccccggagagcatcatgcacggcagtggaagc cagctttttggtcatgtcgctgagtgcctgggagacttcatggagaaaaaaaaaatcaag gacaagaaattacctgtgggattcacgttttctttcccttgtcggcaatccaaaatagac gaggccatcctgatcacctggacaaagagatttaaagcgagtggagtggagggaacggat gtggtgaagctgcttgagaaagccatcaaaaagcacggggactatgacgccaacgttgtg gctgtggtgaacgacactgtggggaccatgatgacctgtggctacgacgaccagcagtgt gaagtcggcctcatcattggcacgggcaccaacgcgtgctacatggaggaactgaggcac atcgacctggtggaaggcgacgaagggaggatgtgcatcaacaccgagtggggggccttc ggggacgacggggccctggaggatatccgcaccgagtttgaccgggagattgaccgcggc tcactcaaccccgggaagcagctgtttgagaagatggtcagtggcatgtacatgggcgag ctggtccgattgatcctggtcaagatggccaaggagggccttttatttgaagggcggatc accccggagctgctcaccagagggaagtttaacaccagtgacgtgtcagccattgaaaag aataaggaaggcctccacaacgccagagaaatcctgacccgcctgggagtggagccatct gatgacgactgtatttcggtccagcacgtgtgcaccattgtctcgttccgctctgccaac ctagtggctgcgacgctgggcgccatcctgaatcgtcttcgagataacaagagcacaccc aggctgcggaccacggttggtgtcgacgggtctctttacaagacgcacccacagtattcc cggcgtttccacaagaccctgaggcgcttggtgcccgactgcgatgtgcgtttcctcctc tcggagagtggcagcggcaagggggctgccatggtgactgcggtggcctaccgcctggct gagcagcaccggcagatagaggagaccctggcccacttcagtctcaccaaggatacgctg ctggaggtgaaaaggaggatgcgggccgagatggaattggggctgggcaagcagacgcat gacaaggccgtcgtcaagatgctgccctcctttgtccggagcactcccgatgggacagag cacggtgacttcctggccctggatcttggaggaacgaatttccgcgtcttgctggtgaaa attcgtagtgggaaaaagagaacagtggaaatgcacaacaagatctacgccattcccacg gaaatcatgcagggcactggggaagagctgtttgaccacatcgtttcttgcatctctgac ttcctggactacatgggcatcaagggccccagaatgcctctgggcttcacgttttcgttt ccctgcaagcagacgagcttggatgcgggaatcttgatcacctggacgaaaggttttaag gcaactgattgcgtggggcaggatgtagcgaccttactgagggatgcggtaaaaaggaga gaggaatttgacttggacgtggtggctgtggtcaatgacacggtgggcaccatgatgacc tgtgcttatgaggagcccacctgcgaggttggactcatcgtagggacgggcagcaatgcc tgctacatggaagaaatgaaaaacgtcgagacgctagaaggaaacgagggccaaatgtgt atcaacatggagtggggtgcctttggggacaacgggtgtctggatgatatcagaacgatc tatgacaaactggtggatgaatattctctaaacgctgggaagcaaaggtatgagaagatg atcagcggtatgtacctgggtgaaatcgtccgcaacatcttgatagatttcaccaagagg ggattcctcttccgagggcagatctctgagccgctgaagactcggggcatctttcagacc aagtatctctctcagatcgagagcgaccgattagcgctgctgcaggtccgggccatcctc cagcagcttggcctgaacagcacatgcgacgacagcatccttgtgaagaccgtgtgcggg gtagtgtccaagagggccgcacagctgtgtggcgcaggcatggctgccgtggtggacaag atccgcgagaacagggggctggaccacctcaacgtgactgtgggcgtggacgggacgctc tacaagcttcatccgcatttctccagaatcatgcaccaaaccgtgaaggaactgtcacca aagtgtaacgtgtccttcctcttatccgaagacggtagcggcaagggagccgccctcatc acggcagtgggcgttcggctccggcaagaaacgagcagctaa

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