Orcinus orca (killer whale): 101273673
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Entry
101273673 CDS
T05247
Symbol
IKBKE
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X4
KO
K07211
inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:
2.7.11.10
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor04620
Toll-like receptor signaling pathway
oor04621
NOD-like receptor signaling pathway
oor04622
RIG-I-like receptor signaling pathway
oor04623
Cytosolic DNA-sensing pathway
oor04625
C-type lectin receptor signaling pathway
oor04657
IL-17 signaling pathway
oor04936
Alcoholic liver disease
oor05160
Hepatitis C
oor05161
Hepatitis B
oor05162
Measles
oor05164
Influenza A
oor05165
Human papillomavirus infection
oor05167
Kaposi sarcoma-associated herpesvirus infection
oor05168
Herpes simplex virus 1 infection
oor05169
Epstein-Barr virus infection
oor05171
Coronavirus disease - COVID-19
oor05207
Chemical carcinogenesis - receptor activation
oor05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
101273673 (IKBKE)
04621 NOD-like receptor signaling pathway
101273673 (IKBKE)
04622 RIG-I-like receptor signaling pathway
101273673 (IKBKE)
04623 Cytosolic DNA-sensing pathway
101273673 (IKBKE)
04625 C-type lectin receptor signaling pathway
101273673 (IKBKE)
04657 IL-17 signaling pathway
101273673 (IKBKE)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
101273673 (IKBKE)
09172 Infectious disease: viral
05161 Hepatitis B
101273673 (IKBKE)
05160 Hepatitis C
101273673 (IKBKE)
05171 Coronavirus disease - COVID-19
101273673 (IKBKE)
05164 Influenza A
101273673 (IKBKE)
05162 Measles
101273673 (IKBKE)
05168 Herpes simplex virus 1 infection
101273673 (IKBKE)
05167 Kaposi sarcoma-associated herpesvirus infection
101273673 (IKBKE)
05169 Epstein-Barr virus infection
101273673 (IKBKE)
05165 Human papillomavirus infection
101273673 (IKBKE)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101273673 (IKBKE)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101273673 (IKBKE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oor01001
]
101273673 (IKBKE)
Enzymes [BR:
oor01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
101273673 (IKBKE)
Protein kinases [BR:
oor01001
]
Serine/threonine kinases: Other
IKK family [OT]
101273673 (IKBKE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
ABC1
Pkinase_fungal
Kinase-like
RH_dom
WDR62-MABP1_CC
Motif
Other DBs
NCBI-GeneID:
101273673
NCBI-ProteinID:
XP_012393158
LinkDB
All DBs
Position
1:36249823..36272197
Genome browser
AA seq
752 aa
AA seq
DB search
MTTSPESSGGVTQSHKPACPTAEMGRWPASWEQEMQSTVNYLWHTDDLLGQGATASVYKA
RNKKSGELVAVKVFNTASYLRPREVQVREFEVLRKLNHQNIIKLFAVEETGGSRQKVLVM
EYCSSGSLLSVLESPENAFGLSEDEFLVVLRCVVAGMNHLRENGIVHRDIKPGNIMRLVG
EEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYLHPDMYERAVLHKPQQKAFGVAVDLWS
IGVTLYHAATGSLPFVPFGGPRRNKEIMYRITTEKPAGAIAGTQRLENGPLEWSYTLPIT
CQLSMGLQSQLVPILANILEVEQAKCWGFDQFFAETSDILQRVVVHVFSLPQAVVHHVYI
HAHNTIAIFLEAVYKQTNVAPQHQEYLFEGHLCVLEPSVSAQHIAHTTASSPLTLFSMVS
ETPKGLAFRDPALDLPKFVPKVDLQADYNTAKGVLGAGYQALRLAQALLTGQELMLRGLH
WFVEVLQATCRRTLEVTRMALLFLSSSLGTERFSNVAGVPEIQELKRAAELRSKLRTLAE
VLSRCSHNITETKMTLSNLSSELMKNRDQVHADRSIQQIQCCLDKMYLIYKQFKKSRMRP
GLGYNEEQIHKLDKVNFSHLAKRLLQVFQEERVQKYQASLVTHGKRMRVVHETRNHLRLV
GCSVAACNTEAQGAQESLSKILDWLSHQLLQDRTKGAQASPPTTAPYPSPALKDLVLHMQ
ELCKEMKVLASDLQDNNRVIEGLSRVPSAPDI
NT seq
2259 nt
NT seq
+upstream
nt +downstream
nt
atgacaacaagccctgaaagctcggggggcgtcacgcagtcccacaagcctgcatgcccc
acagccgagatgggaaggtggccagccagctgggagcaagagatgcagagcaccgtcaat
tacctgtggcacacggatgacctgctgggtcagggggccactgccagtgtgtacaaggcc
cgaaacaagaaatccggggagctggttgctgtgaaggtcttcaacacggccagctacctg
cgaccccgcgaggtgcaggtgagggagtttgaggtcctgcggaagctgaaccatcagaac
atcatcaagctctttgcggtggaggagacggggggcagccggcagaaggtgctggtgatg
gagtactgctccagcggcagcctgctgagtgtgctggagagccctgagaacgcctttggg
ctgtccgaggacgagttcctggtggtgctgcgctgtgtggtggccggcatgaaccacctg
cgggagaacggcatcgtccaccgagacatcaagcccgggaacatcatgcgcctggtcggg
gaggaggggcagagcatctacaagctgacggactttggggcagcccgggagctggatgac
gacgagaagttcgtctcggtctacggcaccgaggagtacctgcaccctgacatgtatgag
cgggcggtgcttcacaagccccaacagaaagcttttggggtcgccgtggacctctggagc
attggggtgaccctgtaccatgcggccactggcagcctgcccttcgtcccctttggaggg
ccccgacgcaacaaggagatcatgtaccggatcaccacggagaagccagccggggccatt
gcaggcactcagaggctggagaacgggcccctggagtggagctacacactccccatcacc
tgtcagctgtccatggggctgcagagccagctggtgcccatcctggccaacatcctggag
gtggagcaggccaagtgctggggcttcgaccagttctttgcggagaccagtgacatcctg
cagcgagttgtcgtccacgtcttctccttgccgcaggccgtcgtgcaccacgtctacatc
cacgcgcacaacacgatagccatctttctagaggccgtgtacaagcagaccaacgtggcc
ccccagcaccaggagtacctctttgagggtcacctctgtgtcctcgagcccagcgtctca
gcacagcacatcgcccacacgacagcaagcagccccctgaccctgttcagcatggtcagc
gagacccccaaggggctggccttcagggaccctgctctggacctccccaagtttgtcccc
aaagtggacctgcaggcagattacaacacggccaagggtgtgttgggtgccggctaccag
gccctgcggctggcacaggccttgctgacaggacaggagctgatgcttcgggggctgcac
tggttcgtggaggtactccaggccacgtgcaggcggacgctggaggtcacgaggatggcc
ctcctcttcctcagcagcagcctcggcactgagaggttcagcaacgtggctggggtgcct
gagatccaggaactgaagagggccgcagagctgaggtccaagctgcggaccttggctgag
gtcctctccagatgttcccataatatcacagagaccaagatgaccctgagcaacctgagc
tctgagctgatgaagaaccgggatcaggtacatgcggacagaagcatccagcagattcag
tgctgtttggacaagatgtatctcatttacaaacagttcaagaaatccaggatgaggcca
gggcttggctacaacgaggaacagattcacaagctggataaggtgaattttagtcattta
gccaaaaggctcctgcaggtgttccaggaggagcgtgtgcagaagtaccaggcatccctg
gtcacgcatggcaagagaatgagggtggtgcatgagaccaggaaccacctgcgcctggtg
ggctgctccgtggccgcctgtaacacagaagcccagggagcccaggagagcctcagcaag
atccttgactggctatctcaccagctcctgcaggacagaacaaagggggctcaggcctca
ccacccactacagctccttatcctagccctgcactaaaggacctggttctccacatgcaa
gagctctgcaaggagatgaaggtgctggcgtctgacctccaggacaacaaccgcgtcatc
gaagggttaagtagggtcccatcggctcctgacatctga
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