Orcinus orca (killer whale): 101275665
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Entry
101275665 CDS
T05247
Symbol
SHC2
Name
(RefSeq) SHC-transforming protein 2 isoform X1
KO
K17447
SHC-transforming protein 2
Organism
oor
Orcinus orca (killer whale)
Pathway
oor01521
EGFR tyrosine kinase inhibitor resistance
oor01522
Endocrine resistance
oor04012
ErbB signaling pathway
oor04014
Ras signaling pathway
oor04062
Chemokine signaling pathway
oor04072
Phospholipase D signaling pathway
oor04370
VEGF signaling pathway
oor04510
Focal adhesion
oor04650
Natural killer cell mediated cytotoxicity
oor04722
Neurotrophin signaling pathway
oor04910
Insulin signaling pathway
oor04915
Estrogen signaling pathway
oor04917
Prolactin signaling pathway
oor04926
Relaxin signaling pathway
oor04935
Growth hormone synthesis, secretion and action
oor05034
Alcoholism
oor05100
Bacterial invasion of epithelial cells
oor05214
Glioma
oor05220
Chronic myeloid leukemia
oor05224
Breast cancer
oor05225
Hepatocellular carcinoma
oor05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101275665 (SHC2)
04014 Ras signaling pathway
101275665 (SHC2)
04370 VEGF signaling pathway
101275665 (SHC2)
04072 Phospholipase D signaling pathway
101275665 (SHC2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101275665 (SHC2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
101275665 (SHC2)
04062 Chemokine signaling pathway
101275665 (SHC2)
09152 Endocrine system
04910 Insulin signaling pathway
101275665 (SHC2)
04915 Estrogen signaling pathway
101275665 (SHC2)
04917 Prolactin signaling pathway
101275665 (SHC2)
04926 Relaxin signaling pathway
101275665 (SHC2)
04935 Growth hormone synthesis, secretion and action
101275665 (SHC2)
09156 Nervous system
04722 Neurotrophin signaling pathway
101275665 (SHC2)
09160 Human Diseases
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101275665 (SHC2)
05226 Gastric cancer
101275665 (SHC2)
05214 Glioma
101275665 (SHC2)
05220 Chronic myeloid leukemia
101275665 (SHC2)
05224 Breast cancer
101275665 (SHC2)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
101275665 (SHC2)
09165 Substance dependence
05034 Alcoholism
101275665 (SHC2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101275665 (SHC2)
01522 Endocrine resistance
101275665 (SHC2)
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Motif
Pfam:
PID
SH2
DUF7063
Motif
Other DBs
NCBI-GeneID:
101275665
NCBI-ProteinID:
XP_033272614
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Position
3:complement(117353..147177)
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AA seq
585 aa
AA seq
DB search
MTQGPGGRAAPPPPAPPEPEAPTTFCALLPRMPQWKFAAPAGFLGRGPAAARAAGGAGAA
GGAEPEPEPAGSAGVPALAAAVLGACEPRCTAPCPLPALSRCRAAGARGSRGARGAAGPP
DSAADEWIRKGSFIHKPAHGWLHPDARVLGPGVSYIVRYMGCIEVLRSMRSLDFSTRTQL
TREAINRLHEAVPGIRGSWKKKAPNKALASILGKSNLRFAGMSIAVSISIDGLNLSVPAT
HQIIASHHMQSISFASGGDTDMVDYVAYVAKDPINQRACHILECCEGLAQSVISTVGQAF
ELRFKQYLHSPPRVVVPPGRLTGPEDSAWGDEDETEHSYYNRTPGKEPPLGGLVDSRLTP
AQQPCALGALGQGASPARRDARGPQWDVGPSAPPGDGYVQADPRGPRDYEDHLYVNTQGL
DGPETLQPEDSPKKDLFDMRPFEDALRLHECSVAAGPAAAPLPVEDQWPSPPTRRAPIAP
TEEQLRQEPWYHGQMSRRAAEKLLRVDGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDP
EGVVRTKDVLFESISHLIDYHLQNGQPIVAAESELHLRGVVRREP
NT seq
1758 nt
NT seq
+upstream
nt +downstream
nt
atgacgcagggtccgggcgggcgcgcggcccccccgccccccgcacccccggagcctgag
gcgcccaccaccttctgcgcgctgctgccgcgcatgccgcagtggaagttcgcggcccca
gccggcttcctgggccgcggcccggcggcggcgcgggctgcggggggcgcgggggcggcg
gggggagccgagcccgagcccgagccggccggctcggccggcgtcccggcgctggcggcg
gcggtcctgggcgcctgcgagccgcgctgcaccgcgccctgccccctgcctgcgctcagc
cgctgccgggctgccggggcgcgggggtcgcggggcgcgcggggggcagccgggcccccg
gactccgccgccgacgagtggatccgcaaaggcagcttcatccacaagccggcgcacggc
tggctacacccggacgccagggtcctggggcccggggtctcctacatcgttcggtacatg
ggctgcatcgaagtcctccgttccatgcgctccctggacttcagcactcgcacccagctc
accagggaagccatcaaccggctccatgaggccgtgcctggcatccggggctcctggaag
aagaaggcccccaacaaggcactggcctccatcctgggcaagagcaacctgcgcttcgcg
ggcatgagcatcgccgtcagcatctccatcgacggcctcaacctctccgttcccgccacg
caccagatcatcgccagccaccacatgcagtccatctcctttgcgtcggggggtgacacg
gacatggtggattatgtggcctacgtggccaaggaccccatcaaccagagagcctgccac
atcctggagtgctgcgagggcctcgcccagagcgtcatcagcaccgtgggccaagccttc
gagctgcgcttcaaacagtacctgcacagcccccccagggttgtcgtccccccgggaagg
ctgactgggccggaggactcggcctggggggacgaggacgagacagaacacagctactac
aaccgcactcctgggaaggaaccgcccctgggcgggctggtggactccaggctcaccccc
gcgcagcagccctgcgccctcggggcccttggccagggagcatctcctgctcgaagagac
gcccgaggcccgcagtgggacgtgggcccctcagccccgcccggggatggctacgtgcag
gcagacccgcggggcccgcgagactacgaggaccacttgtatgtcaacacgcaaggtctg
gacggcccggagaccctgcagcctgaggacagccccaagaaggacctgttcgacatgaga
cccttcgaggatgccctgaggctgcacgagtgctccgtggccgcgggtccggcggcagcc
ccccttcccgtggaggaccagtggcccagcccgccgacccgccgggcccccatcgccccc
acggaagagcagctgcggcaggagccctggtaccacggccagatgagccgtcgggcggcg
gagaaactgcttcgagtggacggggacttccttgtgcgggacagcgtcaccaacccgggg
cagtatgtcctcaccggcatgcacgcagggcagcccaagcacctgctgctcgtggacccc
gaaggcgtggtgcggacgaaggacgtgctcttcgagagcatcagccacctgatcgactac
cacctgcagaacgggcagcccatcgtggccgccgagagcgagctgcacctgcgtggtgtc
gtcaggcgggaaccctga
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