Orcinus orca (killer whale): 101277470
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Entry
101277470 CDS
T05247
Symbol
FLT1
Name
(RefSeq) vascular endothelial growth factor receptor 1 isoform X1
KO
K05096
FMS-like tyrosine kinase 1 [EC:
2.7.10.1
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor04010
MAPK signaling pathway
oor04014
Ras signaling pathway
oor04015
Rap1 signaling pathway
oor04020
Calcium signaling pathway
oor04066
HIF-1 signaling pathway
oor04151
PI3K-Akt signaling pathway
oor04510
Focal adhesion
oor05202
Transcriptional misregulation in cancer
oor05323
Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101277470 (FLT1)
04014 Ras signaling pathway
101277470 (FLT1)
04015 Rap1 signaling pathway
101277470 (FLT1)
04066 HIF-1 signaling pathway
101277470 (FLT1)
04020 Calcium signaling pathway
101277470 (FLT1)
04151 PI3K-Akt signaling pathway
101277470 (FLT1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101277470 (FLT1)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
101277470 (FLT1)
09163 Immune disease
05323 Rheumatoid arthritis
101277470 (FLT1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oor01001
]
101277470 (FLT1)
Enzymes [BR:
oor01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101277470 (FLT1)
Protein kinases [BR:
oor01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
101277470 (FLT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
I-set
Ig_3
Pkinase
Ig_2
ig
VEGFR-1-like_Ig-like
Ig_VEGFR-1-like_5th
V-set
VEGFR-2_TMD
VEGFR1-3_N_Ig-like
Ig_4
C1-set
Ig_5
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
101277470
NCBI-ProteinID:
XP_004281809
LinkDB
All DBs
Position
18:72809752..72983975
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AA seq
1340 aa
AA seq
DB search
MVSCWDTGALLCALLGGLLLTGCSSGSKLKGPELSLKGTQHVMQAGQTLYLKCRGEGAHS
WSLPATVNKESQSRRLSITQSACGRSGKQFCSTLTLNAAQANHTGFYSCKYLSTPASKKK
KAESTIYIFINDTGRPFLEMHSEIPEIVNMTEGKEVVIPCRVTSPNITVTLKKFPFDTLI
PDGKRITWDSRKGFIISNATYKEIGLLTCETTVNGHEYKTNYLTLRQTNTITDVQISTPS
PVRLLRGHALTLNCTATTPLNTRVQMTWSYPGEINKRASIRQRIDRRNSRNNVFYSILFI
DKVQNRDKGLYVCHVKSGPSLKSVNTSVHIYDKAFITVKPRQQQVFETVAGTRSYRLSVK
VKAFPSPEVVWLKDGLPATEKSARYLVRGYALVIKDVTAEDAGDYTILLGLKQSNVLKNL
TATLIVNVKPQIYEKAVSSFPYPTLYPLGSRQILTCTIYGIPQPTITWFWHPCNHNHSKA
RYDFCSNNEESFILDPDSTVGNRIESITQRTAVLEGKNKTASTLAVADSRISGIYSCMAA
NKVGTVERNINFYITDVPNGFHVNLEKMPTEGEDLKLSCTVNKFLYRDITWILLRTVNNR
TMQHSIRKQKTAVTKEHSVTLHLVIKNASLEDSGTYACRARNMYTGEEILQKKEVTIRDQ
EAPYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILGPGSSTLFI
ERVTEEDEGVYHCKATNQKGSAESSAYLTVQGTSDKSNLELITLTCTCVAATLFWLLLTL
FIRKLKRSSSEMKTDYLSIIVDPDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAF
GKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGAC
TKQGGPLMVIVEYCKHGNLSNYLKSKRALFLLNKDAALHMEPKKEKMEPDLEQGEKQRLD
SVTSSESFASSGFQEDKSLSDAEEEEDSDDFYKQPITMEDLISYSFQVARGMEFLSSRKC
IHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKSYST
KSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKDGMRMRAPEYATPEIYQIMLDCWH
KDPKERPRFAELVEKLGDLLQANVQQDGKDYIPLNAILTGNSGFTYSTPAFSEDFFKEDI
SAPKFNSGSSDNVRYVNAFNFISLEKIKTFEELSPNATSMLDDYQLDSGTLLASPLLKRF
TWAESKPKASLKIDLRVTSTSKESGLSDLSRPAFCHASCGHLSRGRRRFTYDPSELERKI
SCCSPPPDYNSVVPYSTAPV
NT seq
4023 nt
NT seq
+upstream
nt +downstream
nt
atggtcagctgctgggacaccggggccctgctctgcgcgctgctcggcggtctgcttctc
acaggatgtagttcaggttcaaaattaaaaggtcctgagctgagtttaaaaggcacccag
cacgtgatgcaagcaggccagacgctgtatctcaaatgcagaggggaaggggcccattcc
tggtctttgcctgcaacagtgaataaggaaagccaaagccggaggctgagcataacacaa
tctgcctgtggaaggagtggcaagcagttctgcagtactttgactttgaacgcggctcag
gcaaaccacactggcttctacagctgcaaatatctctctacacctgcttccaagaaaaag
aaagcagaatctacaatctacatatttattaatgatacaggtagacctttcttagagatg
cacagtgaaatcccggaaattgtaaatatgaccgaaggaaaggaggtcgtcatcccctgc
cgggttacatcacccaacatcactgttactttaaaaaagtttccatttgatactctgatc
cctgatggaaaaagaataacgtgggacagtaggaagggctttataatatcaaatgcaaca
tacaaagaaatagggcttctgacctgtgaaacaacagtcaacggacacgagtacaagaca
aactatctcacacttcgacaaaccaacacaatcacagacgtccaaatcagcacgccaagc
ccagtcagattacttagaggtcatgctctcaccctcaactgcacggccaccactcccttg
aacacaagagttcagatgacctggagttaccctggggaaataaataagagagcctctata
aggcaacgaattgaccgacgcaattcccgcaacaatgtattctacagcattctttttatt
gacaaagtgcagaacagagacaaaggactttacgtttgtcatgtgaaaagcggcccgtca
ttgaaatctgttaacacctcagtgcatatatatgataaagcgttcatcacagtgaaacct
cgacagcagcaggtgtttgagactgtagctggcacgcggtcttatcggctctctgtgaaa
gtgaaggcgtttccctcgccagaagttgtatggttgaaagatgggttaccagccactgag
aaatctgcccgctacttggttcgtggctatgcgttggtcatcaaagatgtgactgccgaa
gatgcaggggattacacgatcttgctgggcctaaagcagtcaaatgtgttaaaaaacctc
actgccactctaattgtcaatgtgaaaccccagatttatgaaaaggctgtatcatcgttt
ccatacccgactctctacccactgggcagcagacaaatcctgacttgcaccatttacggt
atccctcaacctaccatcacgtggttctggcatccctgtaaccataatcattccaaagca
aggtatgacttttgctccaataatgaagagtcctttatcctggatcctgacagcaccgta
ggaaacagaattgagagcatcactcagcgcacggcagtcttagaaggaaagaataagacg
gctagcaccttggctgtggccgactctagaatttctggaatctacagctgcatggctgcc
aataaagtagggactgtggaaagaaacataaacttttacatcacagatgtgcccaatgga
tttcacgttaacttggaaaaaatgcctacggaaggagaggacctgaaactgtcctgcaca
gttaacaagttcttgtacagagacattacctggatcttgctgcggacagtgaataaccga
accatgcagcacagcatccgcaagcagaaaacggccgtcacgaaagagcactccgtgacg
ctgcacctcgtcatcaagaacgcttccctggaagactcgggcacctatgcctgccgagcc
aggaacatgtacacaggggaagaaatcctccagaagaaagaagtgaccattagagatcag
gaagcaccctacctcctacgaaacctcagtgatcacacagtggctatcagcagttctacg
actttagattgtcacgctaacggtgtcccagagcctcagataacctggtttaaaaacaac
cacaaaatacaacaagaacctggaattattttaggaccaggaagcagcacgctgtttatt
gaaagagtcacggaagaggatgaaggtgtctatcactgcaaagccaccaaccagaagggg
tccgcggagagttcggcatacctcaccgtgcaaggaacctcagacaagtctaatctggag
ctgatcactctgacatgtacctgtgtggctgccaccctcttctggctcctgttaactctc
tttatccgaaaactgaaaaggtcttcttccgagatgaaaactgactacctatcgattatc
gtggacccagatgaagttcccctggatgagcagtgcgaacggctcccttacgatgccagc
aagtgggagtttgcccgggagagacttaaactgggcaaatcacttggaagaggggctttt
ggaaaagtggtccaagcatctgcatttggcattaagaaatcacctacgtgccggacggtg
gctgtaaagatgctgaaagagggggccacggccagtgagtacaaggctctgatgaccgag
ctcaagatcttgacccacatcggccaccacctgaacgtcgtcaacctgctgggagcctgc
accaagcaaggagggcctctgatggtgattgtggaatactgcaaacacggaaatctctcc
aactatctcaagagcaaacgggccttattccttctcaacaaggatgcagccttacacatg
gagcctaagaaagagaaaatggagccagacctggagcagggcgagaaacaaagactagat
agtgttaccagcagcgagagcttcgcaagctccgggtttcaggaggataaaagtctgagt
gatgccgaggaagaggaggattctgacgatttctacaagcagcccatcactatggaagat
ctgatctcttacagttttcaagtggccagaggcatggagtttttgtcttccagaaagtgc
attcatcgggacctggcagcacgaaatatactgctgtctgagaacaacgtggtgaagatt
tgcgattttggccttgcccgggatatttataagaaccccgattacgtgagaaaaggagat
actcgacttcctctgaagtggatggctcccgaatccatctttgacaaaagctacagcact
aagagcgacgtgtggtcttacggagtactgctgtgggagatcttctccttaggtgggtcc
ccatacccgggcgtgcagatggacgaggacttctgcagccgcctgaaggacggcatgagg
atgcgggccccggagtacgccacgcccgaaatctaccagatcatgttggactgctggcac
aaagacccaaaagaaaggccaagattcgcagaacttgtggaaaaactaggcgacttgctt
caagccaacgtacaacaggatggcaaggactatatcccactcaatgccatactgacagga
aatagtgggtttacgtactcaactcctgccttctcagaggacttcttcaaggaagatatt
tctgctccaaagtttaattcaggaagttctgataatgtcagatatgtaaatgctttcaat
ttcatcagcctggaaaaaatcaaaacctttgaagaactttcaccaaatgccacgtccatg
cttgatgactaccagctggacagtggcaccctgctggcctctcccttgctaaagcgcttc
acctgggccgagagtaaacccaaagcctcgctgaagattgacttgagagtaacaagtaca
agtaaggagtcgggcctttctgacctcagcagacccgcgttctgccatgccagctgtggg
cacctcagcagaggccggcgcagattcacctatgacccctcggagctggagaggaagatt
tcgtgctgctctcccccacccgactacaactccgtggtcccgtactccaccgcacccgtc
tag
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