Orcinus orca (killer whale): 101279575 Help Entry 101279575         CDS       T05247                                  Symbol FASN Name (RefSeq) fatty acid synthase   KO K00665   fatty acid synthase, animal type [EC:2.3.1.85] Organism oor  Orcinus orca (killer whale) Pathway oor00061   Fatty acid biosynthesis oor01100   Metabolic pathways oor01212   Fatty acid metabolism oor04152   AMPK signaling pathway oor04910   Insulin signaling pathway oor04936   Alcoholic liver disease Module oor_M00082   Fatty acid biosynthesis, initiation oor_M00083   Fatty acid biosynthesis, elongation Brite KEGG Orthology (KO) [BR:oor00001]  09100 Metabolism   09103 Lipid metabolism    00061 Fatty acid biosynthesis     101279575 (FASN)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     101279575 (FASN)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101279575 (FASN)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     101279575 (FASN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01004 Lipid biosynthesis proteins [BR:oor01004]     101279575 (FASN)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:oor04147]     101279575 (FASN) Enzymes [BR:oor01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.85  fatty-acid synthase system      101279575 (FASN) Lipid biosynthesis proteins [BR:oor01004]  Fatty acid synthase   Animal type    101279575 (FASN) Exosome [BR:oor04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    101279575 (FASN)   Exosomal proteins of breast milk    101279575 (FASN)   Exosomal proteins of colorectal cancer cells    101279575 (FASN)   Exosomal proteins of bladder cancer cells    101279575 (FASN) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Acyl_transf_1 ketoacyl-synt Thioesterase KR Ketoacyl-synt_C KAsynt_C_assoc FAS_pseudo-KR ADH_zinc_N_2 ADH_zinc_N PKS_DH_N PP-binding Methyltransf_12 adh_short Methyltransf_31 DUF7080 PS-DH Methyltransf_23 Methyltransf_11 Thiolase_N ACP_syn_III Motif Other DBs NCBI-GeneID:  101279575 NCBI-ProteinID:  XP_033294694 LinkDB All DBs Position 19:complement(33693592..33712370) Genome browser AA seq 2515 aa AA seqDB search MEEVVIAGMSGKLPESENLEEFWANLIGGVDMVTDDDRRWKAGLYGLPRRLGKLKDLSRF DASFFGVHPKQANTMDPQLRLLLEVTYEAIVDGGINPASLRGTNTGVWVGVSSSEASEAL SRDPETLMGYSMVGCQRAMMANRLSFFFDFKGPSVALDTACSSSLLALQSAYQAIRSGEC PAAVVGGINILLKPNTSVQFMKLGMLSPEGSCKSFDAAGDGYCRAEAVVAVLLTKKSLAR RVYATILNAGTNTDGFKEQGVTFPSGEVQEQLIRSLYESAGLTPESLEYIEAHGTGTKVG DPQELNSIMRALCATRQDPLLIGSTKSNMGHAEPASGLAALIKVLLSLEHGVWAPNLHFH SPNPEIPALQDGRLQVVDRPLPVLGGNVGINSFGFGGSNVHVILRPNAQPPPPPAPHSAL PRLLRASGRTLEAVQGLLEQGLRHSHDLAFVSMLNDIAAAPTATMPFRGYAVLGGQGGNQ EVHQVPAGKRPLWFICSGMGAQWRGMGLSLMRLGSFRDSILRSDEAVKPLGLQVSDLLLS TDEATFDDTVQSFVSLTAIQIALIDLLTSMGLRPDGIIGHSLGEVACGYADGCLSQEEAV LAAYWRAQCIKEANIPPGAMAAVGLSWEECKRRCPPGIVPACHNSKDSVTISGPQAAMSE FVQQLKQEGVFAKEVRTGGIAFHSYFMDSIAPALLQALKKVIREPRPRSAYWLSTSIPEA QWQGHLARTFSAEYNVNNLVSPVLFQEALRHVPEHAVVLEIAPHALLQAILKRGLKSSCT VIPLMKKDHRDNLEFFLGNVGRLHLMGIDINPNGLFPPVEFPAPRGTPLISPHIRWDHSQ TWDVPAMEDFPSGSSCSSATVYKIDASPETPDHYLLDHCIDGRVIFPATGYLFLVWKTLA RALDQNMEQVPVVFEDVTLHQATILPKTGTMPLEVRLLEASCTFEVSENGNLIVSGQIHQ WKDPDPRLFDNQYGTGPTPVDPSAAFHLSQSDVYKELRLRGYNYGPHFQGILEANLEGNT GRLLWKDNWVTFLDTMLQMSLLVPGHRNLCLPTRITAIHIDPTTHRQKLYALQGETQVAD VVVNRYLNSIVAGSVHISRLHASVAPRRQQEQLAPVLEKFCFTPHVESGCLAGSLALQEE LQLCRGLAQALQTKVAQQGLKMVVPGLDSAQAPREAPQQGLPRLLAAACQLQLNGNLQQE LGQVLAQERPLLCDDPLLSGLLDSPALKACVDTALENTASLRMKVVEVLAGDGRLYSRIP ALLNTQPLMQLDYIATDRHPQALEAAQAKLQQLDLTQGQWDPVDPAPSSLSRADLLVCNC ALATLGDPATAVGNMAATLKEGGFLLLHTLLGGYSLGETVAFLTCSESHQGGQHLLSQDE WESLFTGASLHLVALKRSFYGSVLFLCRRPAPQDSPVFLSVEDASFRWVDSLKNILADSS SRPVWLMAVGCTTSGVVGMVNCLRKEPGGHRIRCVLVSNLSSTSPTPEMDPNSLELQKVL QGDLVMNVYRDGAWGAFRHFPLEKDRPEEQTEHAFINILTRGDLSSIRWVCSPLRHAQPT GPGVQLCTIYYASLNFRDIMLATGKLSPDAIPGKWVARDCMLGMEFSGRDARGKRVMGLV PAEGLATSILVSQDFLWDVPSNWTLEEAASVPVVYATAYYALVVRGRMQPGETVLIHSGS GGVGQAAIAIALSLGCCVFTTVGSAEKRAYLQARFPQLNEASFANSRDTSFEQHVLWHTA GKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHPLGMAIFLKNVTFHGILLD AIFDDDSATWQEVSALLQAGIRDGVVQPLKCTVFPKTQVEDAFRYMAQGKHIGKVVLQVR EEEQEAVLQGTKPTLTAALSKTYCPAHKTYIITGGLGGFGLELSQWLMLRGAQKLVLTSR SGIRTGYQARQVREWRRQGVQVLVSTSNASSLDGARSLITEATQLGPVGGVFNLAMVLRD AMLENQTPEFFQDVNKPKYNGTLNLDRVTREACPELDYFVVFSSVSCGRGNASQTNYGFA NSAMERICEKRRHDGLPGLAVQWGAIGDVGVVLETMGTNDIVIGGTLPQRIISCMEVLDL FLNQPHPVLSSFVLAEKKAAAHGDGSSQQDLVKAVAHILGIRDLATVNLDSSLADLGLDS LMAVEVRQTLEREHDRVLSMREIQQLTLRKLQELSSQAGTADELVAPTPKEDSPARQQAQ LNLSTLLVNPEGPTLAPLNSVQSSERPLFLVHPIEGSITVFHSLAAKLSIPTYGLQCTGA APLDSIQSLAAYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAQQSAGPTNNSLFL FDGSHTYVLAYTQSYRAKMTPGCEAEAEAEAMCFFVQQFTDAEHGRVLEALLPLEGLEER VAAAVELIAQSHAGLDRHAVRFAARSFYQKLRAAEKYTPQATYHGNVTLLRAKTGGTYGE DLGADYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESILSIIHSSLAEPRVSVREG NT seq 7548 nt NT seq  +upstreamnt  +downstreamnt atggaggaggtggtgatcgctggcatgtccgggaagctgcctgagtcggagaacttggag gagttctgggccaatctcatcggcggtgtggacatggtgacggatgatgacaggcggtgg aaggcaggactgtatggcctgccccggcggttaggcaagctgaaggacctgtcccggttt gacgcctcgttcttcggggtccaccccaagcaggcaaacacaatggatccccagctgcgc ttgcttctggaggtcacctatgaggccattgtggacggaggcatcaacccagcttccctt cgtgggacgaacaccggtgtctgggtgggtgtgagcagctctgaggcctcagaggctctg agtcgagaccctgagaccctcatgggctacagtatggtgggctgccagcgcgccatgatg gccaaccgcctctccttcttcttcgacttcaaagggcccagcgttgccctggacacagcc tgctcctccagcctgctggccctgcagagcgcctaccaggccatccgcagtggggagtgc cccgcggccgttgtgggtggcatcaacatcctgctgaagcccaacacctcggtgcagttc atgaagttgggcatgctcagccctgagggctcctgcaagtccttcgatgcagcaggggac ggctactgccgtgcagaggctgtggtggccgtcttgctgaccaagaagtccctggcccga cgggtgtatgccaccatcctcaatgccggcaccaacactgatggcttcaaagagcaaggc gtcaccttcccctctggagaggtgcaggagcagctcatccgctccctgtacgagtcggct gggctgacccccgagtccctggagtatatcgaagcccatggcactggcaccaaggtgggc gacccccaggagctgaatagcatcatgcgggccctgtgtgccacccgccaggaccccctg ctgatcgggtccaccaagtcaaacatggggcacgcggagcccgcctccgggctcgcagca ctgatcaaggtgctgctgtccctggaacacggggtctgggcccccaacctgcacttccac agcccgaaccccgagatcccagcgctgcaagacgggcggctgcaggtagtggaccggcct ttgcccgttctcgggggcaatgtgggcatcaactccttcggctttggcggctccaacgtg catgtcatcctccggcccaacgcccagccgcccccgcctcctgccccacactctgccctg ccccgtctgctgcgggccagcgggcgcacccttgaggcggtgcagggcctgctggagcag ggcctccggcacagccatgacctggctttcgtgagcatgctcaacgacatcgcggccgcc cccacggccaccatgcccttccgtggctacgctgtgctgggcggccagggcggcaaccag gaggtgcaccaggtgccggctggcaagcgcccactctggttcatctgctccgggatgggc gcacagtggcgcggcatggggctgagcctcatgcgcctgggcagcttccgcgattccatc ctgcgctcagacgaggccgtgaagcctttgggactgcaggtgtcggacctgttgctgagc acagatgaggccacctttgatgacaccgtccagtccttcgtgagcctcactgccatccag attgccctcatagacctgctgacctccatgggcctgcggcctgacggcatcatcgggcac tccctgggtgaggtggcctgcggctacgctgacggctgcctctctcaggaggaggctgtc ctcgctgcctactggagggcccagtgcatcaaggaggccaacatcccgcctggggccatg gcagctgtgggcttgtcctgggaagagtgtaagcggcgctgcccccctggtatcgtgcct gcctgccacaactccaaggactctgtgaccatctccggacctcaggccgcaatgtccgag ttcgtgcagcagctgaagcaggagggtgtgtttgccaaggaggtgcggacgggtggcata gcgttccactcctacttcatggactccatcgcccctgcgctgctgcaggcactcaagaag gtgatccgggagccacggccccgctccgcgtactggctcagcacctccatccccgaggcc cagtggcagggccacctggcccgcacattctcagctgagtacaacgttaacaacctggtg agccctgtgctgttccaggaggcactgaggcacgtgcccgagcacgccgtggtgctggag atcgccccccatgccctgctgcaggccatcctgaagagaggcctcaagtccagctgcacc gtcatcccgctgatgaagaaggaccacagggacaacctggagttcttcctcggcaacgtg ggcaggctccacctgatgggcattgacatcaaccccaacggtctgttcccacccgtggag ttcccggccccccgggggacccccctcatttccccgcacatcaggtgggaccacagccag acttgggatgtgcccgccatggaggacttccccagcggctcgagctgctcctctgccact gtctataagatcgatgccagccctgagacccctgaccactacctgttggatcactgcatc gacggccgcgtaattttccccgccactggctacctattcctggtctggaagacgctggca cgagccctggaccaaaacatggagcaggtgcctgtggtgttcgaggacgtgacactacac caggccaccatcctgcccaagacagggaccatgcccctggaagtgcggcttctggaggct tcgtgcaccttcgaggtgtctgagaacggcaacctgatcgtgagcgggcagatacaccag tggaaggaccccgatcccaggctctttgacaaccagtatggcacgggccccacacctgta gaccccagtgctgcgttccacctgagccagagcgacgtgtacaaggagctgcggctgcgg ggctacaactacggcccccacttccagggcatcctcgaggccaacctcgaaggtaacaca ggccggctgctgtggaaagacaactgggtgaccttcctggacaccatgctgcagatgtcc ctcctggtcccgggccaccgcaacctgtgcctgcccacacgcatcaccgccatccacatc gaccccaccacccaccggcagaagttgtacgcgctgcaaggcgagacacaagtggccgac gtggtggtgaacaggtatctgaacagcatcgtggccggcagcgtccacatctcgcggctc cacgcctcggtggcccctcggcggcagcaggagcagctggcacccgtcctggagaagttc tgcttcacgccgcatgtggagagcgggtgcctggctgggagcctggccctgcaggaggag ctgcagctgtgcagggggctggcacaggcactgcagacgaaggtggcccagcaggggttg aagatggtggtgcccgggctggacagtgcccaggctccccgggaggccccgcagcagggc ctgcctcggctgctggccgctgcctgccaactgcaactcaatgggaacctacagcaggaa ctgggccaggtcctggcccaggagaggcccctgctgtgtgacgaccccctgctcagcggc ctcctcgactccccagcactgaaggcgtgcgtggacaccgccctggagaacacggccagc ctcagaatgaaggtggtggaggtgctggctggtgacggccgactctattcccgcatcccg gcgctgcttaacacccagcccctgatgcagctggactacatagccactgaccgccacccc caggccctggaggctgcccaagccaagctgcagcagctcgacctgacccaaggccagtgg gaccctgtggacccggcccccagcagcctgagcagggctgacctcctggtgtgcaactgt gccctggccacccttggtgacccggccacggccgttggcaacatggcggctaccctgaag gagggaggcttcctgctgctgcacacgctgctcggaggttactccctgggggagactgtc gcctttctcacctgctctgagtcacatcaaggggggcagcacctcctgagccaggacgag tgggagagcctatttaccggggcatccctgcacctggtggccctgaagaggtccttctac ggctctgtgctcttcctgtgccgccggccagccccgcaggatagcccagtcttcctgtcc gtggaggacgccagcttcagatgggtcgactcactgaagaacatcctggctgactcctcg tcccggcccgtgtggctcatggccgtcggctgcaccacctcaggtgtcgtgggcatggtg aactgtctccgaaaagagcccggcgggcaccggattcggtgcgtcctggtgtccaacctc agtagcacgtcccccacccctgagatggacccaaactccttggagctgcagaaggtgcta cagggggacctggtgatgaacgtctaccgggacggggcctggggggcgttccgccacttc ccactggaaaaggaccggccagaggagcagacagagcatgccttcataaacatcctcacc cgaggggacctctcctccatccgctgggtctgctctcctctgcgccacgcccagcccact ggccctggagtccagctctgcaccatctattatgcctccctcaacttccgagacatcatg ctggccacgggcaagctgtcccctgacgccatcccaggaaaatgggtcgctcgagactgc atgctgggcatggagttctccggccgagatgccagaggcaagcgtgtgatggggctggtg cccgccgaaggcctggccacctccattctggtgtctcaagacttcctgtgggacgtgcct tccaactggaccctggaagaggcagcttcagtgcccgtcgtctatgccacagcctattac gcgttggtagtacgcggacgcatgcagcctggggagacagtgctcatccactcgggctcg ggcggtgtgggtcaggccgccatcgccatcgctctcagcctgggctgctgtgtcttcacc actgtggggtcagctgaaaagcgggcatacctccaggccaggttcccacagctcaacgaa gccagctttgccaactcccgggacacgtccttcgagcagcacgtgctttggcacacggcc gggaagggtgttgacctcgtcctgaattccctggcggaagagaagctgcaggccagcgtg cggtgcctggcccagcatggtcgattcctggaaattggcaaatttgatctttccaacaac catcccctgggcatggccatcttcctgaagaacgtgactttccacgggatcctgctggat gcaatctttgatgacgacagcgccacctggcaggaggtgtcggcgctgctgcaggcgggc atccgggacggtgtggtgcagcccctcaagtgcaccgtgttccccaagacccaggtggag gacgccttccgctacatggcccagggcaaacacatcggcaaagtggtcctccaggtacgc gaggaagagcaggaggcagtgctgcaagggaccaagcccaccctgacggcggccttgtcc aagacctactgcccagcccacaagacctacatcatcacagggggcctgggtggcttcggc ctagagctgtcccagtggctcatgctgcgaggggcccagaagctggtgctgacctcccgc tccgggatccgcacaggctaccaggccaggcaggtccgtgagtggagacgccagggtgtg caggtcctggtgtccaccagcaacgccagctcgctggatggtgcccggagcctcatcact gaggccacccagcttgggcctgtaggcggcgtcttcaacttggccatggtcctgagagac gccatgctggagaaccagacccctgagttcttccaggacgtcaacaaacccaagtacaat ggcaccctgaacttggacagggtgacccgggaggcatgccccgagctggactacttcgtg gtcttctcctcggtgagctgcgggcgtggcaacgccagccagaccaactacgggttcgcc aactccgccatggagcgcatatgtgagaagcgccggcatgacggcctcccaggcctcgcc gtgcagtggggtgcaattggcgatgtgggcgtcgtgctggagaccatgggtaccaacgac atagtcattggcgggacactgccccaacgcatcatctcctgcatggaggtgctggacctc ttcctgaaccagccccaccccgtcctgagcagctttgtgctggcggagaagaaggccgca gcccatggtgacggcagcagccagcaggacctggtgaaggctgtggctcacatcctgggc atccgtgacttggccactgtcaacttggacagctcactggcagacctgggcctagactca ctcatggccgtggaggtgcgccagacgctggagcgagagcatgaccgggtgctgtccatg cgggaaatccagcagctcacgctccggaagctgcaggaactttcctcgcaggctggcaca gctgatgagctggtggcccccacacccaaggaggacagccctgcccggcagcaggcccag ctgaacctgagcaccctgctggtgaaccctgagggcccgaccttggctccactcaactct gtgcagagctccgagcggcccctattcctggtgcaccccatcgagggctccatcacggtg ttccacagcctggctgccaagctcagcattcccacctacggcctgcagtgcacgggagct gcgcccctggacagcatccagagcctggccgcctactacatcgagtgcatcaggcaggtg cagccagaggggccctaccgcatcgctggctactcctatggggcctgcgtggcctttgag atgtgctcacagctgcaggcacagcagagcgccggccccacgaacaatagcctcttcctg ttcgatggctcgcacacctacgtgttggcctacacgcagagctaccgtgccaagatgacc cctggctgcgaggccgaggccgaggccgaggccatgtgcttcttcgtacagcagttcact gacgcggagcacggcagggtgctggaggcgctactgcccctcgagggcctggaggagcgc gtggcagccgccgtggagctgatcgcacagagccatgcgggcctggaccgccatgccgtc cgcttcgcggcgcgctccttctaccagaagctgcgggcggccgagaagtacacgccgcag gccacctaccatggcaacgtgacactgctgcgcgccaagacaggcggcacctacggcgag gacctgggcgccgactacaacctgtcccaggtgtgcgacggcaaggtgtccgtgcacgtc atcgagggtgaccaccgcacgctgctggagggcagcgggctggaatccatcctcagcatc atccacagctccctggccgagccccgggtcagcgtgcgggagggctag

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