Orcinus orca (killer whale): 101282451
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Entry
101282451 CDS
T05247
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor04137
Mitophagy - animal
oor04140
Autophagy - animal
oor04141
Protein processing in endoplasmic reticulum
oor04210
Apoptosis
oor04932
Non-alcoholic fatty liver disease
oor05010
Alzheimer disease
oor05012
Parkinson disease
oor05014
Amyotrophic lateral sclerosis
oor05020
Prion disease
oor05022
Pathways of neurodegeneration - multiple diseases
oor05160
Hepatitis C
oor05162
Measles
oor05168
Herpes simplex virus 1 infection
oor05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101282451 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101282451 (EIF2AK3)
04137 Mitophagy - animal
101282451 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
101282451 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
101282451 (EIF2AK3)
05162 Measles
101282451 (EIF2AK3)
05168 Herpes simplex virus 1 infection
101282451 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
101282451 (EIF2AK3)
05012 Parkinson disease
101282451 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
101282451 (EIF2AK3)
05020 Prion disease
101282451 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
101282451 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101282451 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101282451 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oor01001
]
101282451 (EIF2AK3)
Enzymes [BR:
oor01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101282451 (EIF2AK3)
Protein kinases [BR:
oor01001
]
Serine/threonine kinases: Other
PEK family [OT]
101282451 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
101282451
NCBI-ProteinID:
XP_004285679
LinkDB
All DBs
Position
13:12668370..12736929
Genome browser
AA seq
1122 aa
AA seq
DB search
MERAARPGSLARALLLLLLLLLPPPLQLGLVTGTVAARRASDFPASTVEAAFGLGAAAAP
TSAVRVQAAGAVTAAEVTVEDAEALPAAAGEQEPREPEPDDEADLRPCRRSLVIISTLDG
RIAALDPENHGQKQWDLDVGSGSLVSSSLSKPEVFGNKMIIPSLDGDLFQWDRDRESMET
VPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSAYSGKVRYICSALGCRQWDNDEMEQEE
DILLLQRTQKTVRAVGPRSGSEKWNFSVGHFELRYIPDMETRAGFIESTLKPSGNKEQSK
IISDVEEQEAAVMDTVIKVSVADWKVMAFSKKGGHLEWEYQFCTPIASAWLVKDGKVIPI
SLFDDTSYTTNDGVLEDEEDIVEAARGATENSVYLGMYRGQLYLQSSVRISEKFPTSPKA
LESVNSENAIIPLPTIKWKPLIHSPSRTPVLVGSDEFDKCLSNDKFSHEEYSNGALSILQ
YPYDNGYYLPYYKRERNKRSTQITVRFLDNPNYSKSIRKKDPVLLLHWWKEIVGTILFCI
VATTFIVRRLFHPHPHRQRKESETQCQTENKYDSVSGEANDSSWNDIKNSGYVSRYLTDF
EPIQCMGRGGFGVVFEARNKVDDCNYAIKRIRLPNRELAREKVMREVKALAKLEHPGIVR
YFNAWLEAPPEKWQEKMDEIWLKDESTDWPLTSPSPADAPSVKICRMDPFSTKERVEIIA
PSPRSSRSFSVGISCGQTGSSKSQFSPLEFSGMDHRDTSESVDAVCNLQDSCLTDCKGED
GTRDGNDEGHSFELCPSEASPYVRSRERTSSSIVFEDSGCDNASSKEPKTNRPPIGNHCA
DKLTAVQHSSSKSSSEPTLSISPSRPTTLSLDLTKNSVEKLQPSSPKVYLYIQMQLCRKE
NLKDWLNSRCTIEERERSVCLHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDDVVKVG
DFGLVTAMDQDEEDQLVLTPMPGYARHTGQVGTKLYMSPEQIHGNNYSHKVDIFSLGLIL
FELLYPFGTHMERVRILTDVRDLKFPPLFTQKYPREYVMVQDMLSPSPTERPEAANIIEN
AIFEDLEFPGKTVLRQRSRSMSSSGTKQSRHSSSSHSPLPSN
NT seq
3369 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccgcccgcccggggtcgctggcacgggcgctgctgctgctgctcctgctg
ctgctgccaccaccgctgcagctggggctcgtgacggggacggtggccgcgcggcgcgct
tccgacttccccgcatcgacagtggaggcggcgttcggcctgggggccgcggccgctcca
acttcggccgtgcgggtgcaggcggcgggcgccgtgactgcggcggaggtgacggtggag
gacgccgaggcgctgccggcggccgcgggggagcaggagccgcgggagccggaaccggac
gacgaggccgatcttcggccgtgccgcagatccttagtgattatcagcactttagacggc
cgaattgctgccctggatcctgagaaccatggtcaaaagcagtgggatttggacgtggga
tccggttccttggtgtcgtccagccttagcaaaccggaggtatttgggaataagatgatc
attccttccctggatggagacctcttccagtgggaccgggaccgtgagagcatggaaaca
gttccgtttacagttgaatcgcttcttgaatcttcttataaatttggagatgatgttgtc
ttggttggaggaaagtctctcactacatatggactcagtgcatatagcggaaaggtgagg
tacatctgttcagctttgggctgtcgccaatgggataatgatgaaatggaacaagaagaa
gatatcctgcttctgcagcgcacccagaaaaccgttagagccgtcggccctcgtagtggc
agtgagaagtggaatttcagtgttggccactttgaacttcggtatattccagacatggaa
actagagccggatttattgaaagcaccttaaagcccagtggaaacaaagaacagtctaaa
attatttcagacgtggaagaacaggaagctgccgtgatggacacagtgataaaggtctcc
gttgctgattggaaagttatggcctttagtaagaaaggaggacatctggagtgggaatac
cagttttgtactcccattgcatctgcctggttggttaaggatggcaaagtcattcccatc
agtctttttgatgatacaagttacaccactaatgacggagttttagaggatgaagaagac
atcgtagaagccgcccgaggagccacagaaaacagtgtttacttgggaatgtacagaggc
cagctgtatctgcagtcatcagtcagaatttcagaaaagtttcctacgagtcccaaggcc
ttggaatctgtcaacagtgaaaatgcaattattcctttgccaacaatcaaatggaaaccc
ttaattcattctccttccagaactcctgtcttggtggggtctgatgaatttgacaaatgt
cttagtaatgataagttttctcacgaagagtacagtaatggtgcactttcaatcttgcag
tatccatatgataatggttattacctgccatactacaagagggaaaggaacaaacggagc
acacagatcacagtccgatttctcgacaacccgaattacagcaagagtatccgcaaaaag
gatcccgtgctcctcttacactggtggaaagaaatagttggaaccattctgttttgtatc
gtagcaacaactttcattgtgcgcagactcttccatcctcatcctcacagacaaaggaaa
gaatctgaaactcagtgtcaaactgaaaataaatacgattctgtcagtggagaagcgaat
gacagtagctggaatgacataaaaaattctggatacgtatcacgctatctaacagatttt
gaaccgattcaatgcatgggtcgtggagggtttggagttgtctttgaagctagaaacaaa
gttgatgactgcaattatgctatcaagagaatccgtctcccaaacagggaattggctcgg
gaaaaggtcatgcgagaagttaaagccttagccaagcttgaacacccaggaattgttaga
tatttcaatgcttggttggaagcaccaccagagaagtggcaagaaaaaatggatgaaatt
tggctgaaagatgaaagcacagactggccgctcacctctcctagtcccgcggatgcacca
tccgttaaaatatgcagaatggatcctttctctacaaaggaacgcgttgaaatcatagcc
ccttctccaagaagcagtaggtctttttcggtcgggatttcctgtggccagacaggttca
tccaagagccagttctctccactggaattttccggaatggaccacagagacacgagtgag
tcggtggacgcggtgtgtaacctccaggacagctgccttacagactgcaagggggaagac
ggtactagggatggcaatgatgagggacactcttttgaactttgtccttctgaagcttcc
ccttatgtaaggtcaagggagcgaacctcctcttctatagtatttgaagattccggctgt
gataacgcatccagcaaagagcccaaaacgaaccgaccgcctattggcaaccattgtgct
gataaactaactgcagtccagcattccagtagcaagtcttcctcggaacctactttgtct
atttctccttcaagaccaaccactttaagtttagatctcactaaaaactctgtggaaaaa
ctccaacccagttcaccaaaggtgtatctttacatccagatgcagctgtgcagaaaggaa
aacctcaaagactggctgaacagccgctgcaccattgaggaaagagagaggagcgtgtgt
ctgcacatcttcctgcagatcgcggaggcggtggagtttctgcacagcaaagggctcatg
cacagggacctcaagccttccaacatattctttacaatggatgatgtggtcaaggttgga
gactttggattggtgactgcaatggaccaggatgaagaagaccagctggttctgacccca
atgccagggtacgccagacacacaggacaagtggggaccaagctgtatatgagcccagaa
cagattcatggcaacaactactctcataaagtggacatcttttctttaggcctcattctg
tttgaattgctgtatccgttcggcactcatatggagagggtcaggatcttaactgatgta
agagatctcaaatttccaccactatttactcagaaatatcctcgtgagtatgtaatggtg
caagacatgctctccccatcccctacggaacggcctgaagctgcaaacattattgaaaat
gctatattcgaggacttggagtttccaggaaaaacagttctcagacagaggtctcgctcc
atgagctcatcaggaacaaaacagtcaagacactccagcagctcccacagccctttgcca
agcaattag
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