KEGG   Orcinus orca (killer whale): 101286197
Entry
101286197         CDS       T05247                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein isoform X2
  KO
K13375  transforming growth factor beta-1
Organism
oor  Orcinus orca (killer whale)
Pathway
oor04010  MAPK signaling pathway
oor04060  Cytokine-cytokine receptor interaction
oor04068  FoxO signaling pathway
oor04110  Cell cycle
oor04148  Efferocytosis
oor04218  Cellular senescence
oor04350  TGF-beta signaling pathway
oor04380  Osteoclast differentiation
oor04390  Hippo signaling pathway
oor04518  Integrin signaling
oor04659  Th17 cell differentiation
oor04672  Intestinal immune network for IgA production
oor04926  Relaxin signaling pathway
oor04932  Non-alcoholic fatty liver disease
oor04933  AGE-RAGE signaling pathway in diabetic complications
oor05140  Leishmaniasis
oor05142  Chagas disease
oor05144  Malaria
oor05145  Toxoplasmosis
oor05146  Amoebiasis
oor05152  Tuberculosis
oor05161  Hepatitis B
oor05166  Human T-cell leukemia virus 1 infection
oor05200  Pathways in cancer
oor05205  Proteoglycans in cancer
oor05210  Colorectal cancer
oor05211  Renal cell carcinoma
oor05212  Pancreatic cancer
oor05220  Chronic myeloid leukemia
oor05225  Hepatocellular carcinoma
oor05226  Gastric cancer
oor05321  Inflammatory bowel disease
oor05323  Rheumatoid arthritis
oor05410  Hypertrophic cardiomyopathy
oor05414  Dilated cardiomyopathy
oor05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oor00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101286197 (TGFB1)
   04350 TGF-beta signaling pathway
    101286197 (TGFB1)
   04390 Hippo signaling pathway
    101286197 (TGFB1)
   04068 FoxO signaling pathway
    101286197 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    101286197 (TGFB1)
   04518 Integrin signaling
    101286197 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101286197 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    101286197 (TGFB1)
   04218 Cellular senescence
    101286197 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    101286197 (TGFB1)
   04672 Intestinal immune network for IgA production
    101286197 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    101286197 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101286197 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101286197 (TGFB1)
   05205 Proteoglycans in cancer
    101286197 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101286197 (TGFB1)
   05212 Pancreatic cancer
    101286197 (TGFB1)
   05225 Hepatocellular carcinoma
    101286197 (TGFB1)
   05226 Gastric cancer
    101286197 (TGFB1)
   05220 Chronic myeloid leukemia
    101286197 (TGFB1)
   05211 Renal cell carcinoma
    101286197 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101286197 (TGFB1)
   05161 Hepatitis B
    101286197 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    101286197 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101286197 (TGFB1)
   05144 Malaria
    101286197 (TGFB1)
   05145 Toxoplasmosis
    101286197 (TGFB1)
   05140 Leishmaniasis
    101286197 (TGFB1)
   05142 Chagas disease
    101286197 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    101286197 (TGFB1)
   05321 Inflammatory bowel disease
    101286197 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    101286197 (TGFB1)
   05414 Dilated cardiomyopathy
    101286197 (TGFB1)
   05415 Diabetic cardiomyopathy
    101286197 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    101286197 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101286197 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:oor03110]
    101286197 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:oor04052]
    101286197 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:oor00536]
    101286197 (TGFB1)
Chaperones and folding catalysts [BR:oor03110]
 Intramolecular chaperones
  Others
   101286197 (TGFB1)
Cytokines and neuropeptides [BR:oor04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   101286197 (TGFB1)
Glycosaminoglycan binding proteins [BR:oor00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   101286197 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 101286197
NCBI-ProteinID: XP_004271297
LinkDB
Position
20:complement(47356537..47371156)
AA seq 390 aa
MPPSGLRLLPLLLPLLWLLVLPPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDQVAGESAEPEPEPEADYYAKEVTRVLMVENSNEI
YGKIKRSPHSMYMLFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNDSWR
YLSNRLLAPSDSPEWLSFDVTGVVRQWLTHGEEIEGFRLSAHCSCDSKDNTLQVDINGFS
SGRRGDLATIHGMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQA
LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgccgccctcggggctgcggctgctgccgctgctgctgccgctgctgtggctactagtg
ctgccgcctggccggccggccgccggactgtccacctgcaagaccatcgacatggagctg
gtgaagcgaaagcgcatcgaggccatccgcggccagattctgtccaagcttcggctcgcc
agccccccgagccagggggaggtgccgcccggtccgctgcccgaggccgtactggctctt
tacaacagtactcgtgaccaggtggccggggaaagtgccgaacctgagcctgagccagag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaaaacagcaacgaaatc
tatgggaaaatcaagcgtagtccacacagcatgtatatgctcttcaacacgtcggagctc
cgggaagcggtgcccgaacctgtgttgctctctcgggcagagctgcgcctgctgaggctc
aagttaaaagtggagcagcacgtggagctgtaccagaaatacagcaatgattcctggcgc
tacctcagcaaccggctgctggcccccagcgactcgccggagtggctgtcctttgacgtc
actggagttgtgcggcagtggctgacccacggagaggaaatagagggctttcgcctcagt
gcccactgttcctgtgacagcaaagataacacactccaagtggacattaacgggttcagt
tccggccgccggggtgacctcgccaccattcatggcatgaaccggcccttcctgctcctc
atggccaccccgctggagagggcccagcacctgcacagctcccggcaccgccgagccctg
gacaccaactactgcttcagctccacggaaaagaactgctgcgttcggcagctctacatt
gactttcgcaaggacctgggctggaagtggattcacgaacccaagggctaccacgccaat
ttctgcctggggccctgcccctacatctggagcctggacacgcagtacagcaaggtcctg
gccctgtacaaccagcacaacccgggcgcgtcggcggcgccgtgctgcgtgccgcaggcg
ctggagccgctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctgtcc
aacatgatcgtgcgctcctgcaagtgcagctga

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