Orcinus orca (killer whale): 101289268
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Entry
101289268 CDS
T05247
Symbol
PTPN6
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 6 isoform X2
KO
K05697
tyrosine-protein phosphatase non-receptor type 6 [EC:
3.1.3.48
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor04148
Efferocytosis
oor04520
Adherens junction
oor04630
JAK-STAT signaling pathway
oor04650
Natural killer cell mediated cytotoxicity
oor04660
T cell receptor signaling pathway
oor04662
B cell receptor signaling pathway
oor05140
Leishmaniasis
oor05205
Proteoglycans in cancer
oor05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101289268 (PTPN6)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101289268 (PTPN6)
09144 Cellular community - eukaryotes
04520 Adherens junction
101289268 (PTPN6)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
101289268 (PTPN6)
04660 T cell receptor signaling pathway
101289268 (PTPN6)
04662 B cell receptor signaling pathway
101289268 (PTPN6)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
101289268 (PTPN6)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101289268 (PTPN6)
09174 Infectious disease: parasitic
05140 Leishmaniasis
101289268 (PTPN6)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
oor01009
]
101289268 (PTPN6)
Enzymes [BR:
oor01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
101289268 (PTPN6)
Protein phosphatases and associated proteins [BR:
oor01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
101289268 (PTPN6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Y_phosphatase
SH2
PTP-SAK
Tc-R-P
SH2_1
DSPc
PTPlike_phytase
Y_phosphatase3
PTP-NADK
HGAL
Motif
Other DBs
NCBI-GeneID:
101289268
NCBI-ProteinID:
XP_004279125
LinkDB
All DBs
Position
11:6915908..6930979
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AA seq
595 aa
AA seq
DB search
MVRWFHRDLSGLDAETLLKGRGVNGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDF
YDLYGGEKFATLAELVEYYTQQQGVLQDRDGTVIHLKYPLNCSDPTSERWYHGHMSGGQA
ETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPDSPLRVTHIKVMCEGGRYTVGG
SETFDSLTDLVEHFKRTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESENTA
KAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHSRVVLQGRDSNIPGSD
YINANYVKNQLLGPDENAKTYIASQGCLEATVNDFWQMVWQENTRVVVMTTREVEKGRNK
CVPYWPEVGTQHVYGLYAVTNCREHDAAEYKLRTLQVSPLDNGDLVREIWHYQYLSWPDH
GVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGLDC
DIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVMQSQKGWESEYGNIT
YPPAMKNAHAKAARTSSKHKEDVYENVHSKNKKDEKVKKQRSADKEKSKGSLKRK
NT seq
1788 nt
NT seq
+upstream
nt +downstream
nt
atggtgaggtggtttcaccgagacctcagtgggctggatgccgagaccctgctcaagggc
cgaggggtcaacgggagcttcctggctcggcccagtcgcaagaaccagggcgacttctcc
ctctccgtcagggtgggggatcaggtgacccacattcggatccagaactcgggggatttc
tacgacctgtatggaggggagaagttcgcgacgctggcagagctggtggagtactacacg
cagcagcagggcgtcctgcaggaccgcgatggtaccgtcatccacctcaagtacccgctg
aactgctcagaccccaccagtgagaggtggtaccatggccacatgtctggagggcaggca
gagacactgctgcaggccaagggtgagccctggacttttctcgtgcgtgaaagtctcagc
cagcctggagattttgtgctgtccgtgctcagcgaccagcccaaggctgggccggactcc
cctctcagagtcacccacatcaaggtcatgtgtgagggtggacgctacacagtgggcggt
tcggagaccttcgacagcctcacggacctggtggagcatttcaagaggacggggatcgag
gaggcctcgggcgccttcgtctacctgcggcagccgtattacgccacgagggtgaacgca
gctgacattgagaaccgggtcttggaactgaacaagaagcaggagtcggagaacacagcc
aaggctggcttctgggaggagtttgagagtctgcagaagcaggaggtgaagaacttgcac
cagcggctggaagggcagcggccagaaaacaagagcaagaaccgttacaagaacatcctt
ccgttcgaccacagccgagttgtcctgcagggacgcgacagtaacatccctgggtccgac
tacattaacgccaactacgtcaagaaccagctgctaggccctgatgagaatgctaagacc
tacatcgccagccagggctgcctggaggccacagtcaacgacttctggcagatggtgtgg
caggagaacacccgtgtcgtcgtcatgaccacccgggaggtggagaagggccggaacaaa
tgtgtcccatactggccagaggtgggcactcagcacgtttatggactctacgctgtaacc
aactgcagggaacacgacgcagctgagtacaaactccgcaccttacaggtctccccgctg
gacaatggggacctggttcgggagatctggcactaccagtacctgagctggcctgaccac
ggggtccccagcgagcctgggggtgtcctcagcttcctggaccagatcaaccagcggcag
gaaagtctgcctcacgcagggcccatcatcgtgcactgcagcgccggcattggccgcacc
ggcaccatcattgtcatcgacatgcttatggagagcatctccaccaagggcctggactgt
gacatcgacatccagaagacgatccagatggtacgggcccagcgctcgggcatggtgcag
acggaggcgcagtacaagttcatctacgtggccatcgcccagttcatcgaaaccaccaag
aagaagctggaggtcatgcagtcccagaagggctgggagtcggagtacgggaacattacc
taccccccagccatgaagaatgcccatgccaaggccgcccgcacctcctccaaacacaag
gaggacgtgtatgagaacgtgcacagtaagaacaagaaggacgagaaggtgaagaagcag
cggtcggcggacaaggagaagagcaagggttccctgaagaggaagtga
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