Ochotona princeps (American pika): 101517017
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Entry
101517017 CDS
T07609
Symbol
ABL1
Name
(RefSeq) tyrosine-protein kinase ABL1 isoform X1
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi04012
ErbB signaling pathway
opi04014
Ras signaling pathway
opi04110
Cell cycle
opi04360
Axon guidance
opi04517
IgSF CAM signaling
opi04722
Neurotrophin signaling pathway
opi05200
Pathways in cancer
opi05206
MicroRNAs in cancer
opi05208
Chemical carcinogenesis - reactive oxygen species
opi05220
Chronic myeloid leukemia
opi05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101517017 (ABL1)
04014 Ras signaling pathway
101517017 (ABL1)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
101517017 (ABL1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
101517017 (ABL1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
101517017 (ABL1)
09158 Development and regeneration
04360 Axon guidance
101517017 (ABL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101517017 (ABL1)
05206 MicroRNAs in cancer
101517017 (ABL1)
05208 Chemical carcinogenesis - reactive oxygen species
101517017 (ABL1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
101517017 (ABL1)
09166 Cardiovascular disease
05416 Viral myocarditis
101517017 (ABL1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
opi01001
]
101517017 (ABL1)
Enzymes [BR:
opi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101517017 (ABL1)
Protein kinases [BR:
opi01001
]
Non-receptor tyrosine kinases
ABL family
101517017 (ABL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
Kinase-like
SH3_6
ABC1
Motif
Other DBs
NCBI-GeneID:
101517017
NCBI-ProteinID:
XP_004593535
LinkDB
All DBs
Position
1A:complement(1752438..1864928)
Genome browser
AA seq
1145 aa
AA seq
DB search
MGQQPGKVLGDQRRPSLPALHFIKGSGKKESATRHGGPHCNVFVEHEALQRPVASDFEPP
GLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWC
EAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQ
RSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHCTVADGLITTLHYPAPKR
NKPTIYGVSPSYDKWEMERTDIAMRHRLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEV
EEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVL
LYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAK
FPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMER
PEGCPEKVYGLMRACWQWNPSERPSFAEIHQAFETMFQESSISDEVEKELGRRGTRGAMS
TLLQAPELPTKTRTSRRAAEPRDTTDTSDAPHSKGPIESDALDHEPAVSPLLPRKERGPP
DGGLNEDERLLPKDKKTNLFSALIKKKKKTAPAPPKRSSSFREMDGAPERRGPGEDEARE
MSNGAAPAPATDTAEPTKCPKPSNGGNGVPNGACRESGGSGFRSPHLWKKSSTMSSSRLA
AGEEESSGSSGKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKTEK
PALPRKRASENKSDQAPRGTVTPPPRLGKKSEEAVDEAFRDPAEASPGSSPPGLTPKLQR
RQVPASPASGPPHKEEAGKGGAPGAPGAAEPVPPTSRAGPSKGPMEESRVRRNKHSSESP
GRDKGKLSKLKPAPPPPPASVGKAGKPSLSPSQEAAGEAAAGGKTKSTSQAVDPAGGEAA
KPSQPGDGVKKLLPPSAPKPQAATKAAGTPTSPAPSPASLPSASTALAGDQASSTAFIPL
ISTRVSLRKTRQPPERLASGAITKGVVLDSTEALCLAISRNSEQVGSHSAVLEAGKNLYT
FCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAAGGPAASPDFSKLLGSVKEIS
DIVQR
NT seq
3438 nt
NT seq
+upstream
nt +downstream
nt
atggggcagcagcctggaaaagttcttggggaccaaaggaggccaagtttgcccgccctg
cacttcatcaaagggtcagggaagaaggagtcggccacgaggcatgggggcccacactgc
aacgtgtttgtggaacacgaagcccttcagaggccggtggcatctgacttcgagcccccg
ggtctgagcgaagctgctcgttggaactccaaggaaaacctgcttgctgggcccagtgaa
aatgaccccaatctgtttgttgcgctgtatgatttcgtggccagtggggacaacacccta
agcataactaaaggtgaaaagcttcgggtcttgggctacaaccacaatggggaatggtgt
gaagcgcaaaccaaaaatggccaagggtgggtcccgagcaactacatcacgccagtcaac
agcctggagaagcactcgtggtaccacgggcccgtgtcacgcaacgcggccgagtacctg
ctgagcagcggcattaacggcagcttcctggtgcgggagagcgagagcagccctggccag
aggtccatctccctgcgatatgaagggagggtctaccactaccgcatcaacaccgcgtcc
gatggcaagctctatgtctcctcggagagccgcttcaacaccctggccgagctggtccat
caccactgcaccgtggccgacggcctcatcaccaccctgcactacccagcccccaagcgt
aacaagcccaccatctacggcgtgtcccccagctatgacaagtgggagatggagcgcacc
gacatcgccatgcggcaccggctgggcgggggccagtacggggaggtgtatgagggcgtg
tggaagaagtacagcctgaccgtggccgtgaagaccctgaaggaggacaccatggaggtg
gaggagttcttgaaagaagctgcagtgatgaaagagatcaaacaccctaacctggtgcag
ctgctcggggtctgcacacgggagcctcctttctacatcatcaccgagttcatgacctac
gggaacctgctggactacctgcgcgagtgcaaccggcaggaggtgaacgccgtggtgctg
ctgtacatggccacgcagatctcctctgccatggagtacctggagaagaagaacttcatc
cacagggatctggctgcccgcaactgcctggtcggggagaaccacctggtgaaggtggcc
gacttcgggctgagccggctgatgacgggggacacctacacggcccacgctggggccaag
ttccccatcaagtggaccgcgccggagagcctggcctacaacaagttctccatcaagtcc
gacgtctgggcgtttggcgtactgctctgggagattgccacctacggcatgtcaccttac
cctgggatcgacctgtcccaggtctacgagctgctggagaaggactaccgcatggagcgc
cctgaaggctgcccggagaaggtctacggactcatgcgcgcatgttggcagtggaacccc
tcggaacggccctcctttgccgaaatccaccaggctttcgaaacgatgttccaggaatcc
agtatctcagatgaagtggaaaaggagctgggccgacgtggcacccggggggccatgagc
accctgcttcaggccccagagctgcccaccaagacccgaacgtccagaagagctgctgag
ccccgagacaccactgacacctcagatgcaccccactccaagggtccaattgagagcgat
gccctggaccatgaacctgccgtgtctccgctgctcccacgaaaagagcggggtccccca
gacggcggcctgaacgaagatgagcgccttctccccaaagacaagaaaaccaacctgttc
agcgccttgatcaagaagaagaagaagaccgcgccggcccccccgaagcgcagcagctcc
ttccgggagatggacggcgctcccgagcgcagggggcccggcgaggacgaggcccgggag
atgagcaacggggcggcccccgctcccgccacagacacggccgagcctaccaagtgcccc
aagcccagcaacggaggcaatggagtccccaacggggcctgccgggagtcggggggctca
ggcttccgctccccccacctgtggaagaagtccagcaccatgagcagcagccgcctggca
gctggcgaggaggagagcagcggcagctctggcaagcgcttcctgcgctcctgctcagcc
tcctgcgtgccacatggggccaaggacaccgagtggaggtcagtcacgctgccccgcgac
ctgcagtccacgggcaggcagttcgattcgtccaccttcggagggcacaaaaccgagaag
cccgctttgccccggaagcgggccagcgagaacaagtctgaccaggcgcccaggggcacg
gtgacccctccaccccggctgggaaagaagagcgaggaagccgtggatgaggccttcaga
gaccccgccgaggccagcccaggctccagccctcccggcttgaccccgaagctccagcgg
cggcaggtcccagcgagccctgcctctggccccccgcacaaggaagaggccgggaagggc
ggtgccccgggggcccctggcgctgcagaaccagtgccccccaccagcagagcaggcccc
agtaagggccccatggaggaatcccgagtgcggaggaacaagcattcctctgagtcgcca
ggcagagacaaggggaagttgtccaagctcaaaccggccccaccaccaccgccagcctcc
gtgggcaaagcggggaagccctcactgagcccgagccaggaggcggctggggaggcagct
gctggcggtaaaacaaaatccaccagccaggcggtggatccggccggcggcgaggctgcc
aagcccagccagccaggggacggtgtgaaaaagctcctgcccccgtcggcaccgaagccg
caggcggccaccaaggctgcggggacccccaccagcccggcccccagccccgcctcgctg
ccttcggcctccacagccctggccggggaccaggcgtcttccaccgccttcatccccctc
atctcgacccgcgtgtctctgaggaaaacccgccagcccccagagcgccttgccagtggc
gccatcaccaagggcgtggttctggacagcaccgaggccctgtgcctggccatctccaga
aactcggagcaggtgggcagccacagtgccgtgctggaggccggcaagaacctctacacc
ttctgcgtgagctacgtggattccatccagcaaatgaggaataagttcgccttccgggag
gccatcaacaagctcgagaacaacctacgggagctgcagatctgcccggccacggcggcg
ggcggcccggcagccagcccggacttcagcaagctcctgggctccgtgaaggagatcagt
gacatagtgcagaggtag
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