Ochotona princeps (American pika): 101519464 Help Entry 101519464         CDS       T07609                                  Symbol TSC2 Name (RefSeq) tuberin isoform X2   KO K07207   tuberous sclerosis 2 Organism opi  Ochotona princeps (American pika) Pathway opi04072   Phospholipase D signaling pathway opi04115   p53 signaling pathway opi04140   Autophagy - animal opi04150   mTOR signaling pathway opi04151   PI3K-Akt signaling pathway opi04152   AMPK signaling pathway opi04211   Longevity regulating pathway opi04218   Cellular senescence opi04714   Thermogenesis opi04910   Insulin signaling pathway opi04919   Thyroid hormone signaling pathway opi05163   Human cytomegalovirus infection opi05165   Human papillomavirus infection opi05168   Herpes simplex virus 1 infection opi05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:opi00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     101519464 (TSC2)    04151 PI3K-Akt signaling pathway     101519464 (TSC2)    04152 AMPK signaling pathway     101519464 (TSC2)    04150 mTOR signaling pathway     101519464 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101519464 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     101519464 (TSC2)    04218 Cellular senescence     101519464 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101519464 (TSC2)    04919 Thyroid hormone signaling pathway     101519464 (TSC2)   09149 Aging    04211 Longevity regulating pathway     101519464 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     101519464 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     101519464 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     101519464 (TSC2)    05163 Human cytomegalovirus infection     101519464 (TSC2)    05165 Human papillomavirus infection     101519464 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:opi01009]     101519464 (TSC2) Protein phosphatases and associated proteins [BR:opi01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      101519464 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  101519464 NCBI-ProteinID:  XP_004596681 LinkDB All DBs Position 1:complement(114283770..114310711) Genome browser AA seq 1817 aa AA seqDB search MAKPSSKDSGLREKFKTLLGLGTARAQHPRAAEGKQTEFVITTDVLRELSVECGINNRIR VIGQICEVARTKKFEEHAVEALWKAVADLLQPERPPEARHAVLALLKAIIQGQGDRLGVL RALFFRVIKDYPSSEDLHERLEVFKALTDNGRHIAYLEEELAEFVLQWMDVGLSSEFLLV LVNLIKFNSCYLDEYIASMVHMICLLCIRTASSVDIEVSLQVLDAVVCYNCLPAESLPQF IITLCRTVNVKELCEPCWKLMRNLLGTHLGHSAIYNMCRVMENRAYMEDAPLLRGAVFFV GMALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLVKKYRKELQAVTWD LLLNIVERLLQQLQSLDSPELRTIVHDLLTTVEELCDQNEFHGSQERFFELVERCADQRP ESSLLNLVSFRAQSIHPARDGWIQSLQLLMERFFRSEPRSAVRIKVLDVLSFVLLINRQF YEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLEIIEKVMARSL SAPPELEERDVTSHSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYETLVGHLQLHYK HNYALPIASSIRLQAFDFLLLLRADSLHRLGLPSKDGGVRFSPYCFCDCVEPERGSEKNA GGSLSPPTGPSGPAPAGPTVRLGYLPYSLLFRLLLQCLKQEADWKVLKLVLSRLPESLRY KVLFFTSPCSLDQLASALCSMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHKY LDKSKQREMVYCLEQGLIHRCAGQCVVALAVCSVEMPDVIVKTLPVLVVKLTHISATASM AAPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIR CRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPRQGLTH SPPMEECEGSPTAEAFRCRSVSVSEHAVRSRVQTSLTSASLGSADENSMAQADDSLKNLH LELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRS LLGLDSGELQGSGPETSADPGTHIRQTKEAPAKLESQAGQQVSCGARDRVRSMSGGHGLR AVGLDTLASHFSAGPCSPGAPMMPSAKADRASAGPQGLAPERMNLAAYVPLLTQGWAEIL VRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAA STARPPPLPRSNTVASLSSLCPSGCQGKLHRSISWADSAVLPEESAAPLPPEPPELEDVE VAVLGSQGRCGRAAVYSRSSSASSQEEKPFRSEERAVCGVPIEQAGSAASGRPAVGLSFQ PSQPLSKSSSSPELQTLQDVLGEAGDKVDGGRLSPEAKARSQSGTLDRDGAAWAAPDEEG QGLGPAQPEGGLPSSSPRSPGGLRPRGYTISDSAPSRRGRRADRVERDALKGRAAASSAE KVPGINPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGE GQSNSELAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHD DIMQAVFHIATLMPTKDGDKHQCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVI ITPLDYECNLVSLQCRKDMEGLVDTSMAKIVSDRNLPFVARQMALHANMASQVHHSRSNP TDVYPSKWIARLRHIKRLRQRVREATQYSSSSLPLMQIHNPAHAKAPMQVPAEPLSTYET GQRKRLISSVDDFTEFV NT seq 5454 nt NT seq  +upstreamnt  +downstreamnt atggccaagccgagcagcaaggattccggcttgagggagaagttcaagaccctgttgggg ctggggacggcgagggcgcagcaccccagggcggcggaaggcaagcagaccgagttcgtc atcaccaccgacgtcctcagagaactgagtgttgagtgtggtatcaataatcgcatccgg gtcatagggcagatctgtgaagttgcaagaaccaagaagtttgaggagcatgcagtggaa gccctctggaaagccgttgctgatctgctgcagccggagcggccccctgaagcccggcac gctgtgctggccctgctgaaggccatcatccaggggcagggggaccgcttgggggttctc agggcgctgttcttcagggtcatcaaggattacccttccagcgaagacctacacgagagg cttgaggtgttcaaggcgctcacagacaacgggcggcacattgcgtatctggaggaggaa ctggcggagttcgtcctgcagtggatggatgtcggcctgtcctccgagttcctgctggtg ctcgtgaacttgatcaagtttaacagctgttaccttgacgaatacatcgcttccatggtt cacatgatctgcctgttgtgcattcggactgcgtcctctgttgatattgaggtgtccctg caggtgctggacgccgtggtctgctacaactgcttgcctgcggagagcctcccacagttc atcatcacactgtgtcgcacagtgaatgtcaaggagctctgtgagccctgctggaagctg atgcggaacctcctgggcacccacctgggccacagcgccatttacaacatgtgccgcgtc atggagaacagagcctacatggaggatgccccactactgcgaggagctgtgttcttcgtg ggcatggccctctggggagcccaccgcctctactcgctcaagaactcgccgacatctgtg ctgccatccttttatgaggccatgacttgtcccaatgaggtggtgtcctatgagatcgtg ctgtccatcaccaggcttgtcaagaagtacagaaaggagctgcaggctgtgacgtgggac ctgctgctcaacattgtggagcggctgctgcagcagctccagagcctggacagcccggag ctcaggaccatcgtgcatgacctgctgaccacagtggaggaactgtgtgaccagaatgag ttccatggctcccaggagagattcttcgagctggtggagagatgtgcagaccagaggcct gagtcctccctcttgaacttggtctccttccgggcacagtccattcaccctgcgagggac ggctggatccagagcctgcagctgctcatggagcgcttcttcaggagcgaaccccgcagc gctgtgcgcatcaaggtgctggacgtgctgtcctttgtgctgctcatcaacagacagttc tatgaggaggagctcatcaactccgtggtcatctcccagctctcccatatccccgaggat aaggaccaccaggtccggaagctggctacccagttgctggtggacctggcggaaggctgc cacacccaccacttcaacagtttgctggagatcattgagaaagtgatggcgcgctccctc tctgcaccgcctgagctggaggaaagggatgtgacctcccactcggcttccctggaggac gtgaagactgctgtcctggggctcctggtcatcctgcagaccaagctgtacactttgcct gccagccatgccacacgcgtgtatgagacgctcgtcggccacctgcagctgcactacaag cacaactacgcgctgcccattgccagcagcatccggttgcaggcctttgatttcctgctg ctgctgcgcgccgactcgctgcaccgcctgggtctgcccagcaaggatgggggcgtgagg ttcagcccctactgcttctgcgactgcgtggagccagagcggggctctgagaagaatgcc ggcggctccctctcgcctcccacggggccttctggtccagcccctgcaggccctactgtg cgactgggctacctgccctactcactgctctttcgcctcctactgcagtgtttgaagcag gaggctgactggaaggtgctgaagctggtgctcagcaggctgcccgagtcgctgcgctac aaggtgctcttcttcacctcgccctgcagcctcgaccagctggcctccgcactctgctcc atgctttcaggcccaaagacactcgagcggctccgggggacgccggagggcttctccagg actgacctgcacctggccgtggtcccagtgctgacggcgttaatctcttaccacaagtac ctggacaagagcaagcagcgggagatggtctattgcctggagcagggactcattcaccgc tgtgcgggccagtgcgtggtggccctggctgtgtgcagcgtggagatgcccgatgtcatc gtcaagacgctgcccgtgctggtggtaaagctcacacacatctcggccacggccagcatg gctgccccgctgcttgagttcctgtctactctggccaggctgccacacctctacaggaac tttgcggcagagcagtatgcgagtgtgttcgccatctccctgccttacaccaacccctcc aagttcaatcagtacatcgtgtgcctggctcatcatgtcatagccatgtggttcatcagg tgtcgcttgcctttccggaaggattttgtcccttacatcactaagggtctgcgctctaac gtgctgctgtcgtttgatgacacccctgagaaggacagcttccgggctcgtagcaccagc ctcaacgagagacccaaaagtctgaggatagccagaccccccagacaaggcttgactcac tccccacccatggaggagtgcgaggggagtcctaccgccgaggccttccgctgccgcagc gtcagtgtgtctgaacatgcggtccgcagcagagtccagacgtccctcaccagcgccagc ctgggctccgcagacgagaattccatggcccaggccgacgacagcttgaagaacctccac ctggagctcacggagacgtgtctggacatgatggcccgatacgtgttttccaacttcacc gccgtgcccaagaggtctcctgttggagagttcctcctggcaggcggcaggaccaaaacc tggctggtgggaaacaagcttgtcactgtgacgacgagtgtgggcactgggacccgctcg ctgctgggcctggattccggggaactgcagggcagcggcccagaaacgagcgctgacccg ggcacacacatccgacagaccaaggaggcgccggccaagctggagtcgcaggccggccag caggtgtcttgtggggcccgggaccgcgtccgctccatgtcgggaggccatggccttcgt gctgtcggcctagacacgctggcctcccacttctcagctggcccctgctctccgggagca ccgatgatgccatccgccaaggctgacagggcctcggcaggcccccagggcctggctccg gagaggatgaacctggcggcctacgtgcccctgctgacccagggctgggcggagatcctg gtccgcaggcccacagggaacacgagctggctgatgagcctggagaacccgctgagcccc ttttcctcggacatcaacaacatgcccctgcaggagctgtccaacgccctcatggcggcc gaacgcttcaaggagcaccgcgacaccgccctctacaagtcgctgtcggtgccagcagcc agcacggccaggcccccgcctctccctcgctccaacacagtggcctccctgtcctctctg tgcccgtccggctgccaagggaagctgcacaggagcatttcctgggcagactcggccgtg cttccagaggagagcgcagccccgctgccgccagagccccctgagctggaggacgtggaa gtggccgtgctaggcagccaggggcgctgtggccgtgctgctgtctatagccggtcatcc tcagcgtccagtcaggaggagaagccgttccgcagtgaggagcgggccgtctgtggcgtc cccatcgagcaggctggctccgctgccagtggccggccggcggtgggcctctccttccag ccttcgcagcctctcagcaagtccagctcctcccccgagctgcagacgctgcaggacgtc ctgggggaggccggggacaaggttgatggtggccggcttagtcccgaggccaaggcccgg tcacagtcagggaccctcgacagagatggtgctgcctgggcagccccggatgaggagggc cagggcttgggccctgcacagcctgaggggggcctgccatccagctcgccccgctccccc ggcggcctgcggccccgcggctacaccatctccgactcggccccatcacgcaggggcagg agggccgacagggtggaacgggacgccctcaagggcagggctgcggccagcagcgccgag aaggtgccgggcatcaaccccagcttcgtgttcctgcagctctaccactcgcctttcttt ggcgacgagtccaacaaacccatcctgctgcccaacgagtccttcgagcggtcagtgcag ctcctggaccagatcccatcctatgacacacacaagatcgctgtcctctacgtgggagag ggccagagcaacagcgagctggccatcttgtccaacgagcacggctcctaccgctacacg gagttcctgacggggctgggcaagctcatcgagctcaaggactgccagcccgacaaggtg tacctgggcggcctggacgtgtgcggcgaggacggccagttcacctactgctggcatgat gacatcatgcaggctgtgttccacatcgccaccctgatgcccaccaaggacggggacaag caccagtgtgacaagaaacgccacctgggcaacgacttcgtctctattgtctacaatgac tctggtgaggacttcaagctgggcaccatcaagggccagttcaactttgttcacgtgatt attaccccgctggactacgagtgcaacctggtgtcgctgcagtgccggaaagacatggag ggcctcgtggacaccagcatggccaagattgtgtctgaccgcaacctgcccttcgtggcc cgccagatggcactgcatgccaacatggcctcacaggtgcaccacagccgctccaacccc accgacgtctacccctctaagtggatcgcccggctgcggcacatcaagcgactccgccag cgggtccgtgaggccacccagtattccagctccagcctgcccctgatgcagatacacaac cctgcccacgccaaagcccccatgcaggtgccggctgagccgctgtccacctatgagact ggccagcggaagcgcctcatctcctccgtggatgacttcacagagttcgtgtga

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