Ochotona princeps (American pika): 101520691
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Entry
101520691 CDS
T07609
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi00220
Arginine biosynthesis
opi00330
Arginine and proline metabolism
opi01100
Metabolic pathways
opi04020
Calcium signaling pathway
opi04022
cGMP-PKG signaling pathway
opi04066
HIF-1 signaling pathway
opi04071
Sphingolipid signaling pathway
opi04151
PI3K-Akt signaling pathway
opi04370
VEGF signaling pathway
opi04371
Apelin signaling pathway
opi04611
Platelet activation
opi04915
Estrogen signaling pathway
opi04921
Oxytocin signaling pathway
opi04926
Relaxin signaling pathway
opi04931
Insulin resistance
opi04933
AGE-RAGE signaling pathway in diabetic complications
opi05415
Diabetic cardiomyopathy
opi05417
Lipid and atherosclerosis
opi05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
101520691 (NOS3)
00330 Arginine and proline metabolism
101520691 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
101520691 (NOS3)
04371 Apelin signaling pathway
101520691 (NOS3)
04066 HIF-1 signaling pathway
101520691 (NOS3)
04020 Calcium signaling pathway
101520691 (NOS3)
04071 Sphingolipid signaling pathway
101520691 (NOS3)
04022 cGMP-PKG signaling pathway
101520691 (NOS3)
04151 PI3K-Akt signaling pathway
101520691 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101520691 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
101520691 (NOS3)
04921 Oxytocin signaling pathway
101520691 (NOS3)
04926 Relaxin signaling pathway
101520691 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101520691 (NOS3)
05418 Fluid shear stress and atherosclerosis
101520691 (NOS3)
05415 Diabetic cardiomyopathy
101520691 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
101520691 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
101520691 (NOS3)
Enzymes [BR:
opi01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
101520691 (NOS3)
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Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
101520691
NCBI-ProteinID:
XP_004594483
LinkDB
All DBs
Position
7A:complement(8927301..8947026)
Genome browser
AA seq
1207 aa
AA seq
DB search
MGNLKSVGQDPGPPCGLGLGLGLGLCGKQGPASPTSTSEPSRAPASPPPTPPAPDHSSNS
PPLTRPPEGPRFPRVKNWEVGSITYDTLSAQAQQDGPCTQRRCLGSLVFPRKLQSRPCQG
APSPDQLLGQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQ
AWRNAPRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHVKYATNRGNLRSAITVFPQRYP
GRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAP
DEPPELFTLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGW
YMSTEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVT
IVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQ
PDPWKGSGAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQ
QLGRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGP
YNSSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRA
YPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDA
KAAARDIFSPKRSWKRQRYRLSTQTEGLQLLPGLIHVHRRKMFQATILSVENLQSSKSTR
ATILVRLDTRGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPPTEPVAVEQLEKGS
AGGPPPGWVRDPRLPPCTLRQALTFFLDITSPPSPRLLQLLSTLAEEPSEQQELEALSQD
PRRYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSIYPGEIHLT
VAVLAYRTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPSLPCILVGPGT
GIAPFRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYREEVQDAQQRGVFGRVLTA
FSREHDSPKTYVQDILRTELASEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGD
MELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDLP
GSDTPGS
NT seq
3624 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacctgaagagtgtgggccaggaccccgggccgccctgtggcctggggctggga
ctgggcctcgggctgtgcggtaagcagggcccagcctctccgacatccacatcagagccc
agtcgggcaccagcatcacccccaccgaccccaccggcaccagatcacagctccaacagc
cctccactcacccggcccccggaggggcccaggttcccccgagtgaagaactgggaggtg
ggcagcatcacctacgacaccctcagcgcccaggcacagcaggatggaccttgcacccaa
agacgctgcctgggttcccttgtatttccccggaaactgcaaagccggccctgccagggt
gctccatcccctgatcaactgctgggtcaggcccgggacttcatcaaccagtactacagc
tccatcaagagaagcggctcccaggcccatgaacaacggcttcaggaggtagaggccgag
gtggcagccacaggcacctaccaacttcgggaaagcgaactggtgtttggagccaagcag
gcctggcgcaatgctccccgctgcgtgggccggatccagtgggggaagttgcaggtgttc
gatgcccgggactgcaggtctgcacaggaaatgttcacctacatctgcaatcacgtcaag
tacgccaccaaccggggcaacctacgctcggccatcacagtgttcccccagcgctatccg
ggccgtggagacttccggatctggaacagccagctggtgcgctatgcaggctaccgacag
caggacggctccgtgcggggagacccagccaacgtagagatcaccgagctctgcatccag
catggctggaccccaggaaacggccgcttcgatgtgctgcccctgctgcttcaggcacca
gatgagcccccagaactcttcactctgcccccagagctggtcctggaggtgcccctggag
cacccaacgctggagtggttcgcagctctgggcctgcgctggtacgccctgccggcagtg
tccaacatgctgctggaaattgggggcctggagttccccgcggcccctttcagcggttgg
tacatgagcacagagatcggcacgcgcaacttgtgcgaccctcaccgctacaacatcctg
gaggatgtggccgtctgcatggacttggatacccggacaacatcatccctgtggaaagac
aaggcagccgtggaaatcaacctggctgtactgcacagttaccagctggccaaagtgacc
attgtggaccaccatgctgccacagcctccttcatgaagcaccttgagaatgagcagaaa
gccagagggggctgccctgccgactgggcctggatcgtgccccccatctcaggaagcctt
actcctgtcttccatcaggagatggtcaactacttcctgtcacctgccttccgctaccag
ccagacccctggaaggggagtggagccaagggcactggcatcaccaggaagaagaccttt
aaggaagtggccaatgccgtgaagatttctgcctcactcatgggcacagtgatggccaag
agagttaaggccacgatcctgtatggttctgagactggccgggcccagagctatgcacag
cagcttgggaggctcttccggaaggcctttgatccccgggttctgtgcatggatgaatat
gacgtcgtatcccttgaacacgagacactggtattggtggtgaccagcacatttgggaat
ggggatccaccagaaaatggagagagttttgctgcagccctgatggagatgtccggcccc
tacaacagttctcctcgaccagagcagcacaagagttacaaaatccgcttcaacagcgtc
tcctgctcagacccgctggtgtcctcttggcgacggaagaggaaggagtccagtaacaca
gacagtgcaggggctctgggcaccctcaggttctgcgtgtttgggctcggctcccgggca
tacccccacttctgtgcctttgctcgtgcggtggacacgcggctggaagagctgggcggg
gaaaggctcctgcagctgggccagggggatgagctctgcggccaagaggaggcctttcgt
ggctgggcccaggctgccttccaggcctcctgtgagactttctgtgtgggagaagatgcc
aaggccgctgcccgggacatatttagccccaaacggagctggaagcgtcagaggtaccgc
ctgagtacccagactgagggtctacagctgctgccaggtctgatccatgtgcacaggcgg
aagatgttccaggccaccatcctctcagtggaaaacttacaaagcagcaaatccacccgg
gccacgatcctggtgcgtctggacactagaggccaggaagggcttcagtaccagccaggg
gaccacataggagtctgcccacccaaccggcctggccttgtggaggcactgctgagtcgc
gtggaggatccgccaccacccaccgagcctgtggccgtggagcagctggagaagggcagc
gctggtggccctccaccaggctgggtgcgggacccccggctgcccccctgcacattgcgc
caggctctcaccttcttcctggacatcacttccccacccagccctcggctcctacaactg
ctcagcactctggccgaagagcccagtgaacagcaggagctggaggccctcagccaggac
ccccggcgctatgaggagtggaagtggttccgctgtcccacactactggaggtgctggaa
cagttcccatctgtggcgctgcctgcacccctgctcctcacccagctgcccctgctgcag
cccaggtactactcagtcagctcggcacccagcatctacccaggggagatccatctcact
gttgctgtgctggcctacaggacgcaggatgggctgggccccctgcactatggagtctgc
tccacatggctgagccaactcaaggctggagaccctgtgccctgcttcatcaggggggcc
ccctccttccggctgccacctgatcccagtttgccctgcatcctggtgggcccgggtacc
ggcattgccccattccggggtttctggcaggagcgtctgcatgacattgaaagcaaaggc
ctgcagcctgcccctatgacgttggtgttcggctgccgctgctcccagctagaccacctc
taccgcgaggaggtgcaggacgcccagcagcgtggggtgtttggccgcgtcctcaccgcc
ttctcccgggaacacgacagccccaagacctacgtgcaggacatcctgaggaccgagctg
gcgtctgaggtgcaccgcgtgctgtgcctcgaacgtggccacatgtttgtctgcggcgat
gtcaccatggcaaccagcgtcctgcagactgtgcagcgaatcctggcgaccgagggcgac
atggagctggacgaggctggtgacgtcatcggcgtgctgcgggatcagcaacgctaccac
gaggacattttcgggctcacgctgcgcacccaggaggtgaccagccgcatccgcacccag
agcttctctttgcaggagcggcagctgcggggcgccgtgccctgggcgttcgatctgccg
ggctcagacacgcccggctcctga
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