Ochotona princeps (American pika): 101520812
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Entry
101520812 CDS
T07609
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi00260
Glycine, serine and threonine metabolism
opi00630
Glyoxylate and dicarboxylate metabolism
opi00670
One carbon pool by folate
opi01100
Metabolic pathways
opi01200
Carbon metabolism
opi01230
Biosynthesis of amino acids
opi01240
Biosynthesis of cofactors
opi01523
Antifolate resistance
opi04981
Folate transport and metabolism
Module
opi_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
101520812 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
101520812 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101520812 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
101520812 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101520812 (SHMT2)
Enzymes [BR:
opi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
101520812 (SHMT2)
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
101520812
NCBI-ProteinID:
XP_004582986
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Position
4:18408546..18442503
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AA seq
504 aa
AA seq
DB search
MLPFSLLWAARPLQRCGQLVRSAVRAQHGKAAQTQAGEAVQGWSGQESLAASDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAHWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRVSATSIFFESMPYKLNPQTGLIDYDQLALTARLFRPRLIIAGTSAYSRLIDYARMREV
CDEVKAYLLADMAHISGLVAAKVIPSPFKYADVVTTTTHKTLRGARSGLIFYRKGVRTVD
AKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLQDPATSQ
RLAELRHRVQQFARAFPMPGFDEH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctctttgctctgggcagctcggcctctgcagaggtgcggccagctagtc
aggtcagctgtgcgggcccagcatggcaaggctgcccagacccaggccggggaagcagtg
cagggctggagcggccaggagagcctggcagccagtgaccctgagatgtgggagctgctg
cagcgggagaaggacaggcaatgccgcggcctggaactcatcgcttctgagaacttctgc
agccgcgctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagaggtactacgggggagcagaggtggtggatgagattgagctgctgtgccag
cgccgagccctggaagcttttgacctagatcctgctcactggggagtgaacgtccagccc
tactcggggtcgcctgccaatctggccgcctacactgcccttctgcagcctcacgaccgg
atcatggggctggacctacctgatgggggccacctcacccacggctacatgtcagatgtc
aagcgggtctcagccacctccatcttctttgaatctatgccttataagctgaatccccaa
accggcctcattgactatgaccagctggccctgactgcccgactcttccggccacgcctc
atcatagctggcaccagtgcctattcacggcttattgactacgctcgcatgagagaggtg
tgtgatgaggtcaaggcttacctgctggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcgcctttcaagtatgcggatgttgtcaccaccaccacgcacaag
accctgcgtggggccaggtcgggcctcatcttctaccggaagggagtgcggactgtggac
gccaagactggccgggaaatcccttacacgtttgaagaccggatcaactttgccgtgttc
ccgtccctacaggggggcccccacaaccacgccattgctgccgtagctgtggccctaaag
caggcctgcacccccatgttccgagagtattccctgcaggttctaaagaatgcccgggcc
atggctgacgctctgctggagcgaggctactccctggtgtccggtggcaccgacaaccac
ctggtgctggtggacctgcgacccaagggtctggatggagcgcgtgccgagcgggtgctg
gaacttgtgtctatcaccgccaacaagaacacctgccctggggaccgaagtgccatcacc
cccgggggcctgcggcttggggcgcccgccttgacctcacgacagttccgtgaggatgac
tttcggagagtcgtggacttcatagatgaaggagttaacattggtctggaggtcaagagc
aagactgccaagctccaggatttcaaatccttcctgctccaggacccagcaaccagccag
cggctggcagaactccgacaccgtgtgcagcagtttgccagggccttccccatgcctggc
ttcgatgaacactaa
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