Ochotona princeps (American pika): 101521104
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Entry
101521104 CDS
T07609
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi04217
Necroptosis
opi04380
Osteoclast differentiation
opi04620
Toll-like receptor signaling pathway
opi04621
NOD-like receptor signaling pathway
opi04630
JAK-STAT signaling pathway
opi04658
Th1 and Th2 cell differentiation
opi04659
Th17 cell differentiation
opi05145
Toxoplasmosis
opi05160
Hepatitis C
opi05161
Hepatitis B
opi05162
Measles
opi05164
Influenza A
opi05165
Human papillomavirus infection
opi05167
Kaposi sarcoma-associated herpesvirus infection
opi05168
Herpes simplex virus 1 infection
opi05169
Epstein-Barr virus infection
opi05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101521104 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101521104 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
101521104 (TYK2)
04621 NOD-like receptor signaling pathway
101521104 (TYK2)
04658 Th1 and Th2 cell differentiation
101521104 (TYK2)
04659 Th17 cell differentiation
101521104 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
101521104 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
101521104 (TYK2)
05160 Hepatitis C
101521104 (TYK2)
05171 Coronavirus disease - COVID-19
101521104 (TYK2)
05164 Influenza A
101521104 (TYK2)
05162 Measles
101521104 (TYK2)
05168 Herpes simplex virus 1 infection
101521104 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
101521104 (TYK2)
05169 Epstein-Barr virus infection
101521104 (TYK2)
05165 Human papillomavirus infection
101521104 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101521104 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
opi01001
]
101521104 (TYK2)
Enzymes [BR:
opi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101521104 (TYK2)
Protein kinases [BR:
opi01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101521104 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kdo
FERM_C_FAK1
Kinase-like
Motif
Other DBs
NCBI-GeneID:
101521104
NCBI-ProteinID:
XP_004595556
LinkDB
All DBs
Position
Unknown
AA seq
1180 aa
AA seq
DB search
MPLCQRRATPRGGQLDLDEAAPMAASGGVKVLLHWAGPRGGEPWVTFSEASLTAEEACVH
IAHRIGITPPCSHLFALFDAQAQVWLPPNHVLEVSRDAGLTLYFRMRFYFRNWHGMNGQE
PAVYRCGPPGTEATSERAQQGLQLLDSASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF
KNESLGMAFLHLCHLALGWGVPLEEVAGKISFKHCIPRSFRQHIRQNNALTRLRLRRVFR
RFLRAFQPGHLSPQAVMIKYLATLERLAPRFGSERVPACHLRLLAQAEAEACYIHDHRQS
PADPCDPVTPKPPTHEVLVTGTGGIQWRPVPEKVRARADSREGHPRARASLSGKEGRAPK
DAPSEQPAWTYFCDFQDITHLVLGEHHVSIHLQDNQCMELSLSSRAAALSFAALVDGYFR
LTTDSSHYLCHEVAPPRVVMSIQDGIHGPLLEPFVRAKLQPVDGLYLIHWSASHLYRLIL
TVAQRDPAPGDSAQSLRLRKFPIELRDGAFVLEGWARSFTSLRELQTALHGCSLRTGEDC
FPLRRCCLPGPRELSNLIVMRGPQATSRPFSLSQLSFHRIRQDEICQLSHLGQGTRTNVY
EGLLHVGGPEEDQVDSGEPPAPAGAQGQELRVVLKVLDVSHHDVALAFYETASLMSQVSH
VHLAFVHGVCVRGSENIMVTEFVEHGPLDVWLRRERGRVPMAWKVVVAQQLASALSYLED
KNLTHGNVCGRNILLARPGLAEGTSPFVKLSDPGVGLGVLSREERVDRIPWTAPECLPAG
AGSLSPAADKWGFGATLLEICFDGEAPLQGRSPSEKERFYQQHHRLPVPSCPELAALTGR
CLAYEPAQRPSFRTVLRDLTRLQPRDLVGVLTMNPDSPACDPTVFHKRYLKKIRDLGEGH
FGKVSLYCYDPTNDGTGEMVAVKALKAGCGPQLRSGWRREIHILRALYHQHIVNYKGSCE
DPGDKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHGQHYIHRDLAAR
NVLLDHDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKESKFYYASDVWSF
GVTLYELLTHCDSSLSPPKKFEELLGLTQGQMTVLRLTELLERGERLPRPDKCPCEVYLL
MKNCWETEASFRPTFQNLTPLLKTAHEKYQGQSASVFSVC
NT seq
3543 nt
NT seq
+upstream
nt +downstream
nt
atgcctttgtgccagcgaagggccacccccaggggtggccagttggacctggacgaagct
gcgcccatggctgccagtgggggcgtgaaggtgctgttgcactgggccgggccccgcggc
ggggagccctgggtcaccttcagcgaggcttcgctgacagccgaggaggcttgcgtccac
atcgcacacaggatcggcatcactccaccctgctcccatctcttcgctctctttgatgcc
caggcccaagtgtggctgcctccaaaccacgtcctggaggtgtccagggacgcgggtctc
acgctgtatttccgcatgaggttctacttccggaactggcacggcatgaatggccaggag
ccggccgtgtaccgctgcgggccacccgggaccgaggccacatccgagcgggcacagcag
gggctccagctcctggattctgcctcgtttgagtaccttttcgagcagggcaagcatgag
tttgtgaatgacgtggcctcgctgtgggagctgtcgagcgaggaggagatccaccacttc
aagaatgagagcctgggcatggccttcctgcatctgtgccacctggcgctgggctggggc
gtcccgctggaggaggtggctgggaagatcagcttcaagcactgcatcccgcgctctttc
cgccagcacatccgccagaacaacgccctcacccgcctgcgcctgcgccgcgtattccgc
aggttcctgcgggccttccagccgggccacctgtcaccacaggcggtcatgatcaagtac
ctggccaccctggagcgcctggctccccgctttggctcggagcgcgtgcccgcctgccac
ctgcgcctgctggcccaggccgaggccgaggcctgctacatccacgaccacaggcagagc
cctgcggacccctgtgaccctgtgacccccaagccccccacgcatgaggtgctggtgacg
ggcacgggtggcatccagtggcgcccagtcccagagaaggtgagagccagggccgacagc
agagaggggcatccccgggccagagccagcctgtctgggaaggaaggcagggcccccaag
gacgcgccctcggagcagcccgcatggacctacttctgcgactttcaggacatcacgcac
ctggtgctgggcgaacaccatgtcagcatccacttgcaggataaccagtgcatggagctg
agcctgtcctcccgggccgcggccctgtcctttgcggcgctggtggacggctatttccgg
ctcaccaccgactctagccattacctgtgccatgaggtggcacccccgcgcgtggtgatg
agcattcaggacggcatccacggacccctgctggagccgtttgtgcgggctaagctacaa
cccgtggatggcctctacctcatccattggagtgccagccacctctaccgcctcatcctg
accgtggcccagcgcgacccggcacctggcgacagcgcacagagcttgcgtctgcgcaaa
ttccccatcgagcttcgggatggagccttcgtgctggagggctgggcccgctccttcacc
agcctgcgggagctgcagaccgccctgcatggctgctcgctgcgaaccggggaggactgc
ttccccctgcgacgctgctgcctgccagggcctagagagctctcgaacctcattgtcatg
cgtgggccccaggccacgtccaggcctttcagcctcagccaactcagcttccaccggatc
cgccaggatgagatctgccagctgtcacacttgggccagggcacaaggacgaatgtgtac
gagggcctcctgcatgtggggggccccgaggaagaccaagttgacagtggggagccgcca
gccccagccggggcccagggccaggagctacgggtggtgctcaaagtgttggatgtcagc
caccatgacgttgccctggccttctacgagaccgccagcctcatgagccaggtgtcccac
gtccacctggccttcgtgcacggcgtctgtgtgcgcggctcggagaacatcatggtcacg
gagttcgtggagcacgggcccctggatgtgtggctgcggcgggagcggggccgcgtgccc
atggcctggaaggtggtggtggcccagcagctggccagcgccctcagctatctggaggac
aagaacttgacccatggaaacgtgtgtggccggaacattctgctggcccgccctgggctg
gctgaggggaccagtccctttgtcaagctcagcgacccaggcgtgggcctgggggtcctc
tccagagaagagcgggtggatcgcattccctggacagcccccgagtgcctgcctgccggg
gccggcagcctgagccctgctgctgacaagtggggcttcggggccacgctcctggagatc
tgcttcgatggggaggcccccctgcagggccgcagcccctccgagaaagaacggttctac
cagcaacaccacaggctgccagtgccctcatgccctgagctggccgcgctcacgggccgg
tgcctggcctacgagcctgcccagcgcccgtctttccgcaccgtcctgcgggacctcacg
cggctgcagcccagggatctggtgggtgtcttgaccatgaacccagactccccggcgtgt
gaccccacggttttccacaagcgctacctgaagaagatcagggacctgggtgagggccac
ttcggcaaggtcagcttgtactgctacgaccccacgaacgacggcacgggcgagatggtg
gcggtgaaggccctcaaggccggctgcgggccgcagctgcgctcgggctggaggcgcgag
atccacatcctgcgcgcgctctaccaccagcacattgtcaactacaagggcagctgcgag
gacccaggtgacaagtcggtgcagctcgtcatggagtacgtgcccctgggcagcctgcgg
gactacctgccccggcacagcgtcggcctggcccagctgctgctcttcgcccagcagatc
tgcgagggcatggcctacctgcatgggcagcattacatccaccgagacctagctgcccgc
aacgtgctgctggaccatgacaggctggtcaagattggggacttcggcctggccaaggcc
gtgcccgaaggccacgagtactaccgcgtgcgcgaggatggcgacagccccgtgttctgg
tacgcccccgaatgcctgaaggaatccaagttctactacgcttccgacgtgtggtccttc
ggtgtcactctgtacgaactgctcacgcactgtgactccagcctgagccccccgaagaag
ttcgaggagctcctagggctcactcaaggccagatgacagttttgaggctgaccgagtta
ctggaacgtggggagaggctgccgcggcccgacaagtgtccctgcgaggtctacctgctc
atgaagaactgctgggagaccgaggcctccttccgccccaccttccagaacctcacgccc
ctcctgaagacggcccacgagaagtaccagggccagtcagcttctgtgttcagcgtgtgc
tga
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integrated database retrieval system
