KEGG   Ochotona princeps (American pika): 101524465
Entry
101524465         CDS       T07609                                 
Symbol
NRAS
Name
(RefSeq) GTPase NRas
  KO
K07828  GTPase NRas
Organism
opi  Ochotona princeps (American pika)
Pathway
opi01521  EGFR tyrosine kinase inhibitor resistance
opi01522  Endocrine resistance
opi04010  MAPK signaling pathway
opi04012  ErbB signaling pathway
opi04014  Ras signaling pathway
opi04015  Rap1 signaling pathway
opi04062  Chemokine signaling pathway
opi04068  FoxO signaling pathway
opi04071  Sphingolipid signaling pathway
opi04072  Phospholipase D signaling pathway
opi04137  Mitophagy - animal
opi04140  Autophagy - animal
opi04150  mTOR signaling pathway
opi04151  PI3K-Akt signaling pathway
opi04210  Apoptosis
opi04211  Longevity regulating pathway
opi04213  Longevity regulating pathway - multiple species
opi04218  Cellular senescence
opi04360  Axon guidance
opi04370  VEGF signaling pathway
opi04371  Apelin signaling pathway
opi04540  Gap junction
opi04550  Signaling pathways regulating pluripotency of stem cells
opi04625  C-type lectin receptor signaling pathway
opi04650  Natural killer cell mediated cytotoxicity
opi04660  T cell receptor signaling pathway
opi04662  B cell receptor signaling pathway
opi04664  Fc epsilon RI signaling pathway
opi04714  Thermogenesis
opi04720  Long-term potentiation
opi04722  Neurotrophin signaling pathway
opi04725  Cholinergic synapse
opi04726  Serotonergic synapse
opi04730  Long-term depression
opi04810  Regulation of actin cytoskeleton
opi04910  Insulin signaling pathway
opi04912  GnRH signaling pathway
opi04915  Estrogen signaling pathway
opi04916  Melanogenesis
opi04917  Prolactin signaling pathway
opi04919  Thyroid hormone signaling pathway
opi04921  Oxytocin signaling pathway
opi04926  Relaxin signaling pathway
opi04929  GnRH secretion
opi04933  AGE-RAGE signaling pathway in diabetic complications
opi04935  Growth hormone synthesis, secretion and action
opi05010  Alzheimer disease
opi05022  Pathways of neurodegeneration - multiple diseases
opi05034  Alcoholism
opi05160  Hepatitis C
opi05161  Hepatitis B
opi05163  Human cytomegalovirus infection
opi05165  Human papillomavirus infection
opi05166  Human T-cell leukemia virus 1 infection
opi05167  Kaposi sarcoma-associated herpesvirus infection
opi05170  Human immunodeficiency virus 1 infection
opi05200  Pathways in cancer
opi05203  Viral carcinogenesis
opi05205  Proteoglycans in cancer
opi05206  MicroRNAs in cancer
opi05207  Chemical carcinogenesis - receptor activation
opi05208  Chemical carcinogenesis - reactive oxygen species
opi05210  Colorectal cancer
opi05211  Renal cell carcinoma
opi05213  Endometrial cancer
opi05214  Glioma
opi05215  Prostate cancer
opi05216  Thyroid cancer
opi05218  Melanoma
opi05219  Bladder cancer
opi05220  Chronic myeloid leukemia
opi05221  Acute myeloid leukemia
opi05223  Non-small cell lung cancer
opi05224  Breast cancer
opi05225  Hepatocellular carcinoma
opi05226  Gastric cancer
opi05230  Central carbon metabolism in cancer
opi05231  Choline metabolism in cancer
opi05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
opi05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:opi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101524465 (NRAS)
   04012 ErbB signaling pathway
    101524465 (NRAS)
   04014 Ras signaling pathway
    101524465 (NRAS)
   04015 Rap1 signaling pathway
    101524465 (NRAS)
   04370 VEGF signaling pathway
    101524465 (NRAS)
   04371 Apelin signaling pathway
    101524465 (NRAS)
   04068 FoxO signaling pathway
    101524465 (NRAS)
   04072 Phospholipase D signaling pathway
    101524465 (NRAS)
   04071 Sphingolipid signaling pathway
    101524465 (NRAS)
   04151 PI3K-Akt signaling pathway
    101524465 (NRAS)
   04150 mTOR signaling pathway
    101524465 (NRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101524465 (NRAS)
   04137 Mitophagy - animal
    101524465 (NRAS)
  09143 Cell growth and death
   04210 Apoptosis
    101524465 (NRAS)
   04218 Cellular senescence
    101524465 (NRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101524465 (NRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    101524465 (NRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101524465 (NRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    101524465 (NRAS)
   04650 Natural killer cell mediated cytotoxicity
    101524465 (NRAS)
   04660 T cell receptor signaling pathway
    101524465 (NRAS)
   04662 B cell receptor signaling pathway
    101524465 (NRAS)
   04664 Fc epsilon RI signaling pathway
    101524465 (NRAS)
   04062 Chemokine signaling pathway
    101524465 (NRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101524465 (NRAS)
   04929 GnRH secretion
    101524465 (NRAS)
   04912 GnRH signaling pathway
    101524465 (NRAS)
   04915 Estrogen signaling pathway
    101524465 (NRAS)
   04917 Prolactin signaling pathway
    101524465 (NRAS)
   04921 Oxytocin signaling pathway
    101524465 (NRAS)
   04926 Relaxin signaling pathway
    101524465 (NRAS)
   04935 Growth hormone synthesis, secretion and action
    101524465 (NRAS)
   04919 Thyroid hormone signaling pathway
    101524465 (NRAS)
   04916 Melanogenesis
    101524465 (NRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    101524465 (NRAS)
   04726 Serotonergic synapse
    101524465 (NRAS)
   04720 Long-term potentiation
    101524465 (NRAS)
   04730 Long-term depression
    101524465 (NRAS)
   04722 Neurotrophin signaling pathway
    101524465 (NRAS)
  09158 Development and regeneration
   04360 Axon guidance
    101524465 (NRAS)
  09149 Aging
   04211 Longevity regulating pathway
    101524465 (NRAS)
   04213 Longevity regulating pathway - multiple species
    101524465 (NRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    101524465 (NRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101524465 (NRAS)
   05206 MicroRNAs in cancer
    101524465 (NRAS)
   05205 Proteoglycans in cancer
    101524465 (NRAS)
   05207 Chemical carcinogenesis - receptor activation
    101524465 (NRAS)
   05208 Chemical carcinogenesis - reactive oxygen species
    101524465 (NRAS)
   05203 Viral carcinogenesis
    101524465 (NRAS)
   05230 Central carbon metabolism in cancer
    101524465 (NRAS)
   05231 Choline metabolism in cancer
    101524465 (NRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101524465 (NRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101524465 (NRAS)
   05225 Hepatocellular carcinoma
    101524465 (NRAS)
   05226 Gastric cancer
    101524465 (NRAS)
   05214 Glioma
    101524465 (NRAS)
   05216 Thyroid cancer
    101524465 (NRAS)
   05221 Acute myeloid leukemia
    101524465 (NRAS)
   05220 Chronic myeloid leukemia
    101524465 (NRAS)
   05218 Melanoma
    101524465 (NRAS)
   05211 Renal cell carcinoma
    101524465 (NRAS)
   05219 Bladder cancer
    101524465 (NRAS)
   05215 Prostate cancer
    101524465 (NRAS)
   05213 Endometrial cancer
    101524465 (NRAS)
   05224 Breast cancer
    101524465 (NRAS)
   05223 Non-small cell lung cancer
    101524465 (NRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101524465 (NRAS)
   05170 Human immunodeficiency virus 1 infection
    101524465 (NRAS)
   05161 Hepatitis B
    101524465 (NRAS)
   05160 Hepatitis C
    101524465 (NRAS)
   05163 Human cytomegalovirus infection
    101524465 (NRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101524465 (NRAS)
   05165 Human papillomavirus infection
    101524465 (NRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101524465 (NRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    101524465 (NRAS)
  09165 Substance dependence
   05034 Alcoholism
    101524465 (NRAS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101524465 (NRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101524465 (NRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101524465 (NRAS)
   01522 Endocrine resistance
    101524465 (NRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:opi04131]
    101524465 (NRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:opi04147]
    101524465 (NRAS)
   04031 GTP-binding proteins [BR:opi04031]
    101524465 (NRAS)
Membrane trafficking [BR:opi04131]
 Exocytosis
  Small GTPases and associated proteins
   Other small GTPases and associated proteins
    101524465 (NRAS)
 Endocytosis
  Macropinocytosis
   Ras GTPases
    101524465 (NRAS)
Exosome [BR:opi04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101524465 (NRAS)
  Exosomal proteins of other body fluids (saliva and urine)
   101524465 (NRAS)
  Exosomal proteins of breast cancer cells
   101524465 (NRAS)
  Exosomal proteins of colorectal cancer cells
   101524465 (NRAS)
GTP-binding proteins [BR:opi04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    101524465 (NRAS)
SSDB
Motif
Pfam: Ras Roc RsgA_GTPase Arf GTP_EFTU FeoB_N AAA_14 Septin nSTAND3 ParA NB-ARC Aldo_ket_red AAA_16 ATPase_2 Viral_helicase1 MMR_HSR1 Ldh_1_N
Other DBs
NCBI-GeneID: 101524465
NCBI-ProteinID: XP_004582194
LinkDB
Position
13:complement(102338254..102348452)
AA seq 132 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEVQWEQIKRVKDSDDVPMVLVGNK
CDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDG
TQGCMGLPCVVM
NT seq 399 nt   +upstreamnt  +downstreamnt
atgaccgagtacaaactggtggtggttggagcaggtggtgttgggaaaagcgcactgaca
atccagctaatccagaaccactttgtggatgaatatgatcctaccatagaggttcaatgg
gaacagattaagcgagtgaaagattcagatgatgtacctatggtgctggtaggaaacaag
tgtgacttgccaacaaggacggttgacacaaaacaagcccatgaactggccaagagttac
gggattccgttcattgaaacctcagccaagaccagacagggtgttgaagatgccttttac
acactggtaagagaaatacgccagtaccgaatgaaaaagctcaacagcagtgatgatgga
actcaaggttgtatggggttgccctgtgtggtgatgtaa

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