KEGG   Ochotona princeps (American pika): 101525120
Entry
101525120         CDS       T07609                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
opi  Ochotona princeps (American pika)
Pathway
opi01522  Endocrine resistance
opi04010  MAPK signaling pathway
opi04015  Rap1 signaling pathway
opi04068  FoxO signaling pathway
opi04071  Sphingolipid signaling pathway
opi04114  Oocyte meiosis
opi04148  Efferocytosis
opi04218  Cellular senescence
opi04261  Adrenergic signaling in cardiomyocytes
opi04370  VEGF signaling pathway
opi04380  Osteoclast differentiation
opi04517  IgSF CAM signaling
opi04550  Signaling pathways regulating pluripotency of stem cells
opi04611  Platelet activation
opi04613  Neutrophil extracellular trap formation
opi04620  Toll-like receptor signaling pathway
opi04621  NOD-like receptor signaling pathway
opi04622  RIG-I-like receptor signaling pathway
opi04625  C-type lectin receptor signaling pathway
opi04657  IL-17 signaling pathway
opi04658  Th1 and Th2 cell differentiation
opi04659  Th17 cell differentiation
opi04660  T cell receptor signaling pathway
opi04664  Fc epsilon RI signaling pathway
opi04668  TNF signaling pathway
opi04670  Leukocyte transendothelial migration
opi04714  Thermogenesis
opi04722  Neurotrophin signaling pathway
opi04723  Retrograde endocannabinoid signaling
opi04728  Dopaminergic synapse
opi04750  Inflammatory mediator regulation of TRP channels
opi04912  GnRH signaling pathway
opi04914  Progesterone-mediated oocyte maturation
opi04917  Prolactin signaling pathway
opi04926  Relaxin signaling pathway
opi04932  Non-alcoholic fatty liver disease
opi04933  AGE-RAGE signaling pathway in diabetic complications
opi04935  Growth hormone synthesis, secretion and action
opi04936  Alcoholic liver disease
opi05014  Amyotrophic lateral sclerosis
opi05020  Prion disease
opi05022  Pathways of neurodegeneration - multiple diseases
opi05132  Salmonella infection
opi05133  Pertussis
opi05135  Yersinia infection
opi05140  Leishmaniasis
opi05142  Chagas disease
opi05145  Toxoplasmosis
opi05152  Tuberculosis
opi05161  Hepatitis B
opi05163  Human cytomegalovirus infection
opi05167  Kaposi sarcoma-associated herpesvirus infection
opi05169  Epstein-Barr virus infection
opi05170  Human immunodeficiency virus 1 infection
opi05171  Coronavirus disease - COVID-19
opi05205  Proteoglycans in cancer
opi05208  Chemical carcinogenesis - reactive oxygen species
opi05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
opi05415  Diabetic cardiomyopathy
opi05417  Lipid and atherosclerosis
opi05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:opi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101525120 (MAPK14)
   04015 Rap1 signaling pathway
    101525120 (MAPK14)
   04370 VEGF signaling pathway
    101525120 (MAPK14)
   04668 TNF signaling pathway
    101525120 (MAPK14)
   04068 FoxO signaling pathway
    101525120 (MAPK14)
   04071 Sphingolipid signaling pathway
    101525120 (MAPK14)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    101525120 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101525120 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    101525120 (MAPK14)
   04218 Cellular senescence
    101525120 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101525120 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101525120 (MAPK14)
   04613 Neutrophil extracellular trap formation
    101525120 (MAPK14)
   04620 Toll-like receptor signaling pathway
    101525120 (MAPK14)
   04621 NOD-like receptor signaling pathway
    101525120 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    101525120 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    101525120 (MAPK14)
   04660 T cell receptor signaling pathway
    101525120 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    101525120 (MAPK14)
   04659 Th17 cell differentiation
    101525120 (MAPK14)
   04657 IL-17 signaling pathway
    101525120 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    101525120 (MAPK14)
   04670 Leukocyte transendothelial migration
    101525120 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101525120 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    101525120 (MAPK14)
   04917 Prolactin signaling pathway
    101525120 (MAPK14)
   04926 Relaxin signaling pathway
    101525120 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    101525120 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101525120 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    101525120 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    101525120 (MAPK14)
   04722 Neurotrophin signaling pathway
    101525120 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101525120 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101525120 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    101525120 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101525120 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    101525120 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101525120 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101525120 (MAPK14)
   05161 Hepatitis B
    101525120 (MAPK14)
   05171 Coronavirus disease - COVID-19
    101525120 (MAPK14)
   05163 Human cytomegalovirus infection
    101525120 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101525120 (MAPK14)
   05169 Epstein-Barr virus infection
    101525120 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101525120 (MAPK14)
   05135 Yersinia infection
    101525120 (MAPK14)
   05133 Pertussis
    101525120 (MAPK14)
   05152 Tuberculosis
    101525120 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101525120 (MAPK14)
   05140 Leishmaniasis
    101525120 (MAPK14)
   05142 Chagas disease
    101525120 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101525120 (MAPK14)
   05020 Prion disease
    101525120 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    101525120 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101525120 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    101525120 (MAPK14)
   05415 Diabetic cardiomyopathy
    101525120 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101525120 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    101525120 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101525120 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101525120 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:opi01001]
    101525120 (MAPK14)
Enzymes [BR:opi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101525120 (MAPK14)
Protein kinases [BR:opi01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101525120 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH
Other DBs
NCBI-GeneID: 101525120
NCBI-ProteinID: XP_004590373
LinkDB
Position
12:33943881..34022791
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKIGLRVAVKKLSRPFQ
SIIHAKRTYREVRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIILNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAEVLKKISSESARNYIQSLNQMPKMNFANVFLGANPLAVDLLEKMLVLDSDKRITAA
QALAHDYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYNEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctcaacaagaccatctgggaggtg
cccgagcgctaccagaacctgtcccctgtgggctctggcgcctatggctcggtgtgtgct
gctttcgacacaaaaattgggttgcgcgtggcggtgaagaagctctcccgaccgtttcag
tccatcatccacgccaaaaggacctacagggaggtgcggctgctcaaacacatgaaacat
gagaatgtgattggtcttttggatgttttcacacctgcaaggtctctggaggagttcaat
gatgtgtatctggtgacccatcttatgggggcagatctgaacaacattgtaaaatgccag
aagctcacagatgaccacgtccagttccttatctaccagattctccgaggcctaaagtat
atacattcagcagacattattcacagggacctaaagcccagtaaccttgctgtgaacgaa
gactgtgagctgaagatcctggattttggattggctcgacatactgatgatgaaatgaca
ggctacgttgccaccaggtggtatcgggctcctgagatcatactgaactggatgcactac
aaccagacagttgacatttggtcggtcggatgcatcatggcggagctgctgactggaaga
acgttgtttccaggaacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgaggttttgaagaaaatctcctcagagtctgcaaggaactacattcag
tctttgaaccagatgccaaagatgaactttgcaaacgtatttcttggtgccaatcccctg
gccgttgacttgctggagaagatgctggttttggactcagataagagaatcactgcagcc
caagccctcgctcatgactactttgctcagtaccacgatcctgacgacgaaccagtggcc
gacccttacgatcagtcttttgaaagcagagacctcctcatcgatgagtggaaaagcctg
acatataatgaagtcatcagctttgtgccaccgccccttgaccaagaagagatggaatcc
tga

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