Ochotona princeps (American pika): 101525427
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Entry
101525427 CDS
T07609
Name
(RefSeq) mitogen-activated protein kinase 1
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi01521
EGFR tyrosine kinase inhibitor resistance
opi01522
Endocrine resistance
opi01524
Platinum drug resistance
opi04010
MAPK signaling pathway
opi04012
ErbB signaling pathway
opi04014
Ras signaling pathway
opi04015
Rap1 signaling pathway
opi04022
cGMP-PKG signaling pathway
opi04024
cAMP signaling pathway
opi04062
Chemokine signaling pathway
opi04066
HIF-1 signaling pathway
opi04068
FoxO signaling pathway
opi04071
Sphingolipid signaling pathway
opi04072
Phospholipase D signaling pathway
opi04114
Oocyte meiosis
opi04140
Autophagy - animal
opi04148
Efferocytosis
opi04150
mTOR signaling pathway
opi04151
PI3K-Akt signaling pathway
opi04210
Apoptosis
opi04218
Cellular senescence
opi04261
Adrenergic signaling in cardiomyocytes
opi04270
Vascular smooth muscle contraction
opi04350
TGF-beta signaling pathway
opi04360
Axon guidance
opi04370
VEGF signaling pathway
opi04371
Apelin signaling pathway
opi04380
Osteoclast differentiation
opi04510
Focal adhesion
opi04520
Adherens junction
opi04540
Gap junction
opi04550
Signaling pathways regulating pluripotency of stem cells
opi04611
Platelet activation
opi04613
Neutrophil extracellular trap formation
opi04620
Toll-like receptor signaling pathway
opi04621
NOD-like receptor signaling pathway
opi04625
C-type lectin receptor signaling pathway
opi04650
Natural killer cell mediated cytotoxicity
opi04657
IL-17 signaling pathway
opi04658
Th1 and Th2 cell differentiation
opi04659
Th17 cell differentiation
opi04660
T cell receptor signaling pathway
opi04662
B cell receptor signaling pathway
opi04664
Fc epsilon RI signaling pathway
opi04666
Fc gamma R-mediated phagocytosis
opi04668
TNF signaling pathway
opi04713
Circadian entrainment
opi04720
Long-term potentiation
opi04722
Neurotrophin signaling pathway
opi04723
Retrograde endocannabinoid signaling
opi04724
Glutamatergic synapse
opi04725
Cholinergic synapse
opi04726
Serotonergic synapse
opi04730
Long-term depression
opi04810
Regulation of actin cytoskeleton
opi04910
Insulin signaling pathway
opi04912
GnRH signaling pathway
opi04914
Progesterone-mediated oocyte maturation
opi04915
Estrogen signaling pathway
opi04916
Melanogenesis
opi04917
Prolactin signaling pathway
opi04919
Thyroid hormone signaling pathway
opi04921
Oxytocin signaling pathway
opi04926
Relaxin signaling pathway
opi04928
Parathyroid hormone synthesis, secretion and action
opi04929
GnRH secretion
opi04930
Type II diabetes mellitus
opi04933
AGE-RAGE signaling pathway in diabetic complications
opi04934
Cushing syndrome
opi04935
Growth hormone synthesis, secretion and action
opi04960
Aldosterone-regulated sodium reabsorption
opi05010
Alzheimer disease
opi05020
Prion disease
opi05022
Pathways of neurodegeneration - multiple diseases
opi05034
Alcoholism
opi05132
Salmonella infection
opi05133
Pertussis
opi05135
Yersinia infection
opi05140
Leishmaniasis
opi05142
Chagas disease
opi05145
Toxoplasmosis
opi05152
Tuberculosis
opi05160
Hepatitis C
opi05161
Hepatitis B
opi05163
Human cytomegalovirus infection
opi05164
Influenza A
opi05165
Human papillomavirus infection
opi05166
Human T-cell leukemia virus 1 infection
opi05167
Kaposi sarcoma-associated herpesvirus infection
opi05170
Human immunodeficiency virus 1 infection
opi05171
Coronavirus disease - COVID-19
opi05200
Pathways in cancer
opi05203
Viral carcinogenesis
opi05205
Proteoglycans in cancer
opi05206
MicroRNAs in cancer
opi05207
Chemical carcinogenesis - receptor activation
opi05208
Chemical carcinogenesis - reactive oxygen species
opi05210
Colorectal cancer
opi05211
Renal cell carcinoma
opi05212
Pancreatic cancer
opi05213
Endometrial cancer
opi05214
Glioma
opi05215
Prostate cancer
opi05216
Thyroid cancer
opi05218
Melanoma
opi05219
Bladder cancer
opi05220
Chronic myeloid leukemia
opi05221
Acute myeloid leukemia
opi05223
Non-small cell lung cancer
opi05224
Breast cancer
opi05225
Hepatocellular carcinoma
opi05226
Gastric cancer
opi05230
Central carbon metabolism in cancer
opi05231
Choline metabolism in cancer
opi05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
opi05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101525427
04012 ErbB signaling pathway
101525427
04014 Ras signaling pathway
101525427
04015 Rap1 signaling pathway
101525427
04350 TGF-beta signaling pathway
101525427
04370 VEGF signaling pathway
101525427
04371 Apelin signaling pathway
101525427
04668 TNF signaling pathway
101525427
04066 HIF-1 signaling pathway
101525427
04068 FoxO signaling pathway
101525427
04072 Phospholipase D signaling pathway
101525427
04071 Sphingolipid signaling pathway
101525427
04024 cAMP signaling pathway
101525427
04022 cGMP-PKG signaling pathway
101525427
04151 PI3K-Akt signaling pathway
101525427
04150 mTOR signaling pathway
101525427
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101525427
04148 Efferocytosis
101525427
09143 Cell growth and death
04114 Oocyte meiosis
101525427
04210 Apoptosis
101525427
04218 Cellular senescence
101525427
09144 Cellular community - eukaryotes
04510 Focal adhesion
101525427
04520 Adherens junction
101525427
04540 Gap junction
101525427
04550 Signaling pathways regulating pluripotency of stem cells
101525427
09142 Cell motility
04810 Regulation of actin cytoskeleton
101525427
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101525427
04613 Neutrophil extracellular trap formation
101525427
04620 Toll-like receptor signaling pathway
101525427
04621 NOD-like receptor signaling pathway
101525427
04625 C-type lectin receptor signaling pathway
101525427
04650 Natural killer cell mediated cytotoxicity
101525427
04660 T cell receptor signaling pathway
101525427
04658 Th1 and Th2 cell differentiation
101525427
04659 Th17 cell differentiation
101525427
04657 IL-17 signaling pathway
101525427
04662 B cell receptor signaling pathway
101525427
04664 Fc epsilon RI signaling pathway
101525427
04666 Fc gamma R-mediated phagocytosis
101525427
04062 Chemokine signaling pathway
101525427
09152 Endocrine system
04910 Insulin signaling pathway
101525427
04929 GnRH secretion
101525427
04912 GnRH signaling pathway
101525427
04915 Estrogen signaling pathway
101525427
04914 Progesterone-mediated oocyte maturation
101525427
04917 Prolactin signaling pathway
101525427
04921 Oxytocin signaling pathway
101525427
04926 Relaxin signaling pathway
101525427
04935 Growth hormone synthesis, secretion and action
101525427
04919 Thyroid hormone signaling pathway
101525427
04928 Parathyroid hormone synthesis, secretion and action
101525427
04916 Melanogenesis
101525427
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
101525427
04270 Vascular smooth muscle contraction
101525427
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
101525427
09156 Nervous system
04724 Glutamatergic synapse
101525427
04725 Cholinergic synapse
101525427
04726 Serotonergic synapse
101525427
04720 Long-term potentiation
101525427
04730 Long-term depression
101525427
04723 Retrograde endocannabinoid signaling
101525427
04722 Neurotrophin signaling pathway
101525427
09158 Development and regeneration
04360 Axon guidance
101525427
04380 Osteoclast differentiation
101525427
09159 Environmental adaptation
04713 Circadian entrainment
101525427
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101525427
05206 MicroRNAs in cancer
101525427
05205 Proteoglycans in cancer
101525427
05207 Chemical carcinogenesis - receptor activation
101525427
05208 Chemical carcinogenesis - reactive oxygen species
101525427
05203 Viral carcinogenesis
101525427
05230 Central carbon metabolism in cancer
101525427
05231 Choline metabolism in cancer
101525427
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101525427
09162 Cancer: specific types
05210 Colorectal cancer
101525427
05212 Pancreatic cancer
101525427
05225 Hepatocellular carcinoma
101525427
05226 Gastric cancer
101525427
05214 Glioma
101525427
05216 Thyroid cancer
101525427
05221 Acute myeloid leukemia
101525427
05220 Chronic myeloid leukemia
101525427
05218 Melanoma
101525427
05211 Renal cell carcinoma
101525427
05219 Bladder cancer
101525427
05215 Prostate cancer
101525427
05213 Endometrial cancer
101525427
05224 Breast cancer
101525427
05223 Non-small cell lung cancer
101525427
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101525427
05170 Human immunodeficiency virus 1 infection
101525427
05161 Hepatitis B
101525427
05160 Hepatitis C
101525427
05171 Coronavirus disease - COVID-19
101525427
05164 Influenza A
101525427
05163 Human cytomegalovirus infection
101525427
05167 Kaposi sarcoma-associated herpesvirus infection
101525427
05165 Human papillomavirus infection
101525427
09171 Infectious disease: bacterial
05132 Salmonella infection
101525427
05135 Yersinia infection
101525427
05133 Pertussis
101525427
05152 Tuberculosis
101525427
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101525427
05140 Leishmaniasis
101525427
05142 Chagas disease
101525427
09164 Neurodegenerative disease
05010 Alzheimer disease
101525427
05020 Prion disease
101525427
05022 Pathways of neurodegeneration - multiple diseases
101525427
09165 Substance dependence
05034 Alcoholism
101525427
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101525427
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
101525427
04933 AGE-RAGE signaling pathway in diabetic complications
101525427
04934 Cushing syndrome
101525427
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101525427
01524 Platinum drug resistance
101525427
01522 Endocrine resistance
101525427
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
opi01001
]
101525427
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
opi03036
]
101525427
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
opi04147
]
101525427
Enzymes [BR:
opi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
101525427
Protein kinases [BR:
opi01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
101525427
Chromosome and associated proteins [BR:
opi03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
101525427
Exosome [BR:
opi04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
101525427
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Motif
Other DBs
NCBI-GeneID:
101525427
NCBI-ProteinID:
XP_004585794
LinkDB
All DBs
Position
4A:21396113..21397195
Genome browser
AA seq
359 aa
AA seq
DB search
MAVAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCFAYDNVNKVRVAIKKISPFEH
QTYCQRTLREIKILLRFRHEHIIGISDIIRAPTIEPMKDVYIVQDLMETDLYKLLKTQHL
SNDHICYFLYQILQGLKYIHSANVLHRDLKPSNLLLNTTCDLKICEFGLARVADPDHDHT
GFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHIL
GILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKR
IEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
NT seq
1080 nt
NT seq
+upstream
nt +downstream
nt
atggcggtggcggcggcgggcgcgggcccggagatggtccgcgggcaggtgttcgacgtg
gggccgcgctacaccaacctctcgtacatcggcgagggtgcctacggcatggtgtgcttt
gcttatgataacgtcaacaaagttcgagtggctatcaagaaaatcagtccttttgagcac
cagacctattgccagaggaccctgagggagatcaagatcttgctgcgtttcagacatgaa
catatcattgggatcagtgacatcatccgcgcaccgaccatcgagccgatgaaagatgta
tacatagtacaggacctaatggagacagatctctacaagctcttgaagacacagcacctc
agcaacgaccatatctgctattttctttaccagatcctgcaaggattaaaatacattcac
tcagctaacgttctgcaccgcgacctcaagccttccaacctgctgctcaacaccacctgt
gatctcaagatctgtgaatttggcttggcccgcgttgcagatccggaccacgaccacaca
gggttcctgacagagtatgtagccacccgttggtacagggctccagaaattatgttgaat
tccaagggctacaccaagtccatcgacatctggtctgtgggctgcatcctggcggagatg
ctctccaaccggcccatcttcccggggaagcactacctcgaccagctgaaccacattctg
ggtattcttggttccccatcacaagaagacctgaactgtataataaatttaaaagctaga
aactatttgctttctcttccacacaaaaacaaggtgccatggaacaggttgttcccaaat
gccgactccaaagctctggacttgctggacaaaatgttgacattcaaccctcacaagagg
atcgaggtcgaacaggctctggcgcacccctatctggagcaatattatgaccccagtgac
gagcccattgccgaagctccattcaagtttgacatggaattagatgacttgcccaaggaa
aaactcaaggagctcatttttgaagagactgcaagattccagccaggatacagatcttaa
DBGET
integrated database retrieval system