Ochotona princeps (American pika): 101526399
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Entry
101526399 CDS
T07609
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi00562
Inositol phosphate metabolism
opi01100
Metabolic pathways
opi01521
EGFR tyrosine kinase inhibitor resistance
opi04012
ErbB signaling pathway
opi04014
Ras signaling pathway
opi04020
Calcium signaling pathway
opi04062
Chemokine signaling pathway
opi04064
NF-kappa B signaling pathway
opi04066
HIF-1 signaling pathway
opi04070
Phosphatidylinositol signaling system
opi04072
Phospholipase D signaling pathway
opi04360
Axon guidance
opi04370
VEGF signaling pathway
opi04380
Osteoclast differentiation
opi04611
Platelet activation
opi04613
Neutrophil extracellular trap formation
opi04625
C-type lectin receptor signaling pathway
opi04650
Natural killer cell mediated cytotoxicity
opi04662
B cell receptor signaling pathway
opi04664
Fc epsilon RI signaling pathway
opi04666
Fc gamma R-mediated phagocytosis
opi04670
Leukocyte transendothelial migration
opi04722
Neurotrophin signaling pathway
opi04750
Inflammatory mediator regulation of TRP channels
opi04919
Thyroid hormone signaling pathway
opi04933
AGE-RAGE signaling pathway in diabetic complications
opi04935
Growth hormone synthesis, secretion and action
opi05167
Kaposi sarcoma-associated herpesvirus infection
opi05169
Epstein-Barr virus infection
opi05170
Human immunodeficiency virus 1 infection
opi05171
Coronavirus disease - COVID-19
opi05200
Pathways in cancer
opi05205
Proteoglycans in cancer
opi05206
MicroRNAs in cancer
opi05214
Glioma
opi05223
Non-small cell lung cancer
opi05225
Hepatocellular carcinoma
Module
opi_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
101526399 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101526399 (PLCG2)
04014 Ras signaling pathway
101526399 (PLCG2)
04370 VEGF signaling pathway
101526399 (PLCG2)
04064 NF-kappa B signaling pathway
101526399 (PLCG2)
04066 HIF-1 signaling pathway
101526399 (PLCG2)
04020 Calcium signaling pathway
101526399 (PLCG2)
04070 Phosphatidylinositol signaling system
101526399 (PLCG2)
04072 Phospholipase D signaling pathway
101526399 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101526399 (PLCG2)
04613 Neutrophil extracellular trap formation
101526399 (PLCG2)
04625 C-type lectin receptor signaling pathway
101526399 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
101526399 (PLCG2)
04662 B cell receptor signaling pathway
101526399 (PLCG2)
04664 Fc epsilon RI signaling pathway
101526399 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
101526399 (PLCG2)
04670 Leukocyte transendothelial migration
101526399 (PLCG2)
04062 Chemokine signaling pathway
101526399 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
101526399 (PLCG2)
04919 Thyroid hormone signaling pathway
101526399 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
101526399 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101526399 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
101526399 (PLCG2)
04380 Osteoclast differentiation
101526399 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101526399 (PLCG2)
05206 MicroRNAs in cancer
101526399 (PLCG2)
05205 Proteoglycans in cancer
101526399 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101526399 (PLCG2)
05214 Glioma
101526399 (PLCG2)
05223 Non-small cell lung cancer
101526399 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101526399 (PLCG2)
05171 Coronavirus disease - COVID-19
101526399 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
101526399 (PLCG2)
05169 Epstein-Barr virus infection
101526399 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101526399 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101526399 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
opi04131
]
101526399 (PLCG2)
Enzymes [BR:
opi01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
101526399 (PLCG2)
Membrane trafficking [BR:
opi04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
101526399 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
101526399 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
SH3_9
PH
PH_12
EF-hand_PLCG1
SH2_1
PH_14
SH3_2
EF-hand_like
Adhesin_E
GDPD
Motif
Other DBs
NCBI-GeneID:
101526399
NCBI-ProteinID:
XP_004584111
LinkDB
All DBs
Position
5:47313823..47426291
Genome browser
AA seq
1265 aa
AA seq
DB search
MNTMANVEALPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEDCCFTVLYGTQFVLNTLSLAADSKEDAT
KWLSGLKILHQEAMRASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSSA
KFLKDKFVEIGTHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDVVDIQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKV
FKEVLGNLLLTKPTEASADQLPSPNQLRDKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTVEEEPPQDTPPTELHFGEKWFHKKVEKR
MSAEKLLQEYCAETGGKDGTFLVRESETYPDKYTLSFWRSGRVQHCLIRSTVEGGTKKYY
LTDNLKFTSVYALIQHYREAHLRCAEFELQLTDPVPNPNPHESKPWFYGALSRGEAEDML
MRIPRDGAFLIRRREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHTLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKQSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTFDVEEMEKQII
EDNPLGALCRGILDLNTYNIVKIPQGKNQKQFVFILEPKKQGDPPVEFATDRVEELFEWF
QSIREITWKIDTKENNLRYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSIVRQKPIDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKY
MQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTVTVKVLGARHLPKLCRSI
ACPFVEVEICGAECDNNKFKTTVVNDNGLNPVWASTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKGIKSGYRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALIKEFNVNENQLQMYQEKCNRRLREKRVSN
SKFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgaacaccatggcaaacgtggaggcccttccggagtatgagaagagccagatcaagaga
gctctggagctgggcacggtgatgacagtgttcagcttccgcaagtccacaccagagcgg
aggactgtccaggtgatcatggagacccgccaagtggcctggagcaagacggctgacaaa
attgagggcttcttggacatcatggagatcaaggaaatccgcccagggaagaactcgaag
gattttgagcgtgccaaagcagtgcgccagaaggaagactgctgctttaccgtcttgtac
ggcactcagtttgtcctcaacaccctcagcttggcagccgactccaaagaggatgcaacc
aagtggctttcaggcctgaaaatcttgcaccaagaggcaatgcgtgcatccacgcccacc
atcattgagagctggctgaggaagcagatttattccgtggatcaaaccagaagaaacagc
atcagcctccgggagctgaaaaccatcctcccactggtcaacttcaaagtgagcagtgcc
aagttcctcaaagacaagtttgtggaaataggcacacacaaagatgagctcagcttcgag
cagttccatctcttctataaaaagctgatgtttgagcagcagaaatcgatccttgatgag
ttcaagaaggattcctccgttttcatcctggggaacacagaccggcctgacgcctctgcg
gtccacctgcatgacttccagcgctttctcttgcatgagcagcaggagcactgggcccaa
gacctgaacaaggtgcgtgagcggatgaccaagttcattgacgatacgatgagggagaca
gctgagcccttcttgttcgtggacgagttcctcacgtacctgttctcgcgagaaaacagc
atctgggatgagaagtacgacgtggtggacatacaggatatgaacaaccccttgtctcac
tactggatctcctcgtcccacaacacgtacctcactggggaccagctgcggagcgagtca
tccacagaagcctacatccgctgcctgcgcatgggctgccgctgcatcgaactggactgt
tgggacggacccgacggaaaacccatcatctaccatggctggacgcggaccaccaagatc
aagttcgacgacgtcgtgcaggccatcaaagaccatgcatttgtcacgtccagcttcccg
gtgatcctgtccatcgaggagcactgcagtgtggagcagcagcgccacatggccaaggtg
ttcaaggaggtactgggcaacctgctactcaccaagcctacggaggccagcgctgaccag
ctgccctcgcccaaccagcttcgggacaagatcatcatcaagcataagaagctgggtccc
cggggtgacgtggacgtcaacatggaggacaagaaggacgagcacaagcagcagggtgaa
ctgtacatgtgggactccattgaccagaagtggactcgccactactgtgccatcgctgac
gccaagctgtccttcagtgatgacattgagcagactgtggaggaagagccgccccaggat
acgccccccacggagctgcattttggggagaaatggtttcacaagaaggtggagaagagg
atgagtgcggagaagctgctgcaggagtactgcgccgagacgggtggcaaggacggcacg
ttcctggtgcgcgagagcgagacctaccccgacaagtacacgctgtccttctggcgatcg
ggccgcgtgcagcactgcctgatccgctccaccgtggagggcggcactaagaagtactat
ctgactgacaacctcaagttcaccagcgtctacgcgctcatccagcactaccgtgaggca
cacctgcgctgtgccgagttcgagctgcagctcaccgaccccgtgcccaaccctaacccg
catgagtcgaagccgtggttctatggtgcgctgagccgtggggaagccgaggacatgctc
atgaggatcccgcgggacggcgccttcctgatccgccggcgggagggcagcgactcctac
gccatcaccttcagggccaggggcaaggtgaagcattgtcgtatcaaccgcgatggccga
cacttcgtgctggggacctctgcctacttcgagagcctcgtggagctcgtcagctactac
gagaagcacacgctgtaccgcaagatgaggctgcgctaccctgtgacccctgagctgctg
gagcgctacaacatggaaagagacatcaactccctttatgatgtcagcaggatgtacgtg
gatccgagtgagatcaacccctccatgccgcagagaaccgtgaaggctctgtacgactac
aaagccaagcagagtgatgagctgagcttctgccgcggtgccctcatccacaatgtctcc
aaggagcctgggggctggtggaagggggattacgggacgcggatccagcagtacttcccg
tccaactatgtcgaggacatctccacatttgatgtggaggagatggaaaagcagattatt
gaagacaatcccttaggcgcgctctgcagaggaatcctggacctcaatacctataacatc
gtgaaaatcccacagggcaaaaaccagaagcaattcgtgtttatcctggagcccaaaaag
cagggtgatcccccggtggagttcgccacagacagggtggaagagctcttcgagtggttt
cagagcattcgggagatcacctggaagatcgacaccaaggagaacaacctgcggtactgg
gagaagaaccagtccattgccatcgagctctccgacttggtcgtctattgcaagccgacc
agcaagaccaaggacaacctagaaaaccctgatttccgggaaatccgctccttcgtcgag
acaaaggctgacagcatcgtgcggcagaagcccatcgaccttctgcggtacaaccagaag
ggcctgacccgcgtctaccccaagggccagcgggttgactcctccaactatgaccccttc
cgcctgtggctctgcggctcccagatggtggcgctcaacttccagactgcagacaagtac
atgcagatgaatcacgccttgttttcactcaacgggcggacaggctatgtcctacagcct
gagagcatgcggactgagaagtacgacccgatgcccccagagtcgcagaggaagatcctg
atgacggtcactgtcaaggtcctgggtgcccgccatctccccaagctgtgccgcagcatt
gcctgtcccttcgtggaagtggaaatctgcggagccgaatgtgacaacaacaagtttaag
actacggtcgtaaatgataatggcctcaacccagtctgggcttccacccaggagaaggtg
acatttgagatttatgaccccaacttggcatttctgcgcttcgtggtttatgaggaagat
atgttcagtgaccccaacttccttgctcatgccacctaccccattaaaggcatcaagtca
ggctacagatctgtccctctgaagaatgggtacagtgaggacattgagctggcttctctc
ctggttttctgtgagatgcgaccagtcctggagagtgaggaggaactttactcctcctgt
cgccagctgcggaggcggcaagaagaactgaacaaccaactcttcctgtatgacacacac
cagaacttgcgcaatgccaaccgcgatgccctcattaaggagttcaatgtcaatgagaac
cagctccagatgtaccaggagaaatgcaaccggaggttacgagagaaacgagtcagcaac
agcaagttttactcatag
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integrated database retrieval system
