Ochotona princeps (American pika): 101526751
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Entry
101526751 CDS
T07609
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi04140
Autophagy - animal
opi04141
Protein processing in endoplasmic reticulum
opi04210
Apoptosis
opi04932
Non-alcoholic fatty liver disease
opi05010
Alzheimer disease
opi05012
Parkinson disease
opi05014
Amyotrophic lateral sclerosis
opi05016
Huntington disease
opi05017
Spinocerebellar ataxia
opi05022
Pathways of neurodegeneration - multiple diseases
opi05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101526751 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101526751 (ERN1)
09143 Cell growth and death
04210 Apoptosis
101526751 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101526751 (ERN1)
05012 Parkinson disease
101526751 (ERN1)
05014 Amyotrophic lateral sclerosis
101526751 (ERN1)
05016 Huntington disease
101526751 (ERN1)
05017 Spinocerebellar ataxia
101526751 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
101526751 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101526751 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101526751 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
opi01001
]
101526751 (ERN1)
Enzymes [BR:
opi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101526751 (ERN1)
Protein kinases [BR:
opi01001
]
Serine/threonine kinases: Other
IRE family
101526751 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
101526751
NCBI-ProteinID:
XP_004593037
LinkDB
All DBs
Position
19:complement(35643534..35738193)
Genome browser
AA seq
976 aa
AA seq
DB search
MPARRRLLLFLALLLPSPGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKED
PVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMG
KKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATY
FDYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYGSPVVAFYVWQREGLRK
VMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSM
VHEGVAVVPRGSTLPLLEGPKTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLRNYW
LLIGHHETPLSASTKMLERFPNNLPKHRENVIPAESEKKSFEEVINLVDQTSKNTPSTVS
QDVEEKLARAPAKAEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSMHQQRRLQHQQF
QKELEKIQLLQQQQLPFQPPGDATQDTELLDTSSRYSESSGTSSPNTSPRASNHSLHSGS
SASRAGASPSLEPDDDDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRI
LPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFFHL
GLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVG
RHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQR
QANILLGAYNLDCFHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQF
FQDVSDRIEKESLDGPIVRQLEKGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSIRDLL
RAMRNKKHHYRELPVEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMELCSQERLFQPYY
CHEPLEPQPPMTPDAL
NT seq
2931 nt
NT seq
+upstream
nt +downstream
nt
atgccggcgcggcggcggctgctgctgttcctggcgctgctgctgcccagccctgggata
tttggaagtaccagcacagtgacacttcctgaaacgttgttgtttgtctcgaccctggat
ggaagtttgcatgctgtcagcaagaggacaggctcgatcaagtggactttaaaggaagat
ccagtccttcaggtcccaacacatgtggaagagcctgcattcctcccagatcctaatgat
ggcagcctgtatacacttggaggcaagaataacgaaggcctgaccaaacttccctttacc
atcccggagttggtgcaggcctccccatgccggagttcagatggaatcctctacatgggt
aaaaagcaggacatctggtacgtcattgatctcctgactggggagaagcagcagactttg
tcgtcagcctttgcagacagtctctgcccatcaacctcactgctgtatcttgggcgaaca
gagtacaccatcaccatgtatgacaccaaaaccagagagctccggtggaacgccacctat
tttgactatgcagcctcactgcctgaagatgacatggactacaagatgtcccactttgtg
tccaatggcgatggactggtggtgactgtcgacagcgaatctggagatgtcttatggatc
caaaactatggctccccagtagtggccttttacgtgtggcagcgggagggtctgaggaaa
gtgatgcacatcaacgtggccgtggagaccctgcgctacctgaccttcatgtctggggag
gtggggcgcatcacaaagtggaaatacccattccccaaggagacggaggccaagagcaag
ctgacgcctactctgtatgttgggaagtactctaccagcctctatgcctccccatcaatg
gtgcacgaaggggttgctgttgtgccccgaggcagcactctccctctgctggaagggcca
aagactgatggtgtgaccattggggacaaaggggagtgtgtgatcacgcccagcacagac
ctcaagtttgaccctggactcaaagggaaaaacaaactcaactacttgaggaattactgg
cttctgatagggcaccatgaaaccccactgtctgcctctaccaagatgctggagagattc
cccaacaatctgcccaaacatcgggaaaatgtgatacctgctgagtctgagaaaaagagc
tttgaggaagtcatcaacttggttgaccagacttcaaagaacacacccagcaccgtgtct
caggatgtggaggagaagctggctcgggctcctgccaaggccgaggcccctgtggactcc
atgctcaaggacatggccaccatcatcctgagcaccttcctgctgatcggctgggtggcc
ttcatcatcacctacccgctgagtatgcatcagcagcggcggctccagcaccagcagttc
cagaaggagctggagaagatccagctcctgcaacagcagcagctgcccttccagccgcct
ggagatgcgactcaggacactgagctgctggacacttccagccgatactcggagagctcg
ggcaccagcagccccaacacgtcccccagagcttccaaccattctctccactctggcagc
tctgcctccagggccggggccagcccctcgctggagccagacgatgacgatgaggaaacc
agcatggtgattgtcgggaagatttcattctgtcccaaggacgtcctgggccatggagct
gagggcacaattgtgtaccggggcatgtttgacaaccgcgatgtggccgtgaagaggatt
ctacctgagtgtttcagctttgccgaccgcgaggtacagctgctgcgggagtccgacgaa
catccgaacgtgatccgttacttctgtacggagagggaccggcagttccaatacattgcc
atcgagctgtgcgcagccaccctgcaggagtacgtggagcagaaggacttcttccacctt
ggcctggagcccatcaccttgctccagcagaccacctcgggcctggcacacctccactcc
ctcaacattgttcacagagacctgaagccacacaacattctcctctccatgcccaatgca
catggcaggattaaggccatgatctctgactttggcctctgcaagaagctggccgtgggc
aggcacagcttcagccgccgttctggggtgcctggcacagaaggctggattgccccggag
atgctgagtgaagactgcaaggagaaccccacctacacggtggacatcttctctgcgggc
tgcgtcttttactacgtcatctctgaaggcagccacccttttggcaagtccctgcagcgg
caagccaacatcctcctgggcgcctataacctcgactgcttccacccagagaagcacgaa
gatgtcattgcgcgggaactgatagagaagatgattgcgatggaccctcagaaacggccc
tctgcaaagcacgtgctgaaacacccattcttctggagcctggagaagcagctgcagttc
tttcaggatgtgagtgaccgcatagaaaaggaatccttggacggcccgatagtgcggcag
ttagagaaaggcgggcgagctgtggtgaagatggactggcgggagaacatcactgtccct
ctgcagacagatctacgtaaattcagaacctataaaggtggctccattagagacctcctc
cgagccatgagaaataagaagcaccactaccgggagctccctgtggaggtgcgagagacg
ctgggctccctccctgatgactttgtgcgctacttcacatctcgcttcccccacctcctc
tcacacacctaccgggccatggaactgtgcagccaggagagactcttccagccttactat
tgccacgagcccctggagccccagcctccgatgacgcctgacgccctctga
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