Ochotona princeps (American pika): 101527966
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Entry
101527966 CDS
T07609
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 isoform X1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101527966 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
opi01002
]
101527966 (BACE1)
Enzymes [BR:
opi01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
101527966 (BACE1)
Peptidases and inhibitors [BR:
opi01002
]
Aspartic peptidases
Family A1: pepsin family
101527966 (BACE1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
101527966
NCBI-ProteinID:
XP_004585168
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Position
1:complement(37748376..37767811)
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AA seq
501 aa
AA seq
DB search
MAPALPWLLLWMGSGVFPTHGTQHGIRLPLRSGLGGAPLGLRLPRETEEDPEEPSRRGSF
VDMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggccccagccctgccctggctcctgctgtggatgggctccggcgtgttccctacccat
ggcacccagcatggcatccggctgcccctccgcagtggccttgggggggcccccctgggg
ctccgattgcctcgggagaccgaggaggacccagaggagccaagccggaggggcagcttt
gtggacatggtcgacaacctgcggggcaagtcgggtcagggctactatgtggagatgacc
gtgggcagccctccacaaacgctcaacatcctggtggacacaggcagcagcaacttcgca
gtaggagccgccccgcaccccttcctgcatcgctactaccagaggcagctgtccagcaca
taccgggacctccgcaagggtgtatatgtgccctacacccagggcaagtgggaaggggag
ttgggcactgacctggtgagcatccctcacggccccaacgtcactgtgcgtgccaacatc
gctgccattacggaatcggacaagttcttcatcaacggctccaactgggagggcatccta
gggctggcctatgctgagattgccaggcctgatgactccctggagcccttcttcgactcc
ctggtaaagcagacccatgttcccaacctcttctccttgcagctctgtggtgctggcttc
cccctcaaccagtctgaggtgctagcctcagttggagggagtatgatcattgggggaatt
gaccactcgctgtacacgggcagcctctggtacactcccatccggcgggaatggtattat
gaggtaatcattgtgcgggtagagatcaatggacaagatctgaaaatggactgcaaggag
tacaattacgacaagagcattgtggacagtggcaccaccaacctccgactgcccaagaaa
gtgtttgaagctgcagtaaaatcgatcaaggcagcctcctcgacggagaagtttccagat
ggtttctggctaggggaacagctggtgtgctggcaagcaggcaccaccccttggaacatt
ttcccagtcatctccctctacctcatgggtgaggtcaccaatcagtccttccgcatcacg
atccttccacagcaatacctgcggccagtggaagatgtggccacgtcccaggacgactgt
tacaagtttgccatctcacagtcatcaaccgggactgtcatgggagctgtcatcatggag
ggcttctatgttgtttttgatcgagcccgaaaacgaattggctttgccgtcagcgcctgc
catgtgcatgacgagttcaggacagctgcagtggaaggcccttttgtcaccctggacatg
gaagactgtggctacaacattccacagacagacgaatcaaccctcatgaccatagcctac
gtcatggctgccatctgcgctctcttcatgctgcccctctgcctcatggtgtgtcagtgg
cgctgcctccgctgcctgcgccatcagcatgacgactttgctgatgacatctccctacta
aagtga
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